ChemicalBook >> CAS DataBase List >>3alpha-Hydroxy-7-oxo-5beta-cholanic Acid
3alpha-Hydroxy-7-oxo-5beta-cholanic Acid
- CAS No.
- 4651-67-6
- Chemical Name:
- 3alpha-Hydroxy-7-oxo-5beta-cholanic Acid
- Synonyms
- 7-KETOLITHOCHOLIC ACID;Nutriacholic acid;7-Oxolithocholic acid;3α-Hydroxy-7-oxo-5β-cholan-24-oic acid;3α-Hydroxy-7-ketocholanic acid;Chenodeoxycholic acid EP Impurity F;3ALPHA-HYDROXY-7-KETO-5BETA-CHOLANIC ACID;(R)-4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-Hydroxy-10,13-diMethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid;OCA-A;7-KLA
- CBNumber:
- CB2430908
- Molecular Formula:
- C24H38O4
- Molecular Weight:
- 390.56
- MDL Number:
- MFCD00271393
- MOL File:
- 4651-67-6.mol
- MSDS File:
- SDS
Last updated:2024-11-19 20:33:22
| Melting point | 205°C |
|---|---|
| Boiling point | 545.9±25.0 °C(Predicted) |
| Density | 1.124±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 4.76±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | 2.062mg/L at 25℃ |
| InChIKey | DXOCDBGWDZAYRQ-QHVQYUNXNA-N |
| SMILES | C(O)(=O)CC[C@H]([C@@H]1[C@@]2(C)CC[C@]3([H])[C@@]4(C)CC[C@@H](O)C[C@@]4([H])CC(=O)[C@@]3([H])[C@]2([H])CC1)C |&1:5,6,7,11,13,17,20,25,27,r| |
| LogP | 3.48 at 20℃ |
| FDA UNII | Y1357H1A28 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| NFPA 704 |
|
3alpha-Hydroxy-7-oxo-5beta-cholanic Acid price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29546 | 7-keto Lithocholic Acid | 4651-67-6 | 1g | $84 | 2024-03-01 | Buy |
| Cayman Chemical | 29546 | 7-keto Lithocholic Acid | 4651-67-6 | 10g | $680 | 2024-03-01 | Buy |
| Cayman Chemical | 29546 | 7-keto Lithocholic Acid | 4651-67-6 | 500mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 29546 | 7-keto Lithocholic Acid | 4651-67-6 | 5g | $384 | 2024-03-01 | Buy |
| Medical Isotopes, Inc. | 71777 | NutriacholicAcid | 4651-67-6 | 1g | $650 | 2021-12-16 | Buy |
3alpha-Hydroxy-7-oxo-5beta-cholanic Acid Chemical Properties,Uses,Production
Uses
Nutriacholic Acid (Ursodeoxycholic Acid EP Impurity F) is derivative of Lithocholic Acid (L469180), a cholic acid derivative as TGR5 modulator.
Uses
3alpha-Hydroxy-7-oxo-5beta-cholanic Acid is an intermediate in organic synthesis and pharmaceutical research and development. It can be used to synthesize the choleretic drug Obeticholic acid. Obeticholic acid can inhibit cholic acid synthesis. It is commonly used to treat primary biliary cirrhosis and nonalcoholic fatty liver disease.
Definition
ChEBI: 7-oxolithocholic acid is a bile acid that is lithocholic acid carrying an additional oxo substituent at position 7. It has a role as a human metabolite. It is a bile acid, a monohydroxy-5beta-cholanic acid, an oxo-5beta-cholanic acid and a 3alpha-hydroxy steroid. It is functionally related to a lithocholic acid. It is a conjugate acid of a 7-oxolithocholate.
Flammability and Explosibility
Non flammable
3alpha-Hydroxy-7-oxo-5beta-cholanic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 346)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| XuZhou Magic Biotechnology Co., Ltd. | +undefined13921770081 | SVP01@magicbiotech.cn | China | 92 | 58 |
| Wuhan Han Sheng New Material Technology Co.，Ltd | +8617798174412 | admin01@hsnm.com.cn | China | 2097 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18774 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9206 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
View Lastest Price from 3alpha-Hydroxy-7-oxo-5beta-cholanic Acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | 7-Ketolithocholic acid
4651-67-6
|
US $41.00 / mg | 98.18% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-19 | 7-Ketolithocholic acid
4651-67-6
|
US $41.00 / mg | 98.18% | 10g | TargetMol Chemicals Inc. | ||
 |
2023-09-14 | 3alpha-Hydroxy-7-oxo-5beta-cholanic Acid
4651-67-6
|
US $0.00-0.00 / kg | 1kg | 99% | 50tons | Wuhan Han Sheng New Material Technology Co.，Ltd |
-
- 7-Ketolithocholic acid
4651-67-6
- US $41.00 / mg
- 98.18%
- TargetMol Chemicals Inc.
-
- 7-Ketolithocholic acid
4651-67-6
- US $41.00 / mg
- 98.18%
- TargetMol Chemicals Inc.
