2-(4-Bromo-1H-pyrazol-1-yl)ethanol
- CAS No.
- 214614-81-0
- Chemical Name:
- 2-(4-Bromo-1H-pyrazol-1-yl)ethanol
- Synonyms
- Albb-003673;AKOS B024012;AKOS PAO-0968;ART-CHEM-BB B024012;4-bromo-1H-Pyrazole-1-ethanol;1H-Pyrazole-1-ethanol, 4-bromo-;2-(4-BROMO-PYRAZOL-1-YL)-ETHANOL;1-(2-hydroxyethyl)-4-bromopyazole;4-BroMo-1-(2-hydroxyethyl)pyrazole;2-(4-Bromo-1H-pyrazol-1-yl)ethanol
- CBNumber:
- CB2496731
- Molecular Formula:
- C5H7BrN2O
- Molecular Weight:
- 191.03
- MDL Number:
- MFCD06804929
- MOL File:
- 214614-81-0.mol
- MSDS File:
- SDS
| Boiling point | 299.2±20.0 °C(Predicted) |
|---|---|
| Density | 1.74±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 14.30±0.10(Predicted) |
| Appearance | White to yellow Solid |
| Comptox DTXSID | DTXSID20586331 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314-H227-H290 |
| Precautionary statements | P501-P210-P234-P264-P280-P370+P378-P390-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P403+P235-P406-P405 |
| Hazard Codes | Xi |
| HazardClass | IRRITANT |
| HS Code | 2933199090 |
2-(4-Bromo-1H-pyrazol-1-yl)ethanol price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS1733 | 4-Bromo-1-(2-hydroxyethyl)pyrazole 95% | 214614-81-0 | 1g | $74 | 2026-06-04 | Buy |
| Activate Scientific | AS1733 | 4-Bromo-1-(2-hydroxyethyl)pyrazole 95% | 214614-81-0 | 5g | $302 | 2026-06-04 | Buy |
| Matrix Scientific | 030915 | 2-(4-Bromo-1H-pyrazol-1-yl)ethanol | 214614-81-0 | 500.00mg | $52 | 2026-05-18 | Buy |
| aablocks | AA003KRQ | 4-Bromo-1-(2-hydroxyethyl)pyrazole 97% | 214614-81-0 | 100mg | $12 | 2026-05-28 | Buy |
| aablocks | AA003KRQ | 4-Bromo-1-(2-hydroxyethyl)pyrazole 97% | 214614-81-0 | 250mg | $14 | 2026-05-28 | Buy |
2-(4-Bromo-1H-pyrazol-1-yl)ethanol Chemical Properties, Uses, Production
Uses
2-(4-Bromo-1H-pyrazol-1-yl)ethanol, can be used in the synthesis of more complex pharmaceutical compounds, such as 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-ethanol (T302675).
Synthesis
2075-45-8
540-51-2
214614-81-0
General procedure for the synthesis of 1-(2-hydroxyethyl)-4-bromopyrazole from 4-bromopyrazole and 2-bromoethanol: 4-bromopyrazole (400 mg, 2.72 mmol), potassium iodide (671 mg, 4.04 mmol), potassium hydroxide (290 mg, 5.2 mmol), and 2-bromoethanol (625 mg, 5.0 mmol) were reacted in an ethanol (10 mL) The mixture in a microwave reactor was placed in a microwave reactor and reacted at 155 °C for 8 hours. Upon completion of the reaction, the reaction mixture was cooled to room temperature, filtered to remove insoluble material, followed by rotary evaporation to remove the solvent. The residue was dissolved in 20 mL of ethyl acetate, washed with 20 mL of water, dried over anhydrous sodium sulfate, and concentrated to give 1-(2-hydroxyethyl)-4-bromopyrazole (0.45 g, 86% yield) as a yellow oil.
References
[1] Patent: WO2008/88881, 2008, A1. Location in patent: Page/Page column 47
[2] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 21, p. 6804 - 6820
2-(4-Bromo-1H-pyrazol-1-yl)ethanol Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| ZHIWE CHEMTECH CO LTD | 021-20221225 13917446399 | zwchem@163.com | China | 516 | 61 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44567 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Accela ChemBio Co.,Ltd. | 4000665055 | marketing@accelachem.com | China | 10969 | 64 |
| ZEROSCHEM.CO.,LTD. | 10-61256048 13810278579; | sales@zeroschem.com | China | 1410 | 59 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Wuhan Chemduro Pharm Tech Co. Ltd. | 18040571231/1402788087 | China | 1972 | 58 | |
| ShangHai KenEn Chemical Technology Co., Ltd. | 13120367189;18621755571 | mychess007@163.com | China | 1994 | 55 |
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