Propargyl-PEG6-acid
- CAS No.
- 1951438-84-8
- Chemical Name:
- Propargyl-PEG6-acid
- Synonyms
- CAS_1951438-84-8;Propargyl-PEG6-acid;Propargyl-PEG5-C2-COOH;Propyne-PEG5-CH2CH2COOH;Propargyl-PEG5-CH2CH2COOH;Propargyl-PEG6-Propionic Acid;4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid;Propargyl-PEG5-CH2CH2COOH/4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid
- CBNumber:
- CB23134212
- Molecular Formula:
- C16H28O8
- Molecular Weight:
- 348.39
- MDL Number:
- MFCD28950778
- MOL File:
- 1951438-84-8.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319 |
| Precautionary statements | P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312 |
Propargyl-PEG6-acid price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 902667 | Propargyl-PEG6-acid | 1951438-84-8 | 250mg | $482 | 2024-03-01 | Buy |
| Sigma-Aldrich | 902667 | Propargyl-PEG6-acid | 1951438-84-8 | 1g | $1240 | 2023-06-20 | Buy |
| Activate Scientific | AS104184 | Propargyl-PEG5-CH2CH2COOH 95+% | 1951438-84-8 | 5G | $1478 | 2021-12-16 | Buy |
| Apolloscientific | BIPG1707 | Propargyl-PEG6-acid | 1951438-84-8 | 100mg | $507 | 2021-12-16 | Buy |
| Activate Scientific | AS104184 | Propargyl-PEG5-CH2CH2COOH 95+% | 1951438-84-8 | 1g | $583 | 2021-12-16 | Buy |
Propargyl-PEG6-acid Chemical Properties,Uses,Production
Description
Propargyl-PEG6-acid comprises propargyl and carboxylic acid functional groups. The acid group reacts with primary amines in the presence of activators (e.g. EDC, or HATU).The propargyl group reacts with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The molecule has good solubility in aqueous environment.
Uses
This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG6-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
reaction suitability
reaction type: click chemistry
reagent type: cross-linking reagent
Propargyl-PEG6-acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| airuikechemical co., ltd. | +86-18353166132 +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3148 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
View Lastest Price from Propargyl-PEG6-acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-24 | Propargyl-peg6-acid
1951438-84-8
|
US $0.00-0.00 / Kg | 1Kg | 99.9% | 200tons | airuikechemical co., ltd. | |
 |
2024-10-24 | Propargyl-PEG6-acid
1951438-84-8
|
US $0.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2024-03-26 | Propargyl-PEG6-acid
1951438-84-8
|
US $0.00 / g | 1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-
- Propargyl-peg6-acid
1951438-84-8
- US $0.00-0.00 / Kg
- 99.9%
- airuikechemical co., ltd.
-
- Propargyl-PEG6-acid
1951438-84-8
- US $0.00 / mg
- TargetMol Chemicals Inc.
-
- Propargyl-PEG6-acid
1951438-84-8
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
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