ChemicalBook >> CAS DataBase List >>WAY-151932
WAY-151932
- CAS No.
- 220460-92-4
- Chemical Name:
- WAY-151932
- Synonyms
- VNA-932;WAY-151932;WAY-VNA 932;WAY151932,WAY 151932;Methanone, [2-chloro-4-(3-methyl-1H-pyrazol-1-yl)phenyl]-5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-yl-
- CBNumber:
- CB23175600
- Molecular Formula:
- C23H19ClN4O
- Molecular Weight:
- 402.88
- MDL Number:
- MFCD05662330
- MOL File:
- 220460-92-4.mol
Last updated:2024-07-02 08:55:03
Boiling point | 630.6±55.0 °C(Predicted) |
---|---|
Density | 1.33±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | Soluble in DMSO |
form | Solid |
pka | 0.04±0.12(Predicted) |
color | White to off-white |
FDA UNII | CC7IZ88XD2 |
WAY-151932 Chemical Properties,Uses,Production
Biological Activity
WAY-151932 is an antidiuretic hormone V2 receptor agonist with IC50 of 80.3 and 778 nM in human V2 and V1a binding assays, respectively.
in vitro
WAY-151932 (VNA-932) stimulates cAMP formation in LV2 cells expressing the hV 2 receptors in a dose-dependent manner with an EC 50 of 0.74±0.07 nM.
in vivo
Oral administration of WAY-151932 (VNA-932) to water-loaded conscious rats produces a dose-dependent decrease in urine volume (ED 50 =0.14 mg/kg, 2.5% starch in water vehicle) and a corresponding increase in osmolality without altering the urine electrolyte excretion profile.
target
IC50: 80.3 nM (human-V2 binding), 778 nM (human-V1a binding)
WAY-151932 Preparation Products And Raw materials
Raw materials
Preparation Products
WAY-151932 Suppliers
Global( 8)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
Shanghai Amico Chemicals Co. LTD | 18019252918 | sale@amkchem.com | China | 15015 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd | 021-59167510 18117107507 | vip@med-life.cn | China | 5014 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 28118 | 58 |
220460-92-4(WAY-151932)Related Search:
WAY-151932
VNA-932
Methanone, [2-chloro-4-(3-methyl-1H-pyrazol-1-yl)phenyl]-5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-yl-
WAY-VNA 932
WAY151932,WAY 151932
220460-92-4