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N-TETRADECYLPHOSPHONIC ACID

CAS No.
4671-75-4
Chemical Name:
N-TETRADECYLPHOSPHONIC ACID
Synonyms
TDPA;TETRADECYL PHOSPHONATE;myristylphosphonic acid;tetradecyl-phosphonicaci;tetradecanephosphonicacid;TETRADECYLPHOSPHONIC ACID;N-TETRADECYLPHOSPHONIC ACID;1-tetradecylphosphonic acid;1-TETRADECANEPHOSPHONIC ACID;P-tetradecyl-Phosphonic acid
CBNumber:
CB2309695
Molecular Formula:
C14H31O3P
Molecular Weight:
278.37
MDL Number:
MFCD00015834
MOL File:
4671-75-4.mol
Last updated:2024-12-18 14:07:02

N-TETRADECYLPHOSPHONIC ACID Properties

Melting point 96-98°C
Boiling point 175.8°C
Density 0.998±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility ≥27.8 mg/mL in ETOH; insoluble in H2O; ≥2.27 mg/mL in DMSO with gentle warming and ultrasonic
pka 2.65±0.10(Predicted)
form Powder
color white to off-white
Water Solubility Soluble in ethanol, dimethyl sulfoxide and dimethyl formamide. Partially soluble in water.
InChIKey BVQJQTMSTANITJ-UHFFFAOYSA-N
CAS DataBase Reference 4671-75-4
EPA Substance Registry System Phosphonic acid, tetradecyl- (4671-75-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H303-H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Risk Statements  36/37/38
Safety Statements  26-36/37/39
WGK Germany  2
RTECS  TA0460000
TSCA  Yes
HS Code  29319090
NFPA 704
0
0 0

N-TETRADECYLPHOSPHONIC ACID price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 736414 Tetradecylphosphonic acid 97% 4671-75-4 1g $113 2024-03-01 Buy
Sigma-Aldrich 736414 Tetradecylphosphonic acid 97% 4671-75-4 5g $331 2024-03-01 Buy
Sigma-Aldrich 736414 Tetradecylphosphonic acid 98% 4671-75-4 100G $1420 2023-06-20 Buy
TCI Chemical T3183 Tetradecylphosphonic Acid >98.0%(T) 4671-75-4 1g $87 2024-03-01 Buy
TCI Chemical T3183 Tetradecylphosphonic Acid >98.0%(T) 4671-75-4 5g $308 2024-03-01 Buy
Product number Packaging Price Buy
736414 1g $113 Buy
736414 5g $331 Buy
736414 100G $1420 Buy
T3183 1g $87 Buy
T3183 5g $308 Buy

N-TETRADECYLPHOSPHONIC ACID Chemical Properties,Uses,Production

Physical state

N-TETRADECYLPHOSPHONIC ACID is a white to off-white powder.    

Shipping Condition

Room Temperature; may vary elsewhere.

Uses

1-Tetradecylphosphonic acid is used to functionalize the surface of BaTiO3 nanoparticles.

Uses

TDPA can be used to cap copper nanoparticles to protect them from oxidation. It may also be used in the synthesis of cadmium sulfate (CdS) core, which can be used in the fabrication of cadmium selenium (CdSe)/CdS core quantum dots (QDs). It may also be coated on caesium lead bromide (CsPbBr3) perovskite quantum dots for the development of white light emitting diodes (wLED).

General Description

Tetradecylphosphonic acid forms a self-assembled monolayer (SAM) to functionalize a variety of nanoparticles.

Biological Activity

tetradecyl phosphonate is a pan-antagonist of lysophosphatidic acid 1 (lpa1), lpa2, and lpa3 receptors. the ic50 value for inhibition of lpa-induced calcium mobilization was 10 μm, 5.5 μm, and 3.1 μm, respectively. at a concentration of 10 μm, tetradecyl phosphonate activates a peroxisome proliferator-activated receptor γ reporter construct 4-fold when compared with the controls and partially inhibits autotaxin with an ic50 value of approximately 3 μm [1].lysophosphatidic acid (lpa), also known as autotaxin (atx), is a lipid signalling molecule formed by the hydrolysis of lysophosphatidyl choline by lysophospholipase d [2]. lpa signals through four different g protein-coupled receptors, named as lpa1/edg-2, lpa2/edg-4, lpa3/edg-7, and lpa4/gpr23 [3]. it has been reported that lpa was involved in activating peroxisome proliferator-activated receptor γ (pparγ) [4].

References

[1]. durgam g g, virag t, walker m d, et al. synthesis, structure activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of pparγ, and inhibitors of autotaxin[j]. journal of medicinal chemistry, 2005, 48(15): 4919-4930.
[2]. tokumura a, majima e, kariya y, et al. identification of human plasma lysophospholipase d, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase[j]. journal of biological chemistry, 2002, 277(42): 39436-39442.
[3]. noguchi k, ishii s, shimizu t. identification of p2y9/gpr23 as a novel g protein-coupled receptor for lysophosphatidic acid, structurally distant from the edg family[j]. journal of biological chemistry, 2003, 278(28): 25600-25606.
[4]. mcintyre t m, pontsler a v, silva a r, et al. identification of an intracellular receptor for lysophosphatidic acid (lpa): lpa is a transcellular pparγ agonist[j]. proceedings of the national academy of sciences, 2003, 100(1): 131-136.

N-TETRADECYLPHOSPHONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 101)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
18192627656 1012@dideu.com China 3003 58
Hangzhou FandaChem Co.,Ltd.
+8615858145714 FandaChem@Gmail.com China 9087 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Zhengzhou Yuanli Biological Technology Co., Ltd
0086-371-67897895 info@zzyuanli.cn CHINA 136 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
CD Chemical Group Limited
+8615986615575 info@codchem.com China 20342 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
ZHEJIANG JIUZHOU CHEM CO., LTD
+86-0576225566889 +86-13454675544 admin@jiuzhou-chem.com;jamie@jiuzhou-chem.com;alice@jiuzhou-chem.com China 12272 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49978 58

View Lastest Price from N-TETRADECYLPHOSPHONIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Tetradecylphosphonic Acid pictures 2024-08-05 1-Tetradecylphosphonic Acid
4671-75-4
US $1.00-22.00 / KG 1KG 99% 100000KG Shaanxi Dideu Medichem Co. Ltd
 TDPA pictures 2019-07-06 TDPA
4671-75-4
US $1.00 / KG 1KG 98% 1ton Career Henan Chemical Co
  •  TDPA pictures
  • TDPA
    4671-75-4
  • US $1.00 / KG
  • 98%
  • Career Henan Chemical Co

N-TETRADECYLPHOSPHONIC ACID Spectrum

TDPA TETRADECYL PHOSPHONATE TETRADECYLPHOSPHONIC ACID N-TETRADECYLPHOSPHONIC ACID 1-TETRADECANEPHOSPHONIC ACID tetradecanephosphonicacid tetradecyl-phosphonicaci n-Tetradecylphosphonicacid,min.97% 1-tetradecylphosphonic acid Tetradecylphosphonic acid, 98 % n-Tetradecylphosphonic acid, min. 97% n-Tetradecylphosphonicacid,98% myristylphosphonic acid P-tetradecyl-Phosphonic acid Phosphonic acid, P-tetradecyl- n-Tetradecylphosphonic acid, min. 97% TDPA 4671-75-4 111-11-7 CH3CH213POOH2 organic phosphonic acid