Tetraethyleneglycol monododecyl ether
- CAS No.
- 5274-68-0
- Chemical Name:
- Tetraethyleneglycol monododecyl ether
- Synonyms
- TETRAETHYLENE GLYCOL MONODODECYL ETHER;3,6,9,12-Tetraoxatetracosan-1-ol;BRIJ 30;C12E4;Polyoxyl 4 lauryl ether;POLYOXYETHYLENE 4 LAURYL ETHER;3,6,9,12-Tetraoxa-1-tetracosanol;BRIJ(R) 30;BRIJ(TM) 30;n-dodecyl-PEG4-OH
- CBNumber:
- CB2706807
- Molecular Formula:
- C20H42O5
- Molecular Weight:
- 362.54
- MDL Number:
- MFCD00043063
- MOL File:
- 5274-68-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 14°C |
|---|---|
| Boiling point | 185°C/0.2mmHg(lit.) |
| Density | 0.946 g/mL at 20 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | 2-8°C |
| pka | 14.36±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
| Odor | at 100.00%. mild alcoholic |
| BRN | 1791369 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Cosmetics Ingredients Functions |
ANTISTATIC SURFACTANT - EMULSIFYING SURFACTANT - CLEANSING FRAGRANCE |
| InChI | 1S/C20H42O5/c1-2-3-4-5-6-7-8-9-10-11-13-22-15-17-24-19-20-25-18-16-23-14-12-21/h21H,2-20H2,1H3 |
| InChIKey | WPMWEFXCIYCJSA-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCOCCOCCOCCOCCO |
| LogP | 4.204 (est) |
| CAS DataBase Reference | 5274-68-0(CAS DataBase Reference) |
| Indirect Additives used in Food Contact Substances | POLYOXYETHYLENE (4) LAURYL ETHER |
| FDA 21 CFR | 178.3520 |
| EWG's Food Scores | 1-3 |
| FDA UNII | 6HQ855798J |
| EPA Substance Registry System | Tetraethylene glycol monododecyl ether (5274-68-0) |
| Cosmetics Info | Laureth-4 |
| UNSPSC Code | 41116107 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335-H410 |
| Precautionary statements | P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi,N |
| Risk Statements | 36/37/38-50/53-52/53 |
| Safety Statements | 26-36-61-60 |
| RIDADR | UN 3082 9/PG 3 |
| WGK Germany | 2 |
| RTECS | MD0875000 |
| F | 3 |
| TSCA | TSCA listed |
| HS Code | 34029000 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Aquatic Acute 1 Aquatic Chronic 1 Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
Tetraethyleneglycol monododecyl ether price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 86694 | Tetraethylene glycol monododecyl ether non-ionic | 5274-68-0 | 1ml | $189 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1372424 | Polyoxyl 4 lauryl ether United States Pharmacopeia (USP) Reference Standard | 5274-68-0 | 1ml | $192 | 2026-04-30 | Buy |
| TCI Chemical | T0769 | Tetraethylene Glycol Monododecyl Ether >98.0%(GC) | 5274-68-0 | 5mL | $359 | 2021-12-16 | Buy |
| ChemScene | CS-0152178 | PEG 4 lauryl ether ≥95% | 5274-68-0 | 1g | $43 | 2026-06-04 | Buy |
| ChemScene | CS-0152178 | PEG 4 lauryl ether ≥95% | 5274-68-0 | 5g | $96 | 2026-06-04 | Buy |
Tetraethyleneglycol monododecyl ether Chemical Properties, Uses, Production
Synthesis

General synthetic method: Under argon protection, iodoalkane (1 eq.) was added to a DMF (40 mL) solution containing triethylene glycol or tritetraethylene glycol (1 eq.). The mixture was cooled to 0 °C, and sodium hydride (1.5 eq. 60% in mineral oil) was added. The mixture was stirred for 2 h, quenched with water, and extracted with ethyl acetate (20 mL × 2). The ethyl acetate phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated to obtain the crude product. The crude product was purified by silica gel column chromatography (ethyl acetate-n-hexane). The sample was immediately used for the next reaction.
The synthesis of lauryl ether-4 was carried out using the general synthetic method described above. Tetraethylene glycol (2 mL, 11.59 mmol) was reacted with 1-iodododecane (4.42 g, 11.59 mmol) and sodium hydride (0.70 g, 17.38 mmol) to give lauryl ether-4 (2.18 g, 6.02 mmol, yield 52%), a colorless oil; Rf = 0.41 (ethyl acetate-n-hexane 3:2).Chemical Properties
white solid or colourless liquid
Uses
Tetraethylene Glycol Monododecyl Ether is a well-characterized and non-ionic surfactant.
Definition
ChEBI: Tetraethylene glycol monododecyl ether is a poly(ethylene glycol).
Tetraethyleneglycol monododecyl ether Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Minruida Technology Co., Ltd. | 010-82387566 | sales@mreda.com.cn | China | 19323 | 58 |
| Tianjin Exceedbio Technology Co., Ltd. | 022-87899679 13034388368 | exceedbio@yeah.net | China | 41 | 55 |
| Suzhou Greet Medical Technology Co., Ltd. | 0512-62384765 13701544574 | renwei@great-chem.cn | China | 79 | 58 |
| Hubei Zhonglong Kangsheng fine chemical Co.,Ltd | 027-83850125 15927542930 | 3321236220@qq.com | China | 955 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16307 | 64 |
View Latest Price from Tetraethyleneglycol monododecyl ether manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-20 | Tetraethyleneglycol monododecyl ether
5274-68-0
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
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2026-03-20 | Tetraethyleneglycol monododecyl ether
5274-68-0
|
$10.00 | 1kg | 99% | 100 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
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2025-05-23 | Tetraethyleneglycol monododecyl ether
5274-68-0
|
$45.00 | 1kg | 99% | 20 tons | Hebei Zhuanglai Chemical Trading Co Ltd |
-

- Tetraethyleneglycol monododecyl ether
5274-68-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-

- Tetraethyleneglycol monododecyl ether
5274-68-0
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- Tetraethyleneglycol monododecyl ether
5274-68-0
- $45.00
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd









