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PD-1-IN-22

PD-1-IN-22 Structure
PD-1-IN-22 structure
CAS No.
2349372-98-9
Chemical Name:
PD-1-IN-22
Synonyms
PD-1-IN-22;PD 1 IN 22,PD1IN22;1,2,4-Triazolo[4,3-a]pyridine-8-carboxamide, N-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]-6-[[(2-hydroxyethyl)amino]methyl]-
CBNumber:
CB25821392
Molecular Formula:
C25H25N5O4
Molecular Weight:
459.5
MDL Number:
MFCD32067983
MOL File:
2349372-98-9.mol
Last updated:2024-11-03 11:32:31
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PD-1-IN-22 Properties

storage temp. Store at -20°C
solubility Soluble in DMSO

PD-1-IN-22 Chemical Properties,Uses,Production

Description

PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor with an IC50 of 92.3 nM[1]. IC50: 92.3 nM (programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction)[1]

PD-1-IN-22 dose-dependently elevates IFN-γ secretion in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells[1].

References

[1]. Qin M, et al. Discovery of [1,2,4]Triazolo[4,3- a]pyridines as Potent Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction. J Med Chem. 2019 May 9;62(9):4703-4715.

PD-1-IN-22 Preparation Products And Raw materials

Raw materials

Preparation Products

PD-1-IN-22 Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32070 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38463 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9729 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19711 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
Fan De(Beijing) Biotechnology Co., Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58

View Lastest Price from PD-1-IN-22 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PD-1-IN-22 pictures 2024-11-02 PD-1-IN-22
2349372-98-9
 US $117.00-269.00 / mg 98.64% 10g TargetMol Chemicals Inc.
PD-1-IN-22 pictures 2024-11-02 PD-1-IN-22
2349372-98-9
 US $117.00-269.00 / mg 98.64% 10g TargetMol Chemicals Inc.
  • PD-1-IN-22 pictures
  • PD-1-IN-22
    2349372-98-9
  • US $117.00-269.00 / mg
  • 98.64%
  • TargetMol Chemicals Inc.
  • PD-1-IN-22 pictures
  • PD-1-IN-22
    2349372-98-9
  • US $117.00-269.00 / mg
  • 98.64%
  • TargetMol Chemicals Inc.

PD-1-IN-22 Spectrum

PD-1-IN-22(2349372-98-9)1HNMR
PD-1-IN-22 1,2,4-Triazolo[4,3-a]pyridine-8-carboxamide, N-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]-6-[[(2-hydroxyethyl)amino]methyl]- PD 1 IN 22,PD1IN22 2349372-98-9