Thiocyanic acid, 2-(3,4-dihydroxyphenyl)-2-oxoethyl ester (9CI)
- CAS No.
- 101714-41-4
- Chemical Name:
- Thiocyanic acid, 2-(3,4-dihydroxyphenyl)-2-oxoethyl ester (9CI)
- Synonyms
- BIX;BiP inducer X;BIX >=98% (HPLC);BiP protein Inducer X;Thiocyanic acid 3,4-dihydroxyphenacyl ester;2-(Cyanosulfanyl)-1-(3,4-dihydroxyphenyl)ethan-1-one;2-(3,4-Dihydroxyphenyl)-2-oxoethyl ester thiocyanic acid;Thiocyanic acid, 2-(3,4-dihydroxyphenyl)-2-oxoethyl ester;Thiocyanic acid, 2-(3,4-dihydroxyphenyl)-2-oxoethyl ester (9CI);GRP78,Apoptosis,BiP,Inhibitor,inhibit,GRP94,BiP inducer X,stress,neurons,calreticulin
- CBNumber:
- CB31060509
- Molecular Formula:
- C9H7NO3S
- Molecular Weight:
- 209.22
- MDL Number:
- MFCD22415334
- MOL File:
- 101714-41-4.mol
- MSDS File:
- SDS
| Melting point | 127 °C |
|---|---|
| Boiling point | 517℃ |
| Density | 1.476 |
| Flash point | 267℃ |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble20mg/mL, clear |
| form | powder |
| pka | 7.54±0.20(Predicted) |
| color | white to beige |
| InChI | InChI=1S/C9H7NO3S/c10-5-14-4-9(13)6-1-2-7(11)8(12)3-6/h1-3,11-12H,4H2 |
| InChIKey | SVFLBLCWKKQKDW-UHFFFAOYSA-N |
| SMILES | S(CC(C1=CC=C(O)C(O)=C1)=O)C#N |
Thiocyanic acid, 2-(3,4-dihydroxyphenyl)-2-oxoethyl ester (9CI) price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1073 | BIX ≥98% (HPLC) | 101714-41-4 | 5mg | $118 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1073 | BIX ≥98% (HPLC) | 101714-41-4 | 25mg | $476 | 2024-03-01 | Buy |
| Tocris | 5375 | BIX ≥98%(HPLC) | 101714-41-4 | 50 | $357 | 2021-12-16 | Buy |
| Tocris | 5375 | BIX ≥98%(HPLC) | 101714-41-4 | 10 | $85 | 2021-12-16 | Buy |
| TRC | B591768 | BIX | 101714-41-4 | 5mg | $65 | 2021-12-16 | Buy |
Thiocyanic acid, 2-(3,4-dihydroxyphenyl)-2-oxoethyl ester (9CI) Chemical Properties,Uses,Production
Uses
BIX has been used in cell viability assay.
Definition
ChEBI: 2-(3,4-dihydroxyphenyl)-2-oxoethyl thiocyanate is a member of the class of thiocyanates that is 3,4-dihydroxyacetophenone in which one of the methyl hydrogens has been replaced by the sulfur of a cyanosulfanediyl (-SC#N) group. It has been found to induce the expression of the endoplasmic reticulum chaperone protein GRP78 (78 kDa glucose-regulated protein, BiP, a highly conserved member of the 70 kDa heat shock protein family) leading to an attenuation of the unfolded protein response. It protects neuronal cells and retinal cells from endoplasmic reticulum (ER)-stress induced cell death. It is a member of thiocyanates, an aromatic ketone and a member of catechols.
Biochem/physiol Actions
BIX (BiP protein inducer X) induces the expression of the endoplasmic reticulum chaperone protein GRP78 (glucose regulated protein 78, BiP) leading to an attenuation of the unfolded protein response. BIX protects neuronal cells and retinal cells from ER-stress induced cell death.
Thiocyanic acid, 2-(3,4-dihydroxyphenyl)-2-oxoethyl ester (9CI) Preparation Products And Raw materials
Thiocyanic acid, 2-(3,4-dihydroxyphenyl)-2-oxoethyl ester (9CI) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38632 | 58 | |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
| Adamas Reagent, Ltd. | 400-6009262 16621234537 | chenyj@titansci.com | China | 14103 | 59 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10266 | 58 |
| Modachem Shanghai Co., Ltd | +86 (0)21 51320687 51371369 1744605818 | China | 1578 | 58 | |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9793 | 50 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
View Lastest Price from Thiocyanic acid, 2-(3,4-dihydroxyphenyl)-2-oxoethyl ester (9CI) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | BiP inducer X
101714-41-4
|
US $39.00-128.00 / mg | 90% | 10g | TargetMol Chemicals Inc. |
-
- BiP inducer X
101714-41-4
- US $39.00-128.00 / mg
- 90%
- TargetMol Chemicals Inc.