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ChemicalBook >> CAS DataBase List >>4-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYLAMINO]-6-[2-[[2-(METHYLSULFONYL)ETHYL]AMINOMETHYL]-4-THIAZOLYL]QUINAZOLINE DIHYDROCHLORIDE

4-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYLAMINO]-6-[2-[[2-(METHYLSULFONYL)ETHYL]AMINOMETHYL]-4-THIAZOLYL]QUINAZOLINE DIHYDROCHLORIDE

4-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYLAMINO]-6-[2-[[2-(METHYLSULFONYL)ETHYL]AMINOMETHYL]-4-THIAZOLYL]QUINAZOLINE DIHYDROCHLORIDE Structure
4-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYLAMINO]-6-[2-[[2-(METHYLSULFONYL)ETHYL]AMINOMETHYL]-4-THIAZOLYL]QUINAZOLINE DIHYDROCHLORIDE structure
CAS No.
1173023-85-2
Chemical Name:
4-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYLAMINO]-6-[2-[[2-(METHYLSULFONYL)ETHYL]AMINOMETHYL]-4-THIAZOLYL]QUINAZOLINE DIHYDROCHLORIDE
Synonyms
GW 583340 DIHYDROCHLORIDE;4-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYLAMINO]-6-[2-[[2-(METHYLSULFONYL)ETHYL]AMINOMETHYL]-4-THIAZOLYL]QUINAZOLINE DIHYDROCHLORIDE;N-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYL]-6-[2-[[[2-(METHYLSULFONYL)ETHYL]AMINO]METHYL]-4-THIAZOLYL]-4-QUINAZOLINAMINE DIHYDROCHLORIDE
CBNumber:
CB2754989
Molecular Formula:
C28H27Cl3FN5O3S2
Molecular Weight:
671.03
MDL Number:
MFCD07370137
MOL File:
Mol file
Last updated:2023-06-30 15:45:59
Request For Quotation

4-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYLAMINO]-6-[2-[[2-(METHYLSULFONYL)ETHYL]AMINOMETHYL]-4-THIAZOLYL]QUINAZOLINE DIHYDROCHLORIDE Properties

Melting point 259.8-262.4 °C(lit.)
storage temp. 2-8°C
solubility DMSO: 9 mg/mL
form solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

4-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYLAMINO]-6-[2-[[2-(METHYLSULFONYL)ETHYL]AMINOMETHYL]-4-THIAZOLYL]QUINAZOLINE DIHYDROCHLORIDE price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich G3545 GW583340 dihydrochloride ≥97% (HPLC), solid 1173023-85-2 1mg $226 2024-03-01 Buy
Sigma-Aldrich G3545 GW583340 dihydrochloride ≥97% (HPLC), solid 1173023-85-2 5mg $994 2022-05-15 Buy
Tocris 2239 GW583340 dihydrochloride ≥97%(HPLC) 1173023-85-2 50 $656 2021-12-16 Buy
Tocris 2239 GW583340 dihydrochloride ≥97%(HPLC) 1173023-85-2 10 $160 2021-12-16 Buy
TRC G931543 GW583340 dihydrochloride 1173023-85-2 1mg $130 2021-12-16 Buy
Product number Packaging Price Buy
G3545 1mg $226 Buy
G3545 5mg $994 Buy
2239 50 $656 Buy
2239 10 $160 Buy
G931543 1mg $130 Buy

4-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYLAMINO]-6-[2-[[2-(METHYLSULFONYL)ETHYL]AMINOMETHYL]-4-THIAZOLYL]QUINAZOLINE DIHYDROCHLORIDE Chemical Properties,Uses,Production

Uses

GW 583340 dihydrochloride is a potent inhibitor of EGFR/ErbB2 reducing multi-drug resistance in cancer cells. Used in breast cancer treatment.

storage

Desiccate at +4°C

4-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYLAMINO]-6-[2-[[2-(METHYLSULFONYL)ETHYL]AMINOMETHYL]-4-THIAZOLYL]QUINAZOLINE DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

4-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYLAMINO]-6-[2-[[2-(METHYLSULFONYL)ETHYL]AMINOMETHYL]-4-THIAZOLYL]QUINAZOLINE DIHYDROCHLORIDE Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@qq.com China 8346 55
BOC Sciences -- info@bocsci.com USA 0 65
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 4679 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9268 58
ApexBio Technology -- sales@apexbt.com United States 6254 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Hubei Yangxin Medical Technology Co., Ltd. 55
BOC Sciences 65
MedBioPharmaceutical Technology Inc 58
Nantong QuanYi Biotechnology Co., Ltd 58
RD International Technology Co., Limited 58
ApexBio Technology 58
N-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYL]-6-[2-[[[2-(METHYLSULFONYL)ETHYL]AMINO]METHYL]-4-THIAZOLYL]-4-QUINAZOLINAMINE DIHYDROCHLORIDE GW 583340 DIHYDROCHLORIDE 4-[3-CHLORO-4-[(3-FLUOROPHENYL)METHOXY]PHENYLAMINO]-6-[2-[[2-(METHYLSULFONYL)ETHYL]AMINOMETHYL]-4-THIAZOLYL]QUINAZOLINE DIHYDROCHLORIDE 1173023-85-2