Amino-Tri-(carboxyethoxymethyl)-methane
- CAS No.
- 174362-95-9
- Chemical Name:
- Amino-Tri-(carboxyethoxymethyl)-methane
- Synonyms
- Amino-Tri-(carboxyethoxymethyl)-methane;Tri[(2-carboxyethoxy)methyl](amino)methane;Amino-Tri-(carboxyethoxymethyl)-methane (HCl);3,3'-((2-amino-2-((2-carboxyethoxy)methyl)propane-1,3-diyl)bis(oxy))dipropionic acid;3,3’-[[2-Amino-2-[(2-carboxyethoxy)methyl]propane-1,3-diyl]bis(oxy)]dipropanoic Acid;Propanoic acid, 3,3'-[[2-amino-2-[(2-carboxyethoxy)methyl]-1,3-propanediyl]bis(oxy)]bis-
- CBNumber:
- CB24849531
- Molecular Formula:
- C13H23NO9
- Molecular Weight:
- 337.32
- MDL Number:
- MFCD31615450
- MOL File:
- 174362-95-9.mol
Amino-Tri-(carboxyethoxymethyl)-methane price
Amino-Tri-(carboxyethoxymethyl)-methane Chemical Properties,Uses,Production
Description
Amino-Tri-(carboxyethoxymethyl)-methane is a branched molecule that is reactive towards carboxylic acids in the presence of HATU. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Biological Activity
Amino-Tri-(carboxyethoxymethyl)-methan is a cleavable PEG-based ADC linker that can be used to synthesize antibody drug conjugates (ADCs). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
target
| PEGs
| Cleavable
|
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai Send Pharmaceutical Technology Co., Ltd. | 021-58088081 Q3252066219 | danping@shsendpharm.com | China | 3136 | 55 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
| Zhengzhou Huiju Chemical Co., Ltd. | 0371-55900031 18137872243 | 2853979815@qq.com | China | 10007 | 55 |
| Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28819 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4824 | 58 |
View Lastest Price from Amino-Tri-(carboxyethoxymethyl)-methane manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-29 | Amino-Tri-(carboxyethoxymethyl)-methane
174362-95-9
|
US $0.00 / mg | 500mg | >95.00% | 500mg | Xian confluore Biological Technology Co., Ltd. |
-
- Amino-Tri-(carboxyethoxymethyl)-methane
174362-95-9
- US $0.00 / mg
- >95.00%
- Xian confluore Biological Technology Co., Ltd.