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MD-224

MD-224 structure

CAS No.: 2136247-12-4

Chemical Name:: MD-224

Synonyms: MD-224;11,E1/E2/E3 Enzyme,leukemia,PROTACs,E2 conjugating enzyme,MD 224;MD224,inhibit,PROTAC,Ubiquitin activating enzyme,Ubiquitin ligase,Inhibitor,MDM-2/p53,cancer,MD-224,E1 activating enzyme,Ubiquitin conjugating enzyme,E3 ligating enzyme,RS4;Dispiro[cyclohexane-1,2'-pyrrolidine-3',3''-[3H]indole]-5'-carboxamide, 6''-chloro-4'-(3-chloro-2-fluorophenyl)-N-[4-[[[5-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-4-yl]-4-pentyn-1-yl]amino]carbonyl]phenyl]-1'',2''-dihydro-2''-oxo-, (3'R,4'S,5'R)-

CBNumber:: CB25821231

Molecular Formula:: C48H43Cl2FN6O6

Molecular Weight:: 889.81

MDL Number:: MFCD32201043

MOL File:: 2136247-12-4.mol

Last updated:2024-07-02 08:55:04

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MD-224 Properties

Density	1.49±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO:100.0(Max Conc. mg/mL);112.38(Max Conc. mM)
form	Solid
pka	10.67±0.40(Predicted)
color	Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

MD-224 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0082057	MD-224 99.74%	2136247-12-4	5mg	$190	2021-12-16	Buy
ChemScene	CS-0082057	MD-224 99.74%	2136247-12-4	10mg	$350	2021-12-16	Buy
ChemScene	CS-0082057	MD-224 99.74%	2136247-12-4	25mg	$650	2021-12-16	Buy
ChemScene	CS-0082057	MD-224 99.74%	2136247-12-4	50mg	$950	2021-12-16	Buy
ChemScene	CS-0082057	MD-224 99.74%	2136247-12-4	100mg	$1750	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0082057	5mg	$190	Buy
CS-0082057	10mg	$350	Buy
CS-0082057	25mg	$650	Buy
CS-0082057	50mg	$950	Buy
CS-0082057	100mg	$1750	Buy

MD-224 Preparation Products And Raw materials

Raw materials

Preparation Products

MD-224 Suppliers

Global( 23)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185	sales-cpd@caerulumpharma.com	China	3434	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7892	56
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4197	55
Shanghai YuanYe Biotechnology Co., Ltd.	021-61312847; 18021002903	3008007409@qq.com	China	27322	60
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9863	58
Fan De(Beijing) Biotechnology Co., Ltd.	15911056312	liming@bio-fount.com	China	9730	58
Jilin Province Woda Biotechnology Co., Ltd.	13504435624	1927928688@qq.com	China	1366	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
InvivoChem	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	56
Shanghai Lollane Biological Technology Co.,Ltd.	55
Shanghai YuanYe Biotechnology Co., Ltd.	60
Shanghai Chaolan Chemical Technology Center	58
Fan De(Beijing) Biotechnology Co., Ltd.	58
Jilin Province Woda Biotechnology Co., Ltd.	58

MD-224 Dispiro[cyclohexane-1,2'-pyrrolidine-3',3''-[3H]indole]-5'-carboxamide, 6''-chloro-4'-(3-chloro-2-fluorophenyl)-N-[4-[[[5-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-4-yl]-4-pentyn-1-yl]amino]carbonyl]phenyl]-1'',2''-dihydro-2''-oxo-, (3'R,4'S,5'R)- 11,E1/E2/E3 Enzyme,leukemia,PROTACs,E2 conjugating enzyme,MD 224 MD224,inhibit,PROTAC,Ubiquitin activating enzyme,Ubiquitin ligase,Inhibitor,MDM-2/p53,cancer,MD-224,E1 activating enzyme,Ubiquitin conjugating enzyme,E3 ligating enzyme,RS4 2136247-12-4 C48H43Cl2FN6O6