Fmoc-L-Asn(EDA-N3)-OH
- CAS No.
- 2616562-74-2
- Chemical Name:
- Fmoc-L-Asn(EDA-N3)-OH
- Synonyms
- Fmoc-Asn(EDA-N3)-OH;Fmoc-L-Asn(EDA-N3)-OH;N2-Fmoc-N4-(2-azidoethyl)-L-asparagine
- CBNumber:
- CB29687420
- Molecular Formula:
- C21H21N5O5
- Molecular Weight:
- 423.43
- MDL Number:
- MOL File:
- 2616562-74-2.mol
Fmoc-L-Asn(EDA-N3)-OH price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Iris Biotech GmbH | FAA8605 | Fmoc-L-Asn(EDA-N3)-OH | 2616562-74-2 | 500mg | $218.7 | 2021-12-16 | Buy |
| Iris Biotech GmbH | FAA8605 | Fmoc-L-Asn(EDA-N3)-OH | 2616562-74-2 | 1g | $340.2 | 2021-12-16 | Buy |
| Iris Biotech GmbH | FAA8605 | Fmoc-L-Asn(EDA-N3)-OH | 2616562-74-2 | 5G | $1215 | 2021-12-16 | Buy |
| Iris Biotech GmbH | FAA8605 | Fmoc-L-Asn(EDA-N3)-OH | 2616562-74-2 | 25g | $4860 | 2021-12-16 | Buy |
Fmoc-L-Asn(EDA-N3)-OH Chemical Properties,Uses,Production
Uses
Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
References
[1] Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789. DOI:10.1080/17460441.2019.1614910
Fmoc-L-Asn(EDA-N3)-OH Preparation Products And Raw materials
Raw materials
Preparation Products
Fmoc-L-Asn(EDA-N3)-OH Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
| Suzhou Derivative Biotechnology Co., Ltd. | 13915541704 | 2436368162@qq.com | China | 350 | 58 |
| Shanghai Huici Pharmaceutical Technology Co., LTD | 19372841038 19372841038 | lixing@pharmahuici.com | China | 469 | 58 |
| Affinity（Wuhan）Ltd. | 15841022315 | sales@affinitytech.cn | China | 3000 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 4008675858 | sales1@amateksci.com | China | 3868 | 58 |
| Shanghai Yanfen Biochemical Technology Co.,LTD | 13611955358 13611955358 | yanfen2024@126.com | China | 1880 | 58 |