-
- 3alpha-Hydroxy-7-oxo-5beta-cholanic Acid
4651-67-6
- US $0.00-0.00 / kg
- 99%
- Wuhan Han Sheng New Material Technology Co.，Ltd
4651-67-6(3alpha-Hydroxy-7-oxo-5beta-cholanic Acid)Related Search:
7-ketolithocholic Methyl ester
Cholan-24-oic acid, 7-hydrazono-3,12-dihydroxy-, (3α,5β,12α)-
(3α,5β,12α)-(3′α,5′β,12′α)-7,7′-(1,2-Hydrazinediylidene)bis[3,12-dihydroxycholan-24-oic acid]
7-KETODEOXYCHOLIC ACID
4-[(5S,7S,8S,10S,13R,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
(+)-NEOMENTHOL
(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
(2S)-2-[[[(1,1-Dimethylethyl)diphenylsilyl]oxy]methyl]-1,3-oxathiolan-5-ol 5-Acetate
Emtricitabine Impurity 18
Emtricitabine Impurity
1of4
3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID
5-BETA-CHOLANIC ACID-3-ALPHA-OL-7-ONE
3alpha-Hydroxy-7-oxo-5?cholanic acid
3-alpha-hydroxy-7-oxo-5-beta-cholan-24-oic acid
Hydroxycholanicacid
4-(3-hydroxy-10,13-dimethyl-7-oxo-1,2,3,4,5,6,8,9,11,12,14,15,16,17-tetrade cahydrocyclopenta[a]phenanthren-17-yl)pentanoic acid
ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID
alpha-Hydroxy-7-oxo-5beta-cholic acid
3-ALPHA-HYDROXY-7-OXO-5-BETA-CHOLANOICACID
3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID 97+%
Cholan-24-oic acid, 3-hydroxy-7-oxo-, (3.alpha.,5.beta.)-
Nsc226118
3-Hydoxy-7-ketocholanic acid
3α-Hydroxy-7-oxo-5β-cholanic acid
7-Ketochenodeoxycholic acid
7-Oxo-3α-hydroxy-5β-cholan-24-oic acid
3-Hydroxy-7-oxocholan-24-oic acid
3a-Hydroxy-7-oxo-5b-cholanic acid
3alpha-Hydroxy-7-oxo-5beta-cholic acid
(3α,5β)-3-Hydroxy-7-oxo-Cholan-24-oic acid
Cholan-24-oic acid,6-ethyl-3,7-dihydroxy-,(3α,5β,6β,7β)-
3-alpha-hydroxy-7-oxo-5-beta-cholan-24-oic
obeticholic acid intermediate 1
3α-Hydroxy-7-keto-5β-cholanic Acid
3Α--hydroxy-7-oxo -5Β- bile acid
OCA-A
3ɑ-Hydroxy-7-Oxo-5β-Cholanic Acid
3ALFA-HYDROXI-7KETO-5BETA-CHOLAN-24-ACID
3α-Hydroxy-7-oxo-5β-cholic acid
7-Ketolithocholic acid (3alpha-hydroxy-7-oxo-5beta-Cholanic acid)
ursodeoxycholic acid oxide
Ursodeoxycholic Acid EP Impurity F(7-Ketolithocholic Acid)
Ursodeoxycholic Acid Impurity 6（Ursodeoxycholic Acid EP Impurity F）
3α-hydroxy-7-oxo-5β-cholanoic acid
3α-Hydroxy-7-oxo-5b-cholanic acid, 98%
Chenodeoxycholic Acid Impurity 6
Ursodeoxycholic Acid EP Impurity F
3α-Hydroxy-7-oxo-5β-cholanicAcid>
5β-CHOLANIC acid-3α-OL-7-ONE
Cholan-24-oic acid, 3-hydroxy-7-oxo-, (3α,5β)-
Emtricitabine Impurity 33
7-oxolithocholicaci
3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID USP/EP/BP
Chenodeoxycholic Acid Impurity 6(Chenodeoxycholic Acid EP Impurity F)
3α-Hydroxy-7-keto-5β-cholanic Acid
Chenodeoxycholic Acid EP Impurity F (Ursodeoxycholic Acid EP Impurity F/ 7-Oxo Ursodeoxycholic Acid/ 7-Oxo Chenodeoxycholic Acid)
Ursodeoxycholic Acid EP Impurity F (Chenodeoxycholic Acid EP Impurity F/ 7-Oxo Ursodeoxycholic Acid/ 7-Oxo Chenodeoxycholic Acid)
Ursodiol Impurity F
3α-Hydroxy-7-oxo-5β-cholanic acid
Ursodeoxycholic Acid EP Impurity F,3α-hydroxy-7-oxo-5β-cholan-24-oic acid
7-KETOLITHOCHOLIC ACID
3ALPHA-HYDROXY-7-KETO-5BETA-CHOLANIC ACID
Nutriacholic acid
3α-Hydroxy-7-oxo-5β-cholan-24-oic acid
7-Oxolithocholic acid
(R)-4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-Hydroxy-10,13-diMethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
3α-Hydroxy-7-ketocholanic acid
Chenodeoxycholic acid EP Impurity F