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2-Thiothymidine

2-Thiothymidine structure

CAS No.: 28585-51-5

Chemical Name:: 2-Thiothymidine

Synonyms: 2-THIOTHYMIDINE;Thymidine, 2-thio-;2-Thio-2'-deoxythymidine;2'-deoxy-5-methyl-2-thiouridine;1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone;1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one;1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one;1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one

CBNumber:: CB2693213

Molecular Formula:: C10H14N2O4S

Molecular Weight:: 258.29

MDL Number:: MFCD03788706

MOL File:: 28585-51-5.mol

MSDS File:: SDS

Last updated:2024-10-28 16:48:35

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2-Thiothymidine Properties

form	Solid
color	White to off-white
InChI	InChI=1S/C10H14N2O4S/c1-5-3-12(10(17)11-9(5)15)8-2-6(14)7(4-13)16-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,17)/t6-,7+,8+/m0/s1
InChIKey	PISWNSOQFZRVJK-XLPZGREQSA-N
SMILES	OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=S)C[C@@H]1O

2-Thiothymidine price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	T375288	2-Thiothymidine	28585-51-5	5mg	$150	2021-12-16	Buy
Usbiological	296443	2-Thiothymidine	28585-51-5	10mg	$359	2021-12-16	Buy
Biosynth Carbosynth	NT02914	2-Thiothymidine	28585-51-5	10mg	$75	2021-12-16	Buy
Biosynth Carbosynth	NT02914	2-Thiothymidine	28585-51-5	25mg	$125	2021-12-16	Buy
American Custom Chemicals Corporation	NUC0003081	2-THIOTHYMIDINE 98.00%	28585-51-5	10MG	$173.25	2021-12-16	Buy

Product number	Packaging	Price	Buy
T375288	5mg	$150	Buy
296443	10mg	$359	Buy
NT02914	10mg	$75	Buy
NT02914	25mg	$125	Buy
NUC0003081	10MG	$173.25	Buy

2-Thiothymidine Chemical Properties,Uses,Production

Uses

2-Thiothymidine is a mRNA therapy used for treatment of ornithine transcarbamylase deficiency.

Application

2-Thiothymidine is a hydrogen bond donor and acceptor that can be used as a substitute for thymine in the synthesis of DNA. 2-Thiothymidine has been shown to have successful in vivo treatment against bladder cancer and skin cells, as well as photochemical properties. It has been shown to inhibit the growth of prostate cancer cells by inhibiting DNA synthesis. 2-Thiothymidine binds to dna duplexes and polymerase chain reactions, which are important for replication of DNA. This drug also inhibits replication by preventing intramolecular hydrogen bonds from forming. 2-Thiothymidine is a nucleoside analog that is substituted for thymine during DNA synthesis. It inhibits the growth of prostate cancer cells by inhibiting DNA synthesis. It binds to dna duplexes and polymerase chain reactions, which are important for replication of DNA. This drug also inhibits replication by preventing intramolecular hydrogen bonds from forming.

Definition

2-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc

2-Thiothymidine Preparation Products And Raw materials

Raw materials

Preparation Products

2-Thiothymidine Suppliers

Global( 41)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
PANNACEAN(HENAN)MEDICINE SCIENCE TECHNOLOGIES LTD	0371-55159968 18137130222	haifeng.zhang@pannacean.com	China	715	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49476	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	China	52849	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	9983	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
Hunan Jibang Biological Technology Co., LTD	+8613776644403	sales02@kingboomtech.com	China	1804	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38631	58

Supplier	Advantage
PANNACEAN(HENAN)MEDICINE SCIENCE TECHNOLOGIES LTD	58
BOC Sciences	58
CONIER CHEM AND PHARMA LIMITED	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
Hefei Hirisun Pharmatech Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
NewCan Biotech Limited	58
Nextpeptide Inc	58
Hunan Jibang Biological Technology Co., LTD	58
TargetMol Chemicals Inc.	58

View Lastest Price from 2-Thiothymidine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-10-28	2-Thiothymidine 28585-51-5	US $0.00-0.00 / mg			10g	TargetMol Chemicals Inc.

2-Thiothymidine
28585-51-5
US $0.00-0.00 / mg
TargetMol Chemicals Inc.

28585-51-5(2-Thiothymidine)Related Search:

Nucleoside 1-(2-HYDROXY-ETHOXYMETHYL)-2-THIOXO-2,3-DIHYDRO-1H-PYRIMIDIN-4-ONE 5-METHYL-2-THIOURIDINE 2-THIOTHYMIDINE-5'-TRIPHOSPHATE LITHIUM SALT 2-Thiothymidine

2-THIOTHYMIDINE 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one 2-Thio-2'-deoxythymidine 2'-deoxy-5-methyl-2-thiouridine 1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone Thymidine, 2-thio- 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one 28585-51-5