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4,4-dimethyl-2-(2-phenylpropan-2-yl)oxazo‐ line

CAS No.
874895-87-1
Chemical Name:
4,4-dimethyl-2-(2-phenylpropan-2-yl)oxazo‐ line
Synonyms
Bilastine impurity 08;4,4-dimethyl-2-(2-phenylpropan-2-yl)oxazo‐ line;4,4-dimethyl-2-(2-phenylpropan-2-yl)-4,5-dihydrooxazole;Oxazole, 4,5-dihydro-4,4-dimethyl-2-(1-methyl-1-phenylethyl)-
CBNumber:
CB28056450
Molecular Formula:
C14H19NO
Molecular Weight:
217.31
MDL Number:
MOL File:
874895-87-1.mol
Last updated:2023-05-15 10:43:56

4,4-dimethyl-2-(2-phenylpropan-2-yl)oxazo‐ line Properties

Boiling point 292.0±19.0 °C(Predicted)
Density 0.99±0.1 g/cm3(Predicted)
solubility soluble in Dichloromethane
form Oil
pka 5.79±0.70(Predicted)
color Yellow

4,4-dimethyl-2-(2-phenylpropan-2-yl)oxazo‐ line Chemical Properties,Uses,Production

Uses

4,5-Dihydro-4,4-dimethyl-2-(1-methyl-1-phenylethyl)oxazole-d6 is an intermediate used in the synthesis of Bilastine-d6 (B385002), which is labelled Bilastine. It is a novel, nonsedating H1-antihistamine developed for symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria.

4,4-dimethyl-2-(2-phenylpropan-2-yl)oxazo‐ line Preparation Products And Raw materials

Raw materials

Preparation Products

4,4-dimethyl-2-(2-phenylpropan-2-yl)oxazo‐ line Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
ANHUI WITOP BIOTECH CO., LTD
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Mianyang Vandino Pharmaceutical Technology Co., Ltd. 0816-1568120-1579 15681201579 1755695756@qq.com China 309 58
Shanghai YuZn Pharm. Technology Co.,Ltd. 15921286451; 15921286451 2010681527@qq.com China 5095 58
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 hanfangpharma@126.com China 30961 58
4,4-dimethyl-2-(2-phenylpropan-2-yl)oxazo‐ line Oxazole, 4,5-dihydro-4,4-dimethyl-2-(1-methyl-1-phenylethyl)- 4,4-dimethyl-2-(2-phenylpropan-2-yl)-4,5-dihydrooxazole Bilastine impurity 08 874895-87-1