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BMS813160

CAS No.
1286279-29-5
Chemical Name:
BMS813160
Synonyms
CS-2742;BMS813160;BMS-813160;BMS813160;BMS 813160;N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide;Inhibitor,CC chemokine receptor,CCR,dual antagonist,peritonitis,CD11b,BMS-813160,inflammation,CTX,thioglycollate,BMS813160,inhibit,mouse,oral;Acetamide, N-[(1R,2S,5R)-5-[(1,1-dimethylethyl)amino]-2-[(3S)-3-[[7-(1,1-dimethylethyl)pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]-2-oxo-1-pyrrolidinyl]cyclohexyl]-
CBNumber:
CB23364411
Molecular Formula:
C25H40N8O2
Molecular Weight:
484.64
MDL Number:
MFCD31540731
MOL File:
1286279-29-5.mol
Last updated:2024-11-19 23:02:33

BMS813160 Properties

Density 1.31±0.1 g/cm3(Predicted)
storage temp. 4°C, protect from light
solubility DMSO:61.0(Max Conc. mg/mL);125.86(Max Conc. mM)
Ethanol:97.0(Max Conc. mg/mL);200.14(Max Conc. mM)
form A crystalline solid
pka 15.46±0.60(Predicted)
color White to off-white
FDA UNII 83U7957287

BMS813160 price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 28421 BMS 813160 1286279-29-5 1mg $242 2024-03-01 Buy
Cayman Chemical 28421 BMS 813160 1286279-29-5 5mg $965 2024-03-01 Buy
TRC B595925 BMS-813160 1286279-29-5 1mg $305 2021-12-16 Buy
ChemScene CS-0033469 BMS-813160 99.89% 1286279-29-5 10mg $450 2021-12-16 Buy
ChemScene CS-0033469 BMS-813160 99.89% 1286279-29-5 5mg $280 2021-12-16 Buy
Product number Packaging Price Buy
28421 1mg $242 Buy
28421 5mg $965 Buy
B595925 1mg $305 Buy
CS-0033469 10mg $450 Buy
CS-0033469 5mg $280 Buy

BMS813160 Chemical Properties,Uses,Production

Description

BMS 813160 is a dual antagonist of chemokine receptor 2 (CCR2) and CCR5 (IC50s = 6.2 and 3.6 nM, respectively, in radioligand binding assays). It inhibits chemotaxis induced by the CCR2 ligand MCP-1 in THP-1 cells the CCR5 ligand MIP-1β in isolated peripheral T cells with IC50 values of 0.8 and 1.1 nM, respectively. BMS 813160 inhibits peritoneal monocyte and macrophage infiltration in an hCCR-2 KI mouse model of thioglycolate-induced peritonitis, with 54% inhibition when administered at a dose of 50 mg/kg twice per day.

Uses

BMS-813160, a dual CCR2/CCR5 chemokine antagonist.

BMS813160 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 51)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Shenzhen Shengda Pharma Limited
755-85269922 +8613424394241 sales@shengdapharm.com CHINA 310 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38632 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8467 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Wuhan Jingkang en Biomedical Technology Co., Ltd
+8613720134139 orders@jknbiochem.com China 5221 58
Wuhan Jingkangen Biomedical Technology Co., Ltd 13720134139 13720134139 orders@jknbiochem.com China 5797 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3466 58

View Lastest Price from BMS813160 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BMS-813160 pictures 2024-11-19 BMS-813160
1286279-29-5
US $57.00-197.00 / mg 99.78% 10g TargetMol Chemicals Inc.
  • BMS-813160 pictures
  • BMS-813160
    1286279-29-5
  • US $57.00-197.00 / mg
  • 99.78%
  • TargetMol Chemicals Inc.
CS-2742 BMS-813160;BMS813160;BMS 813160 N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide BMS813160 Acetamide, N-[(1R,2S,5R)-5-[(1,1-dimethylethyl)amino]-2-[(3S)-3-[[7-(1,1-dimethylethyl)pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]-2-oxo-1-pyrrolidinyl]cyclohexyl]- Inhibitor,CC chemokine receptor,CCR,dual antagonist,peritonitis,CD11b,BMS-813160,inflammation,CTX,thioglycollate,BMS813160,inhibit,mouse,oral 1286279-29-5