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PtdIns-(3,4,5)-P3-biotinamide (sodium salt)

CAS No.
1415684-80-8
Chemical Name:
PtdIns-(3,4,5)-P3-biotinamide (sodium salt)
Synonyms
IIJJVXPPNNJTJF-YNHNOJPWSA-J;PtdIns-(3,4,5)-P3-biotinamide (sodium salt)
CBNumber:
CB23136771
Molecular Formula:
C35H66N3NaO24P4S
Molecular Weight:
1091.85
MDL Number:
MFCD28899351
MOL File:
1415684-80-8.mol
Last updated:2023-05-21 10:59:17

PtdIns-(3,4,5)-P3-biotinamide (sodium salt) Properties

storage temp. Store at -20°C
solubility H2O: 1 mg/ml
form A lyophilized powder

PtdIns-(3,4,5)-P3-biotinamide (sodium salt) price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10009531 PtdIns-(3,4,5)-P3-biotin (sodium salt) ≥98% 1415684-80-8 10μg $158 2024-03-01 Buy
Cayman Chemical 10009531 PtdIns-(3,4,5)-P3-biotin (sodium salt) ≥98% 1415684-80-8 25μg $374 2024-03-01 Buy
Cayman Chemical 10009531 PtdIns-(3,4,5)-P3-biotin (sodium salt) ≥98% 1415684-80-8 50μg $643 2024-03-01 Buy
Cayman Chemical 10009531 PtdIns-(3,4,5)-P3-biotin (sodium salt) ≥98% 1415684-80-8 100μg $1018 2024-03-01 Buy
Product number Packaging Price Buy
10009531 10μg $158 Buy
10009531 25μg $374 Buy
10009531 50μg $643 Buy
10009531 100μg $1018 Buy

PtdIns-(3,4,5)-P3-biotinamide (sodium salt) Chemical Properties,Uses,Production

Description

The PtdIn phosphates play an important role in the generation and transduction of intracellular signals.1,2,3 PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.

References

1. Majerus, P.W. Inositol phosphate biochemistry Annu. Rev. Biochem. 61,225-250(1992).
2. Exton, J.H. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins Annu. Rev. Pharmacol. Toxicol. 36,481-509(1996).
3. Rückle, T., Schwarz, M.K., and Rommel, C. PI3Kγ inhibition: Towards an 'aspirin of the 21st century'? Nat. Rev. Drug Discov. 5(11),903-918(2006).

PtdIns-(3,4,5)-P3-biotinamide (sodium salt) Preparation Products And Raw materials

Raw materials

Preparation Products

PtdIns-(3,4,5)-P3-biotinamide (sodium salt) Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9707 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Shanghai Universal Biotech Co.,Ltd 18768175414 gaojun@univ-bio.com China 24998 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28091 58
PtdIns-(3,4,5)-P3-biotinamide (sodium salt) IIJJVXPPNNJTJF-YNHNOJPWSA-J 1415684-80-8