Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
- CAS No.
- 70209-81-3
- Chemical Name:
- Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
- Synonyms
- Component B1b;Ivermectin B1b;IvermectinH2B1b;avermectin H2B1b;Dihydroavermectin B1b;22,23-Dihydroavermectin B1b;22,23- dihydroavermectin B1b (Ivermectin B1b);22,23-Dihydro-34-nor-5-O-demethylavermectin A1a;DihydroaverMectin B1b, 22,23-DihydroaverMectin B1b;22,23-Dihydro-5-O-demethyl-25-de(1-methylpropyl)-25-isopropylavermectin A1a
- CBNumber:
- CB2918291
- Molecular Formula:
- C47H72O14
- Molecular Weight:
- 861.07
- MDL Number:
- MFCD00866559
- MOL File:
- 70209-81-3.mol
- MSDS File:
- SDS
Boiling point | 934.1±65.0 °C(Predicted) |
---|---|
Density | 1.24±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble |
form | A solid |
pka | 12.42±0.70(Predicted) |
Stability | Temperature sensitive |
FDA UNII | 0W28CYI3TU |
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 23824 | Ivermectin B1b ≥95% | 70209-81-3 | 500μg | $311 | 2024-03-01 | Buy |
Cayman Chemical | 23824 | Ivermectin B1b ≥95% | 70209-81-3 | 2.5mg | $1316 | 2024-03-01 | Buy |
TRC | I940825 | IvermectinB1b | 70209-81-3 | 2.5mg | $1220 | 2021-12-16 | Buy |
Usbiological | D3570-04A | Ivermectin B1b | 70209-81-3 | 500ug | $478 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0017173 | B1-BETA-IVERMECTIN COMPONENT 95.00% | 70209-81-3 | 5MG | $501.15 | 2021-12-16 | Buy |
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Chemical Properties,Uses,Production
Uses
Ivermectin B1b is a minor component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19.
Uses
Ivermectin B1b (dihydroavermectin B1b) is the minor component (<20%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectin/milbemycins are also potent insecticides. In vitro, the B1b (25-iso-propyl) analogue is slightly more potent than the 25-sec-butyl (B1a) analogue as an inhibitor of nematode larval development and paralysis, and also a more sensitive probe for ivermectin resistance.
Definition
ChEBI: A macrocyclic lactone that is avermectin B1b in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the minor component of ivermectin.
brand name
Stromectol (Merck).
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29811 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19741 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
Guangzhou PI PI Biotech Inc | 020-81716320 +86-13602409664 | Sales@pipitech.com | China | 3633 | 55 |
ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 18042 | 56 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12306 | 58 |
View Lastest Price from Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-10-24 | Ivermectin B1b
70209-81-3
|
US $778.00 / μg | 10g | TargetMol Chemicals Inc. | ||||
2020-01-13 | Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
70209-81-3
|
US $1.00 / KG | 1KG | 98%-99.9% | 100kg | Career Henan Chemical Co |
- Ivermectin B1b
70209-81-3
- US $778.00 / μg
- TargetMol Chemicals Inc.
- Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
70209-81-3
- US $1.00 / KG
- 98%-99.9%
- Career Henan Chemical Co