ChemicalBook >> CAS DataBase List >>BMS813160
BMS813160
- CAS No.
- 1286279-29-5
- Chemical Name:
- BMS813160
- Synonyms
- CS-2742;BMS813160;BMS-813160;BMS813160;BMS 813160;N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide;Inhibitor,CC chemokine receptor,CCR,dual antagonist,peritonitis,CD11b,BMS-813160,inflammation,CTX,thioglycollate,BMS813160,inhibit,mouse,oral;Acetamide, N-[(1R,2S,5R)-5-[(1,1-dimethylethyl)amino]-2-[(3S)-3-[[7-(1,1-dimethylethyl)pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]-2-oxo-1-pyrrolidinyl]cyclohexyl]-
- CBNumber:
- CB23364411
- Molecular Formula:
- C25H40N8O2
- Molecular Weight:
- 484.64
- MDL Number:
- MFCD31540731
- MOL File:
- 1286279-29-5.mol
Last updated:2024-11-19 23:02:33
Density | 1.31±0.1 g/cm3(Predicted) |
---|---|
storage temp. | 4°C, protect from light |
solubility |
DMSO:61.0(Max Conc. mg/mL);125.86(Max Conc. mM) Ethanol:97.0(Max Conc. mg/mL);200.14(Max Conc. mM) |
form | A crystalline solid |
pka | 15.46±0.60(Predicted) |
color | White to off-white |
FDA UNII | 83U7957287 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05,GHS08,GHS07 |
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Signal word | Danger | |||||||||
Hazard statements | H315-H318-H334-H317-H341-H361-H370-H335-H413 | |||||||||
Precautionary statements | P201-P202-P260-P264-P270-P272-P273-P280-P284-P302+P352-P304+P341-P305+P351+P338-P310-P308+P313-P321-P362+P364-P333+P313-P342+P311-P363-P405-P501 | |||||||||
NFPA 704 |
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BMS813160 price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 28421 | BMS 813160 | 1286279-29-5 | 1mg | $242 | 2024-03-01 | Buy |
Cayman Chemical | 28421 | BMS 813160 | 1286279-29-5 | 5mg | $965 | 2024-03-01 | Buy |
TRC | B595925 | BMS-813160 | 1286279-29-5 | 1mg | $305 | 2021-12-16 | Buy |
ChemScene | CS-0033469 | BMS-813160 99.89% | 1286279-29-5 | 10mg | $450 | 2021-12-16 | Buy |
ChemScene | CS-0033469 | BMS-813160 99.89% | 1286279-29-5 | 5mg | $280 | 2021-12-16 | Buy |
BMS813160 Chemical Properties,Uses,Production
Description
BMS 813160 is a dual antagonist of chemokine receptor 2 (CCR2) and CCR5 (IC50s = 6.2 and 3.6 nM, respectively, in radioligand binding assays). It inhibits chemotaxis induced by the CCR2 ligand MCP-1 in THP-1 cells the CCR5 ligand MIP-1β in isolated peripheral T cells with IC50 values of 0.8 and 1.1 nM, respectively. BMS 813160 inhibits peritoneal monocyte and macrophage infiltration in an hCCR-2 KI mouse model of thioglycolate-induced peritonitis, with 54% inhibition when administered at a dose of 50 mg/kg twice per day.
Uses
BMS-813160, a dual CCR2/CCR5 chemokine antagonist.
BMS813160 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 51)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
Shenzhen Shengda Pharma Limited | 755-85269922 +8613424394241 | sales@shengdapharm.com | CHINA | 310 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38632 | 58 | |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 5221 | 58 |
Wuhan Jingkangen Biomedical Technology Co., Ltd | 13720134139 13720134139 | orders@jknbiochem.com | China | 5797 | 58 |
ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3466 | 58 |
View Lastest Price from BMS813160 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-19 | BMS-813160
1286279-29-5
|
US $57.00-197.00 / mg | 99.78% | 10g | TargetMol Chemicals Inc. |
- BMS-813160
1286279-29-5
- US $57.00-197.00 / mg
- 99.78%
- TargetMol Chemicals Inc.
1286279-29-5(BMS813160)Related Search:
CS-2742
BMS-813160;BMS813160;BMS 813160
N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide
BMS813160
Acetamide, N-[(1R,2S,5R)-5-[(1,1-dimethylethyl)amino]-2-[(3S)-3-[[7-(1,1-dimethylethyl)pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]-2-oxo-1-pyrrolidinyl]cyclohexyl]-
Inhibitor,CC chemokine receptor,CCR,dual antagonist,peritonitis,CD11b,BMS-813160,inflammation,CTX,thioglycollate,BMS813160,inhibit,mouse,oral
1286279-29-5