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GC 14
- CAS No.
- 447415-34-1
- Chemical Name:
- GC 14
- Synonyms
- GC 14;Acetic acid, 2-[4-[[6-hydroxy-5-(1-methylethyl)-4'-nitro[1,1'-biphenyl]-3-yl]methyl]-3,5-dimethylphenoxy]-
- CBNumber:
- CB24672634
- Molecular Formula:
- C26H27NO6
- Molecular Weight:
- 449.5
- MDL Number:
- MFCD31657389
- MOL File:
- 447415-34-1.mol
Last updated:2023-05-21 10:59:17
GC 14 Chemical Properties,Uses,Production
Description
GC 14 is a thyroid hormone antagonist.
GC 14 contains extensions at the 5′-position of the outer thyronine ring or from the bridging carbon and has only a modest affinity and potency for the thyroid hormone receptor (TR) that limits studies of their antagonistic actions[2].
References
[1]. Chiellini G, et al. Synthesis and biological activity of novel thyroid hormone analogues: 5'-aryl substituted GC-1 derivatives. Bioorg Med Chem. 2002 Feb;10(2):333-46. [2]. Nguyen NH, et al. Rational design and synthesis of a novel thyroid hormone antagonist that blocks coactivator recruitment. J Med Chem. 2002 Jul 18;45(15):3310-20.
GC 14 Preparation Products And Raw materials
Raw materials
Preparation Products
GC 14 Suppliers
Global( 5)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shanghai Akasaka Biotechnology Co., Ltd. | 15121162054 | CHINA | 635 | 58 | |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29778 | 58 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | 2261760024@qq.com | China | 4908 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19696 | 58 |
GC 14
Acetic acid, 2-[4-[[6-hydroxy-5-(1-methylethyl)-4'-nitro[1,1'-biphenyl]-3-yl]methyl]-3,5-dimethylphenoxy]-
447415-34-1