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MRZ 2-514

MRZ 2-514 structure

CAS No.: 202808-11-5

Chemical Name:: MRZ 2-514

Synonyms: 8-bromo-4;MRZ 2-514;5-b]quinolin-1-one;5-dihydroxypyridazino[4;MRZ 2-514, 10 mM in DMSO;8-bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one;Pyridazino[4,5-b]quinoline-1,4-dione, 8-bromo-2,3-dihydro-, 5-oxide;8-Bromo-1,4-dioxo-1,2,3,4-tetrahydropyridazino[4,5-b]quinoline 5-oxide;inhibit,Inhibitor,MRZ 2514,MRZ 2 514,MRZ 2-514,iGluR,Ionotropic glutamate receptors

CBNumber:: CB23175554

Molecular Formula:: C11H6BrN3O3

Molecular Weight:: 308.09

MDL Number:: MFCD31382150

MOL File:: 202808-11-5.mol

Last updated:2024-07-02 08:55:03

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MRZ 2-514 Properties

Density	2.07±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
form	Solid
pka	9.37±0.20(Predicted)
color	Yellow to orange

MRZ 2-514 Chemical Properties,Uses,Production

Biological Activity

MRZ 2-514 is an NMDA receptor (glycineB) antagonist with a Ki of 33 μM.

in vitro

MRZ 2-514 has IC ₅₀ values against peak AMPA-induced currents of 72.7 μM.

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in vivo

MRZ 2/514 has anticonvulsive action in the MES model in mice, and the effect is prolonged by probenecid.

target

Ki: 33 μM (glycineB)

MRZ 2-514 Preparation Products And Raw materials

Raw materials

Preparation Products

MRZ 2-514 Suppliers

Global( 20)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	5944	55
Fan De(Beijing) Biotechnology Co., Ltd.	15911056312	liming@bio-fount.com	China	9729	58
Chunchuang (Wuhan) Technology Co., Ltd	15342225168	yutianchun2007@126.com	China	10003	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 15801484223;	psaitong@jm-bio.com	China	29774	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	62075	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24644	58
Nanjing Tengyi Biotechnology Co., Ltd	025-58851786 17714337195	sales@tybiochem.com	China	6828	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11974	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Tianjin Kailiqi Biotechnology Co., Ltd.	55
Fan De(Beijing) Biotechnology Co., Ltd.	58
Chunchuang (Wuhan) Technology Co., Ltd	58
Beijing Jin Ming Biotechnology Co., Ltd.	58
Bide Pharmatech Ltd.	58
TargetMol Chemicals Inc.	58
Nanjing Tengyi Biotechnology Co., Ltd	58
Shanghai Yifei Biotechnology Co. , Ltd.	58

MRZ 2-514 8-bromo-4 5-dihydroxypyridazino[4 5-b]quinolin-1-one Pyridazino[4,5-b]quinoline-1,4-dione, 8-bromo-2,3-dihydro-, 5-oxide 8-bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one inhibit,Inhibitor,MRZ 2514,MRZ 2 514,MRZ 2-514,iGluR,Ionotropic glutamate receptors 8-Bromo-1,4-dioxo-1,2,3,4-tetrahydropyridazino[4,5-b]quinoline 5-oxide MRZ 2-514, 10 mM in DMSO 202808-11-5