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Burnettramic Acid A

Burnettramic Acid A structure

CAS No.: 2334483-46-2

Chemical Name:: Burnettramic Acid A

Synonyms: Burnettramic Acid A;(2Z,6R,7aS)-tetrahydro-6-hydroxy-2-[(2S,4R,12E,15R,19R)-1,15,19-trihydroxy-26-(β-D-mannopyranosyloxy)-2,4-dimethyl-14-hexacosen-1-ylidene]-1H-pyrrolizine-1,3(2H)-dione;1H-Pyrrolizine-1,3(2H)-dione, tetrahydro-6-hydroxy-2-[(2S,4R,12E,115R,19R)-1,15,19-trihydroxy-26-(β-D-mannopyranosyloxy)-2,4-dimethyl-14-hexacosen-1-ylidene]-, (2Z,6R,7aS)-

CBNumber:: CB29739327

Molecular Formula:: C41H71NO12

Molecular Weight:: 770.01

MDL Number:: MFCD33021177

MOL File:: 2334483-46-2.mol

Last updated:2023-05-21 10:59:17

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Burnettramic Acid A Properties

Boiling point	952.1±65.0 °C(Predicted)
Density	1.23±0.1 g/cm3(Predicted)
storage temp.	-20°C
form	A solid
pka	4.50±1.00(Predicted)

Burnettramic Acid A Chemical Properties,Uses,Production

Biological Activity

Burnettramic acid A is a fungal metabolite originally isolated from A. burnettii that has diverse biological activities.1 It is active against B. subtilis, S. aureus, C. albicans, and S. cerevisiae (IC50s = 2.3, 5.9, 0.5, and 0.2 μg/ml, respectively). Burnettramic acid A is cytotoxic to NS-1 murine myeloma cells but not neonatal foreskin fibroblasts (IC50s = 13.8 and >100 μg/ml, respectively).

References

1.Li, H., Gilchrist, C.L.M., Lacey, H.J., et al.Discovery and heterologous biosynthesis of the burnettramic acids: Rare PKS-NRPS-derived bolaamphiphilic pyrrolizidinediones from an Australian fungus, Aspergillus burnettiiOrg. Lett.21(5)1287-1291(2019)

Burnettramic Acid A Preparation Products And Raw materials

Raw materials

Preparation Products

Burnettramic Acid A Suppliers

Global( 8)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14055	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9804	58
ChemeGen 中国	18818260767	2625930290@qq.com	China	6973	58
Shanghai Saikerui Biotechnology Co. , Ltd.	021-58000709 15900491054	info@scrbio.com	China	9502	58
Shanghai Weiyite Biotechnology Co., Ltd	15317051735	zhaojing@wytsci.com	China	9199	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	cindy.huang@synzest.com	China	12000	58

Supplier	Advantage
BOC Sciences	65
Shanghai EFE Biological Technology Co., Ltd.	58
ChemeGen 中国	58
Shanghai Saikerui Biotechnology Co. , Ltd.	58
Shanghai Weiyite Biotechnology Co., Ltd	58
Nanjing Shizhou Biology Technology Co.,Ltd	58

Burnettramic Acid A 1H-Pyrrolizine-1,3(2H)-dione, tetrahydro-6-hydroxy-2-[(2S,4R,12E,115R,19R)-1,15,19-trihydroxy-26-(β-D-mannopyranosyloxy)-2,4-dimethyl-14-hexacosen-1-ylidene]-, (2Z,6R,7aS)- (2Z,6R,7aS)-tetrahydro-6-hydroxy-2-[(2S,4R,12E,15R,19R)-1,15,19-trihydroxy-26-(β-D-mannopyranosyloxy)-2,4-dimethyl-14-hexacosen-1-ylidene]-1H-pyrrolizine-1,3(2H)-dione 2334483-46-2