ChemicalBook >> CAS DataBase List >>1-Naphthalenecarboxylic acid, 2-[[[2-[(1Z)-3-(dimethylamino)-1-propen-1-yl]-4-fluorophenyl]sulfonyl]amino]-5,6,7,8-tetrahydro-

1-Naphthalenecarboxylic acid, 2-[[[2-[(1Z)-3-(dimethylamino)-1-propen-1-yl]-4-fluorophenyl]sulfonyl]amino]-5,6,7,8-tetrahydro-

CAS No.
904680-01-9
Chemical Name:
1-Naphthalenecarboxylic acid, 2-[[[2-[(1Z)-3-(dimethylamino)-1-propen-1-yl]-4-fluorophenyl]sulfonyl]amino]-5,6,7,8-tetrahydro-
Synonyms
A-849519;1-Naphthalenecarboxylic acid, 2-[[[2-[(1Z)-3-(dimethylamino)-1-propen-1-yl]-4-fluorophenyl]sulfonyl]amino]-5,6,7,8-tetrahydro-
CBNumber:
CB310100526
Molecular Formula:
C22H25FN2O4S
Molecular Weight:
432.51
MDL Number:
MOL File:
904680-01-9.mol
Last updated:2024-10-23 13:36:13

1-Naphthalenecarboxylic acid, 2-[[[2-[(1Z)-3-(dimethylamino)-1-propen-1-yl]-4-fluorophenyl]sulfonyl]amino]-5,6,7,8-tetrahydro- Properties

Boiling point 593.1±60.0 °C(Predicted)
Density 1.337±0.06 g/cm3(Predicted)
pka 3.37±0.20(Predicted)

1-Naphthalenecarboxylic acid, 2-[[[2-[(1Z)-3-(dimethylamino)-1-propen-1-yl]-4-fluorophenyl]sulfonyl]amino]-5,6,7,8-tetrahydro- Chemical Properties,Uses,Production

Description

A-849519 is a reversible inhibitor of MetAP2 that has demonstrated anti-angiogenesis and anticancer activity in a number of in vitro and in vivo models. In this study, we evaluated the anticancer activity of A-849519 in a modified Dunning model of androgen-independent prostate cancer and compared its efficacy with TNP-470, an established MetAP2 inhibitor.

1-Naphthalenecarboxylic acid, 2-[[[2-[(1Z)-3-(dimethylamino)-1-propen-1-yl]-4-fluorophenyl]sulfonyl]amino]-5,6,7,8-tetrahydro- Preparation Products And Raw materials

Raw materials

Preparation Products

1-Naphthalenecarboxylic acid, 2-[[[2-[(1Z)-3-(dimethylamino)-1-propen-1-yl]-4-fluorophenyl]sulfonyl]amino]-5,6,7,8-tetrahydro- Suppliers

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TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19863 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19711 58

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A-849519 pictures 2024-10-24 A-849519
904680-01-9
US $2780.00-2120.00 / mg 10g TargetMol Chemicals Inc.
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  • A-849519
    904680-01-9
  • US $2780.00-2120.00 / mg
  • TargetMol Chemicals Inc.
1-Naphthalenecarboxylic acid, 2-[[[2-[(1Z)-3-(dimethylamino)-1-propen-1-yl]-4-fluorophenyl]sulfonyl]amino]-5,6,7,8-tetrahydro- A-849519 904680-01-9