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Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-

CAS No.
70209-81-3
Chemical Name:
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
Synonyms
Component B1b;Ivermectin B1b;IvermectinH2B1b;avermectin H2B1b;Dihydroavermectin B1b;22,23-Dihydroavermectin B1b;22,23- dihydroavermectin B1b (Ivermectin B1b);22,23-Dihydro-34-nor-5-O-demethylavermectin A1a;DihydroaverMectin B1b, 22,23-DihydroaverMectin B1b;22,23-Dihydro-5-O-demethyl-25-de(1-methylpropyl)-25-isopropylavermectin A1a
CBNumber:
CB2918291
Molecular Formula:
C47H72O14
Molecular Weight:
861.07
MDL Number:
MFCD00866559
MOL File:
70209-81-3.mol
MSDS File:
SDS
Last updated:2024-10-23 13:36:13

Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Properties

Boiling point 934.1±65.0 °C(Predicted)
Density 1.24±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form A solid
pka 12.42±0.70(Predicted)
Stability Temperature sensitive
FDA UNII 0W28CYI3TU

SAFETY

Risk and Safety Statements

RIDADR  2588
HazardClass  6.1(a)
PackingGroup  II

Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 23824 Ivermectin B1b ≥95% 70209-81-3 500μg $311 2024-03-01 Buy
Cayman Chemical 23824 Ivermectin B1b ≥95% 70209-81-3 2.5mg $1316 2024-03-01 Buy
TRC I940825 IvermectinB1b 70209-81-3 2.5mg $1220 2021-12-16 Buy
Usbiological D3570-04A Ivermectin B1b 70209-81-3 500ug $478 2021-12-16 Buy
American Custom Chemicals Corporation API0017173 B1-BETA-IVERMECTIN COMPONENT 95.00% 70209-81-3 5MG $501.15 2021-12-16 Buy
Product number Packaging Price Buy
23824 500μg $311 Buy
23824 2.5mg $1316 Buy
I940825 2.5mg $1220 Buy
D3570-04A 500ug $478 Buy
API0017173 5MG $501.15 Buy

Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Chemical Properties,Uses,Production

Uses

Ivermectin B1b is a minor component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19.

Uses

Ivermectin B1b (dihydroavermectin B1b) is the minor component (<20%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectin/milbemycins are also potent insecticides. In vitro, the B1b (25-iso-propyl) analogue is slightly more potent than the 25-sec-butyl (B1a) analogue as an inhibitor of nematode larval development and paralysis, and also a more sensitive probe for ivermectin resistance.

Definition

ChEBI: A macrocyclic lactone that is avermectin B1b in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the minor component of ivermectin.

brand name

Stromectol (Merck).

Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 43)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
career henan chemical co
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TargetMol Chemicals Inc.
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BOC Sciences
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LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43340 58
Aladdin Scientific
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Guangzhou PI PI Biotech Inc 020-81716320 +86-13602409664 Sales@pipitech.com China 3633 55
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 18042 56
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12306 58

View Lastest Price from Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ivermectin B1b pictures 2024-10-24 Ivermectin B1b
70209-81-3
US $778.00 / μg 10g TargetMol Chemicals Inc.
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- pictures 2020-01-13 Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
70209-81-3
US $1.00 / KG 1KG 98%-99.9% 100kg Career Henan Chemical Co
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- avermectin H2B1b Component B1b 22,23-Dihydro-34-nor-5-O-demethylavermectin A1a 22,23-Dihydro-5-O-demethyl-25-de(1-methylpropyl)-25-isopropylavermectin A1a 22,23-Dihydroavermectin B1b Dihydroavermectin B1b 5-O-Demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)avermectin A1a Ivermectin B1b IvermectinH2B1b DihydroaverMectin B1b, 22,23-DihydroaverMectin B1b 22,23- dihydroavermectin B1b (Ivermectin B1b) 70209-81-3