Olmesartan
- CAS No.
- 144689-24-7
- Chemical Name:
- Olmesartan
- Synonyms
- Olmesartan Acid;CS 088;CS-415;RNH 6270;CS 088-d6;OMSTint-H;Olmesartan;Olmesartan EP Imp A;Olmesartan (RNH-6270;Olmesartan Olmesartan
- CBNumber:
- CB2350011
- Molecular Formula:
- C24H26N6O3
- Molecular Weight:
- 446.5
- MDL Number:
- MFCD00914967
- MOL File:
- 144689-24-7.mol
- MSDS File:
- SDS
Melting point | 186-188°C |
---|---|
Boiling point | 738.3±70.0 °C(Predicted) |
Density | 1.33 |
storage temp. | 2-8°C |
solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
pka | 2.39±0.50(Predicted) |
form | powder |
color | white to beige |
Stability | Hygroscopic |
CAS DataBase Reference | 144689-24-7(CAS DataBase Reference) |
FDA UNII | 8W1IQP3U10 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H312-H332 |
Precautionary statements | P280-P302+P352-P312-P322-P363-P501-P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501 |
RTECS | NI4014100 |
HS Code | 29339900 |
Hazardous Substances Data | 144689-24-7(Hazardous Substances Data) |
Olmesartan price More Price(38)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML1394 | Olmesartan ≥98% (HPLC) | 144689-24-7 | 50MG | $142 | 2023-06-20 | Buy |
TCI Chemical | O0507 | Olmesartan >98.0%(HPLC) | 144689-24-7 | 100mg | $134 | 2024-03-01 | Buy |
Cayman Chemical | 23412 | Olmesartan ≥98% | 144689-24-7 | 50mg | $68 | 2024-03-01 | Buy |
Cayman Chemical | 23412 | Olmesartan ≥98% | 144689-24-7 | 100mg | $116 | 2024-03-01 | Buy |
Cayman Chemical | 23412 | Olmesartan ≥98% | 144689-24-7 | 250mg | $268 | 2024-03-01 | Buy |
Olmesartan Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
An labelled angiotensin II receptor antagonist. Used as an anti-hypertensive
Uses
An angiotensin II (AT1) receptor antagonist
Uses
Angiotensin II inhibitor, antihypertensive
Uses
Olmesartan Acid (Olmesartan EP Impurity A) is an angiotensin II receptor antagonist. Used as an anti-hypertensive.
Definition
ChEBI: Olmesartan is a biphenylyltetrazole. It has a role as an antihypertensive agent and an angiotensin receptor antagonist.
General Description
Olmesartan medoxomil, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl-5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate (Benicar, Olmetec) uses the tetrazolering system as its acidic system, which participates inreceptor binding.When administered to a patient, the drugis rapidly and completely bioactivated by ester hydrolysis ofthe medoxomil during absorption from the gastrointestinaltract. Once the prodrug is converted to the active form, virtuallyno further metabolism occurs. In September 2007, theFood and Drug Administration (FDA) approved its use as acombination product with the calcium channel blocker amlodipinefor the management of hypertension. This combinationproduct is sold under the tradename of Azor.
Biochem/physiol Actions
Olmesartan possesses anti-inflammatory and anti-oxidative stress properties. It protects neuronal cells against oligomerized amyloid β (Aβ)-induced cellular senescence.
storage
Store at +4°C
Olmesartan Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
Shanghai Longyu Biotechnology Co., Ltd. | +8619521488211 | info@longyupharma.com | China | 2557 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD | +86-027-81302088 +86-13986076795 | Circlepowder02@163.com | CHINA | 279 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
Shanghai Yunao International Trade Co., Ltd | +8617621705551 | asdf@shanghaihg.cn | China | 264 | 58 |
View Lastest Price from Olmesartan manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-04-17 | Olmesartan
144689-24-7
|
US $0.00 / Kg | 1KG | 99% | 100ton | Shanghai Yunao International Trade Co., Ltd | ||
2021-12-23 | Olmesartan
144689-24-7
|
US $0.00 / KG | 1g | 99% | 200kg | WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD | ||
2021-07-09 | Olmesartan
144689-24-7
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
- Olmesartan
144689-24-7
- US $0.00 / Kg
- 99%
- Shanghai Yunao International Trade Co., Ltd
- Olmesartan
144689-24-7
- US $0.00 / KG
- 99%
- WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
- Olmesartan
144689-24-7
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd