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MANOOL

CAS No.
596-85-0
Chemical Name:
MANOOL
Synonyms
MANOOL;Nsc165961;Manool (80%);(13R)-Labda-8(17),14-diene-13-ol;Labda-8(20),14-dien-13-ol, (13R)-;[13R,(+)]-Labda-8(17),14-dien-13-ol;[13R,(+)]-Labda-8(17),14-diene-13-ol;4ARTRANS-5-(-TETRAME-2-METHYLENEDECAHYDR;5-(5,5,8a-Trimethyl-2-methylenedecahydro-1-naphthalenyl)-3-methyl-1-penten-3-ol;(αR,1S,4aS,8aS)-α-Ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-napthalenepropanol
CBNumber:
CB2334659
Molecular Formula:
C20H34O
Molecular Weight:
290.48
MDL Number:
MFCD01310996
MOL File:
596-85-0.mol
Last updated:2024-06-26 18:06:10

MANOOL Properties

Melting point 49-52 °C(lit.)
Boiling point 150-153 °C(Press: 0.3 Torr)
Density 0.93±0.1 g/cm3(Predicted)
Flash point >230 °F
storage temp. 4°C, stored under nitroge
solubility Benzene (Slightly), Chloroform (Slightly), Methanol (Slightly)
pka 14.47±0.29(Predicted)
form Low-Melting Solid
color White to Off-White
Specific Gravity 0.97
Odor Very delicate, woody, dry-sweet, and extremely tenacious odor
LogP 6.790 (est)
FDA UNII AT5PJ0PV00

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09
Signal word  Warning
Hazard statements  H315-H400-H319-H335
Precautionary statements  P273-P391-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

MANOOL price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC E678100 Manool(80%) 596-85-0 100mg $160 2021-12-16 Buy
Biosynth Carbosynth FM65852 Manool 596-85-0 100mg $200 2021-12-16 Buy
AK Scientific 9756AJ Manool 596-85-0 50mg $218 2021-12-16 Buy
American Custom Chemicals Corporation API0003252 MANOOL 95.00% 596-85-0 100MG $329.7 2021-12-16 Buy
Biosynth Carbosynth FM65852 Manool 596-85-0 250mg $350 2021-12-16 Buy
Product number Packaging Price Buy
E678100 100mg $160 Buy
FM65852 100mg $200 Buy
9756AJ 50mg $218 Buy
API0003252 100MG $329.7 Buy
FM65852 250mg $350 Buy

MANOOL Chemical Properties,Uses,Production

Uses

Maintains anti-proliferative activity against human malignant cell strains.

Preparation

By extraction of cornrninuted wood of Dacrydium biforme, a tree indigenous to New Zealand, with alcohol or Acetone. The extract is neutralized with alkali, and the crude Manool may be recrystallized.

Definition

ChEBI: A labdane diterpenoid in which the labdane skeleton has double bonds at positions 8(17) and 14 and carries an R-hydroxy group at position 13.

Cytotoxicity

IC50 (μg/mL): 49.3 (V79), 15.6 (B16F10),17.1 (MCF-7), 6.7 (HeLa), 28.5 (HepG2),9.6 (MO59 J), 6.7 (U343), 13.1 (U251)(de Oliveira et al. 2016)

MANOOL Preparation Products And Raw materials

Raw materials

Preparation Products

MANOOL Suppliers

Global( 36)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22963 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49979 58
Shaanxi Didu New Materials Co. Ltd +86-89586680 +86-13289823923 1026@dideu.com China 8670 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
HBCChem, Inc. +1-510-219-6317 sales@hbcchem.com United States 10648 60
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684; sales@rrkchem.com China 57412 58
BOC Sciences -- info@bocsci.com USA 0 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11217 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44918 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29774 58
MANOOL 4AR-TRANS-5-(1,5,5,8AS-TETRAMETHYL-2-METHYLENEDECAHYDRO-1-NAPHTHALENYL)-3-R-METHYL-1-PENTEN-3-OL 1-Naphthalenepropanol, alpha-ethenyldecahydro-alpha,5,5,8a-tetramethyl-2-methylene-, [1S-[1alpha(S*),4abeta,8aalpha]]- 5-(5,5,8a-Trimethyl-2-methylenedecahydro-1-naphthalenyl)-3-methyl-1-penten-3-ol Labda-8(20),14-dien-13-ol, (13R)- 4ARTRANS-5-(-TETRAME-2-METHYLENEDECAHYDR 1-Naphthalenepropanol, .alpha.-ethenyldecahydro-.alpha.,5,5,8a-tetramethyl-2-methylene-, (.alpha.R,1S,4aS,8aS)- 1-Naphthalenepropanol, .alpha.-ethenyldecahydro-.alpha.,5,5,8A-tetramethyl-2-methylene-, [1S-[1.alpha.(S*),4A.beta.,8A.alpha.]]- Nsc165961 (αR,1S,4aS,8aS)-α-Ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-napthalenepropanol (13R)-Labda-8(17),14-diene-13-ol (1S,4aα,αR)-Decahydro-α-vinyl-α,5,5,8aβ-tetramethyl-2-methylene-1-naphthalene-1-propanol [13R,(+)]-Labda-8(17),14-dien-13-ol [13R,(+)]-Labda-8(17),14-diene-13-ol 1-Naphthalenepropanol, α-ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-, (αR,1S,4aS,8aS)- Manool (80%) (αR,1S,4aS,8aS)-α-Ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-napthalenepropanol 596-85-0 Organic Building Blocks Asymmetric Synthesis Chiral Building Blocks Alcohols Miscellaneous Natural Products