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2-Chloro-5-(chloromethyl)pyridine

2-Chloro-5-(chloromethyl)pyridine Structure
2-Chloro-5-(chloromethyl)pyridine structure
CAS No.
70258-18-3
Chemical Name:
2-Chloro-5-(chloromethyl)pyridine
Synonyms
2-chloro-chloromethylpyridine;Pyridine, 2-chloro-5-(chloromethyl)-;6-Chlo;60% in DMF;AKOS MSC-0759;AURORA KA-6694;2-Chloro-5-(ch;TIMTEC-BB SBB003948;2-Chloro-5-Chloro-Me;imidacloprid impurity
CBNumber:
CB2761158
Molecular Formula:
C6H5Cl2N
Molecular Weight:
162.02
MDL Number:
MFCD00125366
MOL File:
70258-18-3.mol
MSDS File:
SDS
Last updated:2024-08-17 21:30:02
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2-Chloro-5-(chloromethyl)pyridine Properties

Melting point 37-42 °C(lit.)
Boiling point 267.08°C (rough estimate)
Density 1.4411 (rough estimate)
refractive index 1.6000 (estimate)
Flash point >230 °F
storage temp. Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Moist Crystals
pka -0.75±0.10(Predicted)
color Beige
Water Solubility Insoluble in water.
BRN 1635690
InChI InChI=1S/C6H5Cl2N/c7-3-5-1-2-6(8)9-4-5/h1-2,4H,3H2
InChIKey SKCNYHLTRZIINA-UHFFFAOYSA-N
SMILES C1(Cl)=NC=C(CCl)C=C1
CAS DataBase Reference 70258-18-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H314
Precautionary statements  P260-P280-P301+P312+P330-P301+P330+P331-P303+P361+P353-P305+P351+P338
Hazard Codes  C,Xi,F
Risk Statements  22-34-36-10
Safety Statements  26-36/37/39-45-25-36-16
RIDADR  UN 3261 8/PG 2
WGK Germany  3
Hazard Note  Corrosive/Harmful
HazardClass  LACHRYMATOR, CORROSIVE
HazardClass  8
PackingGroup  II
HS Code  29333999
NFPA 704
1
3 0

2-Chloro-5-(chloromethyl)pyridine price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 516910 2-Chloro-5-(chloromethyl)pyridine 97% 70258-18-3 5g $49.1 2024-03-01 Buy
Sigma-Aldrich 516910 2-Chloro-5-(chloromethyl)pyridine 97% 70258-18-3 25g $59.04 2024-03-01 Buy
TCI Chemical C1628 2-Chloro-5-(chloromethyl)pyridine >98.0%(GC) 70258-18-3 5g $156 2024-03-01 Buy
TCI Chemical C1628 2-Chloro-5-(chloromethyl)pyridine >98.0%(GC) 70258-18-3 25g $460 2024-03-01 Buy
Alfa Aesar L19284 2-Chloro-5-(chloromethyl)pyridine, 96% 70258-18-3 5g $41.65 2024-03-01 Buy
Product number Packaging Price Buy
516910 5g $49.1 Buy
516910 25g $59.04 Buy
C1628 5g $156 Buy
C1628 25g $460 Buy
L19284 5g $41.65 Buy

2-Chloro-5-(chloromethyl)pyridine Chemical Properties,Uses,Production

Description

2-Chloro-5-chloromethylpyridine is used for the synthesis of various pharmaceutical compounds. It can also be used for the synthesis of new neonicotinoid compounds1, having insecticidal activity. It is the raw material of pesticide products such as imidacloprid, acetamiprid as well as bactericide and herbicide2,3.

Structure

2-Chloro-5-(chloromethyl)pyridine, C6H5Cl2N, is almost planar, with an r.m.s. deviation of 0.0146 Å for all atoms except for the 5-choloromethyl Cl atom. The offset Cl atom lies above this plane with a Cl—C—C angle of 111.11 (17)°. In the crystal, mol­ecules are connected via inter­molecular C—H⋯N hydrogen bonds, forming dimers. The crystals were obtained by dissolving 2-Chloro-5-(chloromethyl)pyridine (0.2 g, 1.2 mmol) in ethanol (25 ml) and evaporating the solvent slowly at room temperature for about 5 d[1].
2-Chloro-5-(chloromethyl)pyridine

Sources

  1. https://www.alfa.com/en/catalog/L19284/
  2. https://www.trc-canada.com/product-detail/?C364715
  3. www.szqhbio.com/wap_news_detailen/id/1.htm

Chemical Properties

beige moist crystals

Uses

2-Chloro-5-(chloromethyl)pyridine is used for the synthesis of various pharmaceutical compounds. It can also be used for the synthesis of new neonicotinoid compounds.

References

[1] Zhi-Qiang Feng. “2-Chloro-5-(chloro-meth-yl)pyridine.” Acta crystallographica. Section E, Structure reports online 67 Pt 2 (2011): o366.

