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DX3-213B

CAS No.
2749555-66-4
Chemical Name:
DX3-213B
Synonyms
DX3-213B
CBNumber:
CB311047336
Molecular Formula:
C20H28F2N2O5S2
Molecular Weight:
478.57
MDL Number:
MOL File:
2749555-66-4.mol
Last updated:2024-07-02 08:55:04

DX3-213B Properties

solubility DMF:2.0(Max Conc. mg/mL);4.18(Max Conc. mM)
DMSO:3.0(Max Conc. mg/mL);6.27(Max Conc. mM)
Ethanol:2.0(Max Conc. mg/mL);4.18(Max Conc. mM)
form A crystalline solid
color White to off-white

DX3-213B Chemical Properties,Uses,Production

Description

DX3-213B is a potent Oxidative Phosphorylation Inhibitor (MIA PaCa-2 GI50 = 11 nM) for the Treatment of Pancreatic Cancer. DX3-213B disrupts adenosine triphosphate (ATP) generation, inhibits complex I function, and results in the growth inhibition of pancreatic cancer cells in the low nanomolar range. Importantly, the oral administration of DX3-213B resulted in significant in vivo efficacy in a pancreatic cancer syngeneic model without obvious toxicity.

DX3-213B Preparation Products And Raw materials

Raw materials

Preparation Products

DX3-213B Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3135 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52924 58
Guangzhou Younan Technology Co., Ltd 020-82000279 18988968278 sales@ubiochem.com China 4297 58
Nantong Hi-Future Biotechnology Co., Ltd 18051384581 sales@chemhifuture.com China 2995 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24644 58
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2611 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58

DX3-213B Spectrum

DX3-213B 2749555-66-4