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Sodium taurodeoxycholate hydrate

CAS No.
207737-97-1
Chemical Name:
Sodium taurodeoxycholate hydrate
Synonyms
5β12αsodium 2-[[(3αSodium taurodeoxycholate, ≥99%;SODIUM TAURODEOXYCHOLATE HYDRATE;N-(Deoxycholyl)taurine sodium salt;SODIUM TAURODEOXYCHOLATE HYDRATE BIO;Taurodeoxycholic acid sodium hydrate;Taurodeoxycholic Acid-[d6] Sodium Salt;2H6]-Taurodeoxycholic Acid Sodium Salt
CBNumber:
CB2547459
Molecular Formula:
C26H48NNaO7S
Molecular Weight:
541.72
MDL Number:
MFCD00149238
MOL File:
207737-97-1.mol
MSDS File:
SDS
Last updated:2024-11-25 20:05:57

Sodium taurodeoxycholate hydrate Properties

Melting point 168 °C (dec.)(lit.)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility H2O: soluble0.5M, clear, colorless to faintly yellow
form A crystalline solid
color White to off-white
BRN 3901204

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H315-H335
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
WGK Germany  3
HS Code  29242998
NFPA 704
0
2 0

Sodium taurodeoxycholate hydrate price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T0557 Sodium taurodeoxycholate hydrate BioXtra, ≥97% (TLC) 207737-97-1 1g $84.7 2024-03-01 Buy
Sigma-Aldrich T0557 Sodium taurodeoxycholate hydrate BioXtra, ≥97% (TLC) 207737-97-1 5g $247 2024-03-01 Buy
Cayman Chemical 15935 Taurodeoxycholic Acid (sodium salt hydrate) ≥95% 207737-97-1 1g $44 2024-03-01 Buy
Cayman Chemical 15935 Taurodeoxycholic Acid (sodium salt hydrate) ≥95% 207737-97-1 5G $109 2024-03-01 Buy
Cayman Chemical 15935 Taurodeoxycholic Acid (sodium salt hydrate) ≥95% 207737-97-1 25g $426 2024-03-01 Buy
Product number Packaging Price Buy
T0557 1g $84.7 Buy
T0557 5g $247 Buy
15935 1g $44 Buy
15935 5G $109 Buy
15935 25g $426 Buy

Sodium taurodeoxycholate hydrate Chemical Properties,Uses,Production

Description

Sodium taurodeoxycholate hydrate is a bile salt-related, anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. It has also been used in a study to investigate polymorphic behavior in protein surfactant mixtures.
Sodium taurodeoxycholate hydrate has been used in a study to assess the effect of submicellar concentrations of bile salts on the lipid bilayer membrane. It has also been used in a study to investigate polymorphic behavior in protein-surfactant mixtures.

Uses

A hydrate form of sodium taurodeoxycholate (T009005), a steroid which rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.

General Description

Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.

Purification Methods

The Na salt is dissolved in the smallest volume of H2O, a saturated solution of aqueous NaCl/Et2O is added and the mixture is stored at 0o for 24hours. Then shake the mixture well, keep it in the cold for another day and filter the crystals with gentle shaking, wash them with ice-cold saturated aqueous NaCl saturated with Et2O, dry them over CaCl2 and extract them with absolute EtOH. Add ~10mL of H2O to the solid followed by enough Et2O to incipient cloudiness. Store it overnight at 0o. Add ice-cold Et2O to make 250mL, collect the crystals, wash them with Et2O then pet ether and dry them in air. The purification can be repeated with NaCl and Et2O with ~85% recovery. NB: precipitation will not occur unless enough H2O is present. Its solubility in H2O is 10%. [Cortese J Am Chem Soc 59 2532 1937.] The free acid has m 141-144o. [Norman Ark Kemi 8 331 1956.] It forms mixed micelles and solubilises some membrane proteins [Hajjar et al. J Biol Chem 2 5 8 192 1983]. [Beilstein 10 IV 1611.]

Sodium taurodeoxycholate hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 165)Suppliers
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BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
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Nanjing ChemLin Chemical Industry Co., Ltd.
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TargetMol Chemicals Inc.
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Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10319 58

View Lastest Price from Sodium taurodeoxycholate hydrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Sodium taurodeoxycholate pictures 2024-11-25 Sodium taurodeoxycholate
207737-97-1
US $499.00-399.00 / kg 0.1kg 99%min 1ton
Sodium taurodeoxycholate hydrate pictures 2024-11-22 Sodium taurodeoxycholate hydrate
207737-97-1
US $0.00 / G 500G 97%min 30kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Sodium taurodeoxycholate hydrate pictures 2024-11-19 Sodium taurodeoxycholate hydrate
207737-97-1
US $29.00 / mg 95% 10g TargetMol Chemicals Inc.

Sodium taurodeoxycholate hydrate Spectrum

2-[[(3alpha,5beta,12alpha)-3,12-Dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid monosodium salt hydrate TAURODEOXYCHOLIC ACID SODIUM SIGMAULTRA 2-([3α,12α-dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid Taurodeoxycholic acid hydrate sodium salt, 2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid N-(Deoxycholyl)taurine sodium salt, Taurodeoxycholic acid sodium salt, 3α,12α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt Sodium taurodeoxycholate hydrate,2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid, Taurodeoxycholic acid sodium salt hydrate Ethanesulfonic acid,2-[[(3a,5b,12a)-3,12-dihydroxy-24-oxocholan-24-yl]aMino]-, sodiuM salt, hydrate (1:1:) 3α,12α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt N-(Deoxycholyl)taurine sodium salt 2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid, Taurodeoxycholic acid sodium salt hydrate SODIUM TAURODEOXYCHOLATE HYDRATE BIO SODIUM TAURODEOXYCHOLATE HYDRATE Taurodeoxycholic Acid sodium salt hydrat Taurodeoxycholic Acid-[d6] Sodium Salt Taurodeoxycholic acid sodium hydrate Sodium Taurodeoxycholate Hydrate See T009005 Sodium taurodeoxycholate, ≥99% Taurodeoxycholic Acid-D4 Sodium Salt DiHydrateQ: What is Taurodeoxycholic Acid-D4 Sodium Salt DiHydrate Q: What is the CAS Number of Taurodeoxycholic Acid-D4 Sodium Salt DiHydrate Q: What is the storage condition of Taurodeoxycholic Acid-D4 Sodium Salt DiHydrate Q: What are the applications of Taurodeoxycholic Acid-D4 Sodium Salt DiHydrate Sodium Taurodeoxycholate HydrateQ: What is Sodium Taurodeoxycholate Hydrate Q: What is the CAS Number of Sodium Taurodeoxycholate Hydrate Q: What is the storage condition of Sodium Taurodeoxycholate Hydrate Q: What are the applications of Sodium Taurodeoxycholate Hydrate sodium 2-{[(3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonate hydrate Sodium Taurodeoxycholate Hydrate (STDC Hydrate) extrapure, 97% Sodium 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonate hydrate (1:1:?) Sodium 2-((R)-4-((3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethanesulfonate xhydrate 2H6]-Taurodeoxycholic Acid Sodium Salt 12α sodium 2-[[(3α Taurodeoxycholic Acid-[d6] Sodium Salt in Methanol Taurodeoxycholic Acid Sodium Salt Hydrate in Methanol 207737-97-1 C26H46NO6SxH2ONa