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MRS1177
- CAS No.
- 183721-13-3
- Chemical Name:
- MRS1177
- Synonyms
- MRS1177;MRS-1177,MRS1177;Benzamide, N-[9-chloro-2-(2-furanyl)[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-
- CBNumber:
- CB24845023
- Molecular Formula:
- C20H12ClN5O2
- Molecular Weight:
- 389.79
- MDL Number:
- MFCD31807617
- MOL File:
- 183721-13-3.mol
Last updated:2023-05-21 10:59:17
MRS1177 Chemical Properties,Uses,Production
Description
MRS1177 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 0.3 nM.
MRS1177 (compound 2b) is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist[1]. The Ki value of MRS1177 (compound 55) with hA3AR is 0.3 nM[2].
References
[1]. Tafi A, et al. Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models. J Med Chem. 2006 Jul 13;49(14):4085-97. [2]. Cheong SL, et al. Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists. Bioorg Med Chem Lett. 2011 May 15;21(10):2898-905.
MRS1177 Preparation Products And Raw materials
Raw materials
Preparation Products
MRS1177 Suppliers
Global( 5)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7887 | 56 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9412 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29778 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24647 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 56 |
| DC Chemicals | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
MRS1177
MRS-1177,MRS1177
Benzamide, N-[9-chloro-2-(2-furanyl)[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-
183721-13-3