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CLK1-IN-1

CLK1-IN-1 structure

CAS No.: 2123491-32-5

Chemical Name:: CLK1-IN-1

Synonyms: CLK1-IN-1;CLK1 inhibitor 1;CLK1IN1,CLK1 IN 1,CLK-1-IN-1;1H-1,2,3-Triazolo[4,5-c]quinoline, 8-(5-benzoxazolyl)-1-[(1S)-1-(4-fluorophenyl)ethyl]-;(S)-5-(1-(1-(4-Fluorophenyl)ethyl)-1H-[1,2,3]triazolo[4,5-c]quinolin-8-yl)benzo[d]oxazole

CBNumber:: CB24797038

Molecular Formula:: C24H16FN5O

Molecular Weight:: 409.42

MDL Number:: MFCD31692336

MOL File:: 2123491-32-5.mol

Last updated:2025-04-17 18:22:24

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CLK1-IN-1 Properties

Boiling point	641.5±55.0 °C(Predicted)
Density	1.43±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : ≥ 50 mg/mL (122.12 mM)
form	Solid
pka	4.85±0.30(Predicted)
color	White to off-white

CLK1-IN-1 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0023822	CLK1-IN-1 99.03%	2123491-32-5	5mg	$450	2021-12-16	Buy
ChemScene	CS-0023822	CLK1-IN-1 99.03%	2123491-32-5	10mg	$750	2021-12-16	Buy
ChemScene	CS-0023822	CLK1-IN-1 99.03%	2123491-32-5	25mg	$1500	2021-12-16	Buy
ChemScene	CS-0023822	CLK1-IN-1 99.03%	2123491-32-5	50mg	$2400	2021-12-16	Buy
ChemScene	CS-0023822	CLK1-IN-1 99.03%	2123491-32-5	100mg	$3800	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0023822	5mg	$450	Buy
CS-0023822	10mg	$750	Buy
CS-0023822	25mg	$1500	Buy
CS-0023822	50mg	$2400	Buy
CS-0023822	100mg	$3800	Buy

CLK1-IN-1 Chemical Properties,Uses,Production

Uses

CLK1-IN-1 is a potent and selective of Cdc2-like kinase 1 (CLK1) inhibitor, with an IC50 of 2 nM.

in vivo

APAP exposure results in severe liver injury, and treatment with CLK1-IN-1 (ip, 30 mg/kg) imparts a significant hepatoprotective effect. The results show that treatment with CLK1-IN-1 decreases serum ALT and AST levels significantly such that both marker enzymes return to normal levels^[1].

IC 50

CLK1: 2 nM (IC₅₀)

References

[1] Sun QZ, et al. Discovery of Potent and Selective Inhibitors of Cdc2-Like Kinase 1 (CLK1) as a New Class of Autophagy Inducers. J Med Chem. 2017 Jul 27;60(14):6337-6352. DOI:10.1021/acs.jmedchem.7b00665

CLK1-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

CLK1-IN-1 Suppliers

Global( 16)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32159	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38630	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42056	58
Aladdin Scientific		tp@aladdinsci.com	United States	52924	58
TargetMol Chemicals Inc.	+8613564774135	zijue.cai@tsbiochem.com	United States	19881	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	12952	65
Fan De(Beijing) Biotechnology Co., Ltd.	15911056312	liming@bio-fount.com	China	9729	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Shanghai hongqu biomedical technology co. LTD	88888888888	hongquchem@qq.com	China	5132	58
cjbscvictory	13348960310 13348960310	3003867561@qq.com	China	10524	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Aladdin Scientific	58
TargetMol Chemicals Inc.	58
BOC Sciences	65
Fan De(Beijing) Biotechnology Co., Ltd.	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Shanghai hongqu biomedical technology co. LTD	58
cjbscvictory	58

View Lastest Price from CLK1-IN-1 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-10-28	CLK1-IN-1 2123491-32-5	US $2500.00-1980.00 / mg			10g	TargetMol Chemicals Inc.

CLK1-IN-1
2123491-32-5
US $2500.00-1980.00 / mg
TargetMol Chemicals Inc.

CLK1-IN-1 CLK1 inhibitor 1 1H-1,2,3-Triazolo[4,5-c]quinoline, 8-(5-benzoxazolyl)-1-[(1S)-1-(4-fluorophenyl)ethyl]- CLK1IN1,CLK1 IN 1,CLK-1-IN-1 (S)-5-(1-(1-(4-Fluorophenyl)ethyl)-1H-[1,2,3]triazolo[4,5-c]quinolin-8-yl)benzo[d]oxazole 2123491-32-5 C24H16FN5O