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Tubulysin
- CAS No.
- 1943604-24-7
- Chemical Name:
- Tubulysin
- Synonyms
- Tubulysin
- CBNumber:
- CB25821271
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD32201124
- MOL File:
- Mol file
Last updated:2024-07-02 08:55:04
Tubulysin Chemical Properties,Uses,Production
Description
Tubulysin family of secondary metabolites are originally isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. These compounds are potent microtubule destabilizing agents with IC50 values in the picomolar range against many cancer cell lines, including those with multidrug resistant properties. Tubulysins have limited therapeutic utility due to severe toxicity, so Tubulysins are ideal candidates to be incorporated into molecule drug conjugate (SMDC) delivery system[1].
References
[1]. Leamon CP, et al. Prostate-Specific Membrane Antigen-Specific Antitumor Activity of a Self-Immolative Tubulysin Conjugate. Bioconjug Chem. 2019 Jun 19;30(6):1805-1813.
Tubulysin Preparation Products And Raw materials
Raw materials
Preparation Products
Tubulysin Suppliers
Global( 5)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| ChemExpress | +86-021-58950125 +86-021-58950125; | info@chemexpress.com | China | 780 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| Shanghai Haoyuan Chemexpress Co., Ltd. | 021-51870955 | info@chemexpress.com | China | 817 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903882 15990081639 | sunshixuan@huidabiotech.com | China | 3656 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| ChemExpress | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 58 |
| Shanghai Haoyuan Chemexpress Co., Ltd. | 58 |
| Zhejiang Huida Biotech Co., LTD | 58 |
Tubulysin
1943604-24-7