NAPHTHOQUINE PHOSPHATE
- CAS No.
- 173531-58-3
- Chemical Name:
- NAPHTHOQUINE PHOSPHATE
- Synonyms
- NAPHTHOQUINE PHOSPHATE;Naphathoquine Phosphate;NAPHTHOQUINE PHOSPHATE USP/EP/BP;Naphthalene phosphoric acid phenol quinoline;4-[(7-Chloro-4-quinolinyl)amino]-2-[[(tert-butyl)amino]methyl]-5,6,7,8-tetrahydro-1-naphthalenol phosphate;1-Naphthalenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[[(1,1-dimethylethyl)amino]methyl]-5,6,7,8-tetrahydro-, phosphate (1:2) (salt)
- CBNumber:
- CB2517511
- Molecular Formula:
- C24H31ClN3O5P
- Molecular Weight:
- 507.95
- MDL Number:
- MFCD25541748
- MOL File:
- 173531-58-3.mol
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
|---|---|
| solubility | Soluble in DMSO |
| form | Powder |
| color | Light yellow to yellow |
| FDA UNII | M6M6AP4KAH |
NAPHTHOQUINE PHOSPHATE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ApexBio Technology | A3641 | Naphthoquinephosphate | 173531-58-3 | 10mg | $61 | 2021-12-16 | Buy |
| ChemScene | CS-0739 | Naphthoquine(phosphate) 99.71% | 173531-58-3 | 10mg | $72 | 2021-12-16 | Buy |
| ChemScene | CS-0739 | Naphthoquine(phosphate) 99.71% | 173531-58-3 | 50mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-0739 | Naphthoquine(phosphate) 99.71% | 173531-58-3 | 100mg | $180 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611920 | Naphthoquine phosphate | 173531-58-3 | 50mg | $229.5 | 2021-12-16 | Buy |
NAPHTHOQUINE PHOSPHATE Chemical Properties,Uses,Production
Biological Activity
malaria remains a disease of devastating global impact, killing more than 800,000 people every year-the vast majority being children under the age of 5. naphthoquine phosphate is a antimalarial drug developed in china.
in vitro
naphthoquine phosphate showed promising antimalaria acitivities against various p. falciparum strains. moreover, previoius study highlighted that naphthoquine did not lose potency when tested against chloroquine resistant strains [1].
in vivo
in an study aiming to investigate the antimalarial activity of naphthoquine phosphate combined with artemisinine against plasmodium knowlesi in rhesus monkey, it was found that the combination of naphthoquine phosphate and artemisinine was superior to the single component and the optimum proportion in the combination is 1 : 2.5 in treating p. knowlesi infection in monkeys [2].
target
malaria
IC 50
0.1-5.2 nm for various p. falciparum strains [1]
References
[1] delves m, plouffe d, scheurer c, meister s, wittlin s, winzeler ea, sinden re, leroy d. the activities of current antimalarial drugs on the life cycle stages of plasmodium: a comparative study with human and rodent parasites. plos med. 2012;9(2):e1001169.
[2] wang jy, ding db, li gf, zhao jh. therapeutic efficacy of naphthoquine phosphate combined with artemisinine against plasmodium knowlesi. zhongguo ji sheng chong xue yu ji sheng chong bing za zhi. 2008;26(6):442-4.
[3] tun t, tint hs, lin k, kyaw tt, myint mk, khaing w, tun zw. efficacy of oral single dose therapy with artemisinin-naphthoquine phosphate in uncomplicated falciparum malaria. acta trop. 2009;111(3):275-8.
NAPHTHOQUINE PHOSPHATE Preparation Products And Raw materials
Raw materials
Preparation Products
NAPHTHOQUINE PHOSPHATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8806 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12830 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30236 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22787 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| PT CHEM GROUP LIMITED | +86-85511178; +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
View Lastest Price from NAPHTHOQUINE PHOSPHATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-29 | NAPHTHOQUINE PHOSPHATE
173531-58-3
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Weibang Biotechnology Co., Ltd | |
 |
2024-11-18 | Naphthoquine phosphate
173531-58-3
|
US $75.00-57.00 / mg | 99.59% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-18 | Naphthoquine phosphate
173531-58-3
|
US $75.00-57.00 / mg | 99.59% | 10g | TargetMol Chemicals Inc. |
-
- NAPHTHOQUINE PHOSPHATE
173531-58-3
- US $10.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- Naphthoquine phosphate
173531-58-3
- US $75.00-57.00 / mg
- 99.59%
- TargetMol Chemicals Inc.
-
- Naphthoquine phosphate
173531-58-3
- US $75.00-57.00 / mg
- 99.59%
- TargetMol Chemicals Inc.