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2-hydroxy-3-(phosphonooxy)propyl palmitate

CAS No.
22002-85-3
Chemical Name:
2-hydroxy-3-(phosphonooxy)propyl palmitate
Synonyms
Einecs 244-707-4;1-Palmitoyl lysophosphatidic acid;2-hydroxy-3-(phosphonooxy)propyl palmitate;1-Palmitoyl Lysophosphatidic Acid Exclusive;Palmitic acid 2-hydroxy-3-(phosphonooxy)propyl ester;2-hydroxy-3-(phosphonooxy)propyl ester Hexadecanoic acid;Hexadecanoic acid, 2-hydroxy-3-(phosphonooxy)propyl ester;1-Palmitoyl Lysophosphatidic Acid (1-Palmitoyl LPA free acid)
CBNumber:
CB2899006
Molecular Formula:
C19H39O7P
Molecular Weight:
410.48
MDL Number:
MFCD18427958
MOL File:
22002-85-3.mol
Last updated:2024-07-02 08:55:04

2-hydroxy-3-(phosphonooxy)propyl palmitate Properties

Boiling point 560.6±60.0 °C(Predicted)
Density 1.112±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 2 mg/ml; DMSO: 2.5 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 3 mg/ml
form A crystalline solid
pka 1.82±0.10(Predicted)
color White to off-white

2-hydroxy-3-(phosphonooxy)propyl palmitate price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10010094 1-Palmitoyl Lysophosphatidic Acid ≥98% 22002-85-3 1mg $34 2023-01-06 Buy
Cayman Chemical 10010094 1-Palmitoyl Lysophosphatidic Acid ≥98% 22002-85-3 5mg $152 2023-01-06 Buy
Cayman Chemical 10010094 1-Palmitoyl Lysophosphatidic Acid ≥98% 22002-85-3 10mg $269 2023-01-06 Buy
Cayman Chemical 10010094 1-Palmitoyl Lysophosphatidic Acid ≥98% 22002-85-3 25mg $588 2023-01-06 Buy
American Custom Chemicals Corporation LIP0000657 2-HYDROXY-3-(PHOSPHONOOXY)PROPYL ESTER HEXADECANOIC ACID 95.00% 22002-85-3 5MG $500.06 2021-12-16 Buy
Product number Packaging Price Buy
10010094 1mg $34 Buy
10010094 5mg $152 Buy
10010094 10mg $269 Buy
10010094 25mg $588 Buy
LIP0000657 5MG $500.06 Buy

2-hydroxy-3-(phosphonooxy)propyl palmitate Chemical Properties,Uses,Production

Description

1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of at least five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.1,2 Additionally, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of P. aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca2+ and Mg2+.3

Definition

ChEBI: 1-palmitoylglycerol 3-phosphate is a monoacylglycerol phosphate having palmitoyl as the acyl group on O-1 and with the phosphate group on O-3. It is a conjugate acid of a 1-palmitoylglycerol 3-phosphate(2-).

References

1. Noguchi, K., Ishii, S., and Shimizu, T. Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family J. Biol. Chem. 278(28),25600-25606(2003).
2. Moolenaar, W.H. LPA: A novel lipid mediator with diverse biological actions Trends Cell Biol. 4(6),213-219(1994).
3. Krogfelt, K.A., Utley, M., Krivan, H.C., et al. Specific phospholipids enhance the activity of β-lactam antibiotics against Pseudomonas aeruginosa J. Antimicrob. Chemother. 46(3),377-384(2000).

305847-08-9
22002-85-3
Synthesis of 2-hydroxy-3-(phosphonooxy)propyl palmitate from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

2-hydroxy-3-(phosphonooxy)propyl palmitate Preparation Products And Raw materials

Raw materials

Preparation Products

2-hydroxy-3-(phosphonooxy)propyl palmitate Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Shaanxi Dideu Newmaterial Co., Ltd. 029-87576359 15353716720 1039@dideu.com China 10011 58
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 shenlinxing@macklin.cn China 29802 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 18621169109 market03@meryer.com China 27996 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 4679 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 18112977050 cb5@aikonchem.com China 10529 58
SHANGHAI ZZBIO CO., LTD. 15102117276 19921389125 tech@zzbioco.com China 12064 58
2-hydroxy-3-(phosphonooxy)propyl palmitate 1-Palmitoyl lysophosphatidic acid 2-hydroxy-3-(phosphonooxy)propyl ester Hexadecanoic acid Palmitic acid 2-hydroxy-3-(phosphonooxy)propyl ester Einecs 244-707-4 Hexadecanoic acid, 2-hydroxy-3-(phosphonooxy)propyl ester 1-Palmitoyl Lysophosphatidic Acid Exclusive 1-Palmitoyl Lysophosphatidic Acid (1-Palmitoyl LPA free acid) 22002-85-3 C19H39O7P