2-Chloro-5-(chloromethyl)pyridine synthesis

150807-86-6
70258-18-3
Synthesis of 2-Chloro-5-(chloromethyl)pyridine from Pentanenitrile, 4-chloro-4-(chloromethyl)-5-oxo-

2-Chloro-5-(chloromethyl)pyridine Preparation Products And Raw materials

Raw materials

Nicotinic acid 3-(Chloromethyl)pyridine 2-Chloro-5-trichloromethylpyridine Phosphorus pentoxide 2-Chloro-5-methylpyridine
1,3-Cyclopentadiene Pentanenitrile, 4-chloro-4-(chloromethyl)-5-oxo- Pentanamide, 4-chloro-4-(chloromethyl)-5-oxo- 2-Chloro-5-hydroxymethylpyridine (6-methoxypyridin-3-yl)methanol
5-(hydroxymethyl) pyridin-2(1H)-one N,N-Dibutylformamide Methyl 6-chloronicotinate 6-Chloronicotinic acid Cyanuric chloride

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Preparation Products

Acetamiprid 4-(6-Chloro-pyridin-3-ylMethyl)-piperazine-1-carboxylic acid tert-butyl ester, 98+% C15H22ClN3O2, MW: 311.81 2-chloro-5-(piperidin-1-ylmethyl)pyridine 2-chloro-5-[(methylthio)methyl]pyridine(SALTDATA: FREE)

2-Chloro-5-(chloromethyl)pyridine Suppliers

Global( 584)Suppliers
Supplier Tel Email Country ProdList Advantage
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
AS WATER CO., LTD.
+86-18994963526 +8618994963526 1346073549@qq.com United Kingdom 176 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5892 58
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2472 58
Nantong Guangyuan Chemicl Co,Ltd 		+undefined17712220823 admin@guyunchem.com China 615 58
hebei hongtan Biotechnology Co., Ltd 		+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 970 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3002 58
Hebei Shengyang Water Conservancy Engineering Co., Ltd. 		+8615373025980 clara@hbshengyang.com China 874 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 18777 58
Supplier Advantage
Chongqing Chemdad Co., Ltd
58
AS WATER CO., LTD.
58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Henan Bao Enluo International TradeCo.，LTD 		58
Nantong Guangyuan Chemicl Co,Ltd 		58
hebei hongtan Biotechnology Co., Ltd 		58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		58
Hebei Shengyang Water Conservancy Engineering Co., Ltd. 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58

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View Lastest Price from 2-Chloro-5-(chloromethyl)pyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-5-chloromethylpyridine pictures 2024-11-25 2-Chloro-5-chloromethylpyridine
70258-18-3
 US $30.00 / kg 1kg 99% 5000kg/week Hebei Zhuanglai Chemical Trading Co.,Ltd
2-Chloro-5-chloromethylpyridine pictures 2024-11-25 2-Chloro-5-chloromethylpyridine
70258-18-3
 US $2.00 / KG 1KG 99% 1000mt/year Jinan Finer Chemical Co., Ltd
2-Chloro-5-chloromethylpyridine pictures 2024-11-22 2-Chloro-5-chloromethylpyridine
70258-18-3
 US $30.00 / kg 1kg 98% 2000kg hebei hongtan Biotechnology Co., Ltd

2-Chloro-5-(chloromethyl)pyridine Spectrum

2-Chloro-5-chloromethylpyridine(70258-18-3)IR

70258-18-3(2-Chloro-5-(chloromethyl)pyridine)Related Search:

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2,6-DICHLORO-5-FLUORONICOTINOYL CHLORIDE 2,6-DICHLORO-3-(CHLOROMETHYL)PYRIDINE 2,3-Dichloro-5-(trichloromethyl)pyridine Difluorochloromethane 6-CHLORONICOTINOYL CHLORIDE
2,6-dichloro-3-(trichloromethyl)pyridine 2-CHLORO-5-(CHLOROMETHYL)PYRIDINE HYDROCHLORIDE 2,4-DICHLORO-5-(CHLOROMETHYL)-PYRIDINE

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2-CHLORO-5-CHLOROMETHYLPYRIDINE 90% 2-Chloro-5-ChloroMethylPyridine(Ccmp)98% 2-Chloro-5-Chloro Methyl Pyridine (Ccmp) 98% Pyridine, 2-chloro-5-(chloromethyl)- (9CI) 2-Chloro-5-chloromethylpyridine, tech., 90% imidacloprid impurity 2-CHLORO-5-(CHLOROMETHYL)PYRIDINE[FOR IMIDACLOPRID] 2-CHLORO-5-CHLOROMETHYLPYRIDINE 2-CHLORO-5-CHLOROMETHYLPYRIDINE 2-CHLORO-5-CHLOROMETHYLPYRIDINE, 90%, TECH. 2-Chlor-5-Chlormethylpyridine 2-Chloro-5-Chloro-Me (6-Chloropyridin-3-yl)Methyl chloride 2-Chloro-5-pyridylMethyl chloride 2-Chloropyridin-5-ylMethyl chloride 3-(ChloroMethyl)-6-chloropyridine 5-(ChloroMethyl)-2-chloropyridine 6-Chlo AURORA KA-6694 2,5-DICHLORO-4-METHYL-PYRIDINE 2-CHLORO-5-CHLOROMETHYLPYRIDINE AKOS MSC-0759 TIMTEC-BB SBB003948 alpha,6-Dichloro-3-picoline 2-Chloro-5-(ch 2-Chloro-5-(chloromethyl)pyridine,96% 2-CHLORO-5-CHLOROMETHYL PYRIDINE (CCMP), 60% DMF 2-Chloro-5-(chloromethyl)pyridine> 60% in DMF Pyridine, 2-chloro-5-(chloromethyl)- 2-chloro-chloromethylpyridine Fampridine Impurity 215 C11397000 2-Chloro-5-(chloromethyl)pyridine 70258-18-3 0258-18-3 BENZYL HALIDE Heterocyclic Building Blocks Halogenated Heterocycles Pyridines Chloropyridines Halopyridines Building Blocks Pharmaceutical intermediates C6Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyridines Chloropyridines Halopyridines Methyl Halides Heterocycle-Pyridine series API Intermediate Pyridine series Methyl Halides HALOMETYL Pyridine 70258-18-3