SPHINGOSYLPHOSPHORYLCHOLINE
- CAS No.
- 1670-26-4
- Chemical Name:
- SPHINGOSYLPHOSPHORYLCHOLINE
- Synonyms
- SPC;MGC119002;D-ERYTHRO-SPC;Lyso SM (d18:1);LYSO-SPHINGOMYELIN;urocortin 3 (stresscopin);Lyso-Sphingomyelin (d18:1);SPHINGOSYLPHOSPHORYLCHOLINE;spingosyl-phosphorylcholine;Sphingenyl-1-phosphorylcholine
- CBNumber:
- CB2356664
- Molecular Formula:
- C23H49N2O5P
- Molecular Weight:
- 464.62
- MDL Number:
- MFCD02259287
- MOL File:
- 1670-26-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
WGK Germany | 3 |
---|---|
F | 1-8-10 |
SPHINGOSYLPHOSPHORYLCHOLINE price More Price(14)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 10007947 | Lyso-Sphingomyelin (d18:1) ≥98% | 1670-26-4 | 1mg | $90 | 2024-03-01 | Buy |
Cayman Chemical | 10007947 | Lyso-Sphingomyelin (d18:1) ≥98% | 1670-26-4 | 5mg | $401 | 2024-03-01 | Buy |
Sigma-Aldrich | S4257 | Sphingosylphosphoryl-choline ≥98%, powder | 1670-26-4 | 10mg | $332 | 2024-03-01 | Buy |
Sigma-Aldrich | S4257 | Sphingosylphosphoryl-choline ≥98%, powder | 1670-26-4 | 25mg | $473.4 | 2024-03-01 | Buy |
Sigma-Aldrich | 567735 | Sphingosylphosphoryl-choline | 1670-26-4 | 10mg | $535 | 2024-03-01 | Buy |
SPHINGOSYLPHOSPHORYLCHOLINE Chemical Properties,Uses,Production
Chemical Properties
Yellowish Waxy Solid
Uses
Lyso SM (d18:1) has been used:
- to study its effect on the skeletal muscle ryanodine receptor (RyR1), in the presence and absence of calmodulin through single channel recordings in planar lipid bilayers
- as an inhibitor of Ca2+ sensor calmodulin (CaM)
- as a standard in circular dichroism (CD) spectroscopy to determine lipid selectivity of the lipid-peptide interactions
Uses
Neurotrophic effects of Sphingosylphosphorylcholine were studied in cerebellar granule neurons of mice and PC-12 cells.
Uses
Involved in cell regulation, and transmembrane signaling. A putative lipid second messenger, connected via Protein Kinase C to the phosphatidylinositol-derived second messengers for signal transduction.
Definition
ChEBI: Sphingosine-1-phosphocholine is a phosphosphingolipid consisting of sphingosine having a phosphocholine moiety attached to its primary hydroxyl group. It is a phosphosphingolipid, a member of phosphocholines and an ammonium betaine. It is functionally related to a sphingosine. It is a conjugate base of a sphingosylphosphocholine acid and a sphingosine-1-phosphocholine(1+).
General Description
Lyso SM (d18:1), also known as sphingosylphosphorylcholine (SPC), is a bioactive lipid molecule. This lysophospholipid is present in normal blood plasma, ascites and various tissues.
Biochem/physiol Actions
Sphingosylphosphorylcholine (SPC) is a bioactive lipid that mediates intracellular and extracellular signaling. It mobilizes Ca2+ from intracellular stores via an IP3-independent pathway. It stimulates the production of CCL2 that may contribute to development of atherosclerosis. SPC is a ligand for endothelial differentiation gene receptor 3 (EDG3).
SPHINGOSYLPHOSPHORYLCHOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
SPHINGOSYLPHOSPHORYLCHOLINE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Chemson Industrial (Shanghai) Co., Ltd. | 86-21-65208861- 8007 | sales1@chemson.com.cn | CHINA | 117 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29811 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15352 | 58 |
Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94657 | 76 |
View Lastest Price from SPHINGOSYLPHOSPHORYLCHOLINE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-10-28 | Lysosphingomyelin (d18:1)
1670-26-4
|
US $199.00 / mg | 10g | TargetMol Chemicals Inc. | ||||
2020-01-13 | SPHINGOSYLPHOSPHORYLCHOLINE
1670-26-4
|
US $1.00 / KG | 1KG | 98%-99.9% | 200kg | Career Henan Chemical Co |
- Lysosphingomyelin (d18:1)
1670-26-4
- US $199.00 / mg
- TargetMol Chemicals Inc.
- SPHINGOSYLPHOSPHORYLCHOLINE
1670-26-4
- US $1.00 / KG
- 98%-99.9%
- Career Henan Chemical Co
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