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ChemicalBook >> CAS DataBase List >>Benzeneacetamide, 2-chloro-6-fluoro-N-[3-(4-fluorophenyl)-4-(4-pyrimidinyl)-5-isoxazolyl]-

Benzeneacetamide, 2-chloro-6-fluoro-N-[3-(4-fluorophenyl)-4-(4-pyrimidinyl)-5-isoxazolyl]-

Benzeneacetamide, 2-chloro-6-fluoro-N-[3-(4-fluorophenyl)-4-(4-pyrimidinyl)-5-isoxazolyl]- Structure
Benzeneacetamide, 2-chloro-6-fluoro-N-[3-(4-fluorophenyl)-4-(4-pyrimidinyl)-5-isoxazolyl]- structure
CAS No.
897644-83-6
Chemical Name:
Benzeneacetamide, 2-chloro-6-fluoro-N-[3-(4-fluorophenyl)-4-(4-pyrimidinyl)-5-isoxazolyl]-
Synonyms
AKP-001;AKP 001,AKP001;Benzeneacetamide, 2-chloro-6-fluoro-N-[3-(4-fluorophenyl)-4-(4-pyrimidinyl)-5-isoxazolyl]-
CBNumber:
CB310683278
Molecular Formula:
C21H13ClF2N4O2
Molecular Weight:
426.8
MDL Number:
MFCD30533337
MOL File:
897644-83-6.mol
Last updated:2025-04-18 09:51:59
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Benzeneacetamide, 2-chloro-6-fluoro-N-[3-(4-fluorophenyl)-4-(4-pyrimidinyl)-5-isoxazolyl]- Properties

Boiling point 592.9±50.0 °C(Predicted)
Density 1.438±0.06 g/cm3(Predicted)
pka 11.46±0.70(Predicted)
FDA UNII M4VHS5O48Z

Benzeneacetamide, 2-chloro-6-fluoro-N-[3-(4-fluorophenyl)-4-(4-pyrimidinyl)-5-isoxazolyl]- Chemical Properties,Uses,Production

Uses

AKP-001 is an inhibitor of p38 mitogen-activated protein kinase (p38 MAPK). AKP-001 can inhibit the production of inflammatory cytokines and can be used for research in rheumatoid arthritis and inflammatory bowel disease[1].

References

[1] Hasumi K, et al. Design and synthesis of 5-[(2-chloro-6-fluorophenyl)acetylamino]-3-(4-fluorophenyl)-4-(4-pyrimidinyl)isoxazole (AKP-001), a novel inhibitor of p38 MAP kinase with reduced side effects based on the antedrug concept. Bioorg Med Chem. 2014 Aug 1;22(15):4162-76. DOI:10.1016/j.bmc.2014.05.045

Benzeneacetamide, 2-chloro-6-fluoro-N-[3-(4-fluorophenyl)-4-(4-pyrimidinyl)-5-isoxazolyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzeneacetamide, 2-chloro-6-fluoro-N-[3-(4-fluorophenyl)-4-(4-pyrimidinyl)-5-isoxazolyl]- Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19727 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 58

View Lastest Price from Benzeneacetamide, 2-chloro-6-fluoro-N-[3-(4-fluorophenyl)-4-(4-pyrimidinyl)-5-isoxazolyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AKP-001 pictures 2024-11-07 AKP-001
897644-83-6
 US $1520.00-2500.00 / mg 99.92% 10g TargetMol Chemicals Inc.
  • AKP-001 pictures
  • AKP-001
    897644-83-6
  • US $1520.00-2500.00 / mg
  • 99.92%
  • TargetMol Chemicals Inc.
Benzeneacetamide, 2-chloro-6-fluoro-N-[3-(4-fluorophenyl)-4-(4-pyrimidinyl)-5-isoxazolyl]- AKP-001 AKP 001,AKP001 897644-83-6