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BRD-IN-3

CAS No.
2351938-32-2
Chemical Name:
BRD-IN-3
Synonyms
BRD-IN-3;BRD IN 3,BRDIN3;4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-[[(3R,5R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methyl-3-piperidinyl]amino]-3,5-dihydro-3-methyl-
CBNumber:
CB25821291
Molecular Formula:
C21H25N5O3
Molecular Weight:
395.45
MDL Number:
MFCD32067976
MOL File:
2351938-32-2.mol
Last updated:2023-05-21 10:59:17

BRD-IN-3 Properties

storage temp. Store at -20°C
solubility Soluble in DMSO

BRD-IN-3 Chemical Properties,Uses,Production

Description

BRD-IN-3 ((R,R)-36n) is a highly potent PCAF bromodomain (BRD) inhibitor, with an IC50 of 7 nM. BRD-IN-3 also exhibits activity against GCN5 and FALZ[1]. IC50: PCAF BRD[1].

References

[1]. Huang L, et al. Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain. J Med Chem. 2019 May 9;62(9):4526-4542.

BRD-IN-3 Preparation Products And Raw materials

Raw materials

Preparation Products

BRD-IN-3 Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19698 58
BRD-IN-3 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-[[(3R,5R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methyl-3-piperidinyl]amino]-3,5-dihydro-3-methyl- BRD IN 3,BRDIN3 2351938-32-2