Penbutolol
- CAS No.
- 38363-40-5
- Chemical Name:
- Penbutolol
- Synonyms
- C07416;HOE 893;HOE 893D;Betapressin;l-Penbutolol;Levopenbutol;Levopenbutolol;(S)-Penbutolol;(-)-Penbutolol;(-)-(S)-Penbutolol
- CBNumber:
- CB2875284
- Molecular Formula:
- C18H29NO2
- Molecular Weight:
- 291.43
- MDL Number:
- MOL File:
- 38363-40-5.mol
| Melting point | 68-72° |
|---|---|
| alpha | 20D -11.5° (c = 1 in methanol) |
| Boiling point | 433.43°C (rough estimate) |
| Density | 1.0344 (rough estimate) |
| refractive index | 1.5000 (estimate) |
| pka | 9.3 (1.5 mmol/l in 25% ethanol) |
| color | Crystals |
| Water Solubility | 7g/L(room temperature) |
| FDA UNII | 78W62V43DY |
Penbutolol Chemical Properties,Uses,Production
Originator
Betapressin, Hoechst , W. Germany ,1980
Uses
Anti-adrenergic (β-receptor).
Definition
ChEBI: Penbutolol is a member of ethanolamines.
Manufacturing Process
21.8 g (0.1 mol) of 1,2-epoxy-3-(2'-cyclopentylphenoxy)propane, boiling at 113°C to 115°C/0.2 mm Hg (prepared from 2-cyclopentylphenol and epichlorhydrin in the presence of alkali) were dissolved in 250 ml of ethanol; to this solution, there were added dropwise, while stirring.8.9 g (0.15 mol) of t-butylamine. The reaction mixture was stirred for 2 hours at 60°C and then the solvent and the excess t-butylamine were removed by distillation. The residue which had been purified via the aqueous hydrochloride, crystallized, after removal of the ether by evaporation, upon rubbing or inoculation and yielded, after recrystallization from n-heptane, the 1-t-butylamino-2-hydroxy3-(2'-cyclopentylphenoxy)propane which was found to melt at 69°C to 70°C.
brand name
Levatol(Schwarz Pharma).
Therapeutic Function
Beta-adrenergic blocker
Safety Profile
Poison by ingestion and intravenous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Penbutolol Preparation Products And Raw materials
Penbutolol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38632 | 58 | |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19885 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14055 | 65 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9923 | 65 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-021-61109150 | sales@tcisct.com | China | 31121 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24647 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11974 | 58 |
| 4008-099-669 | 23419001name@qq.com | CHINA | 71677 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| BOC Sciences | 65 |
| BOC Sciences | 65 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| 58 |
View Lastest Price from Penbutolol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-28 | Penbutolol
38363-40-5
|
US $1980.00-1520.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- Penbutolol
38363-40-5
- US $1980.00-1520.00 / mg
- TargetMol Chemicals Inc.