Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, 6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-fluoro-1'-(3,4,5,6,7,8-hexahydro-8-methyl-4-oxopyrido[2,3-d]pyrimidin-2-yl)-1-methyl-, rel-

Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, 6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-fluoro-1'-(3,4,5,6,7,8-hexahydro-8-methyl-4-oxopyrido[2,3-d]pyrimidin-2-yl)-1-methyl-, rel-

Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, 6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-fluoro-1'-(3,4,5,6,7,8-hexahydro-8-methyl-4-oxopyrido[2,3-d]pyrimidin-2-yl)-1-methyl-, rel- Structure
Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, 6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-fluoro-1'-(3,4,5,6,7,8-hexahydro-8-methyl-4-oxopyrido[2,3-d]pyrimidin-2-yl)-1-methyl-, rel- structure
CAS No.
2171388-28-4
Chemical Name:
Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, 6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-fluoro-1'-(3,4,5,6,7,8-hexahydro-8-methyl-4-oxopyrido[2,3-d]pyrimidin-2-yl)-1-methyl-, rel-
Synonyms
RK-582;Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, 6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-fluoro-1'-(3,4,5,6,7,8-hexahydro-8-methyl-4-oxopyrido[2,3-d]pyrimidin-2-yl)-1-methyl-, rel-
CBNumber:
CB29038978
Molecular Formula:
C27H35FN6O3
Molecular Weight:
510.6
MDL Number:
MOL File:
2171388-28-4.mol
Last updated:2023-03-31 09:12:58
Request For Quotation

Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, 6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-fluoro-1'-(3,4,5,6,7,8-hexahydro-8-methyl-4-oxopyrido[2,3-d]pyrimidin-2-yl)-1-methyl-, rel- Properties

Boiling point 752.7±70.0 °C(Predicted)
Density 1.44±0.1 g/cm3(Predicted)
pka 7.08±0.20(Predicted)

Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, 6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-fluoro-1'-(3,4,5,6,7,8-hexahydro-8-methyl-4-oxopyrido[2,3-d]pyrimidin-2-yl)-1-methyl-, rel- Chemical Properties,Uses,Production

Description

RK-582 is an orally efficacious spiroindolinone-based tankyrase inhibitor for the treatment of colon cancer. It exhibits a markedly improved robust tumor growth inhibition in a COLO-320DM mouse xenograft model when orally administered.

Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, 6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-fluoro-1'-(3,4,5,6,7,8-hexahydro-8-methyl-4-oxopyrido[2,3-d]pyrimidin-2-yl)-1-methyl-, rel- Preparation Products And Raw materials

Raw materials

Preparation Products

Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, 6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-fluoro-1'-(3,4,5,6,7,8-hexahydro-8-methyl-4-oxopyrido[2,3-d]pyrimidin-2-yl)-1-methyl-, rel- Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9412 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28091 58
Supplier Advantage
DC Chemicals 58
TargetMol Chemicals Inc. 58
Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, 6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-fluoro-1'-(3,4,5,6,7,8-hexahydro-8-methyl-4-oxopyrido[2,3-d]pyrimidin-2-yl)-1-methyl-, rel- RK-582 2171388-28-4 C27H35FN6O3