HUMAN IGG
- CAS No.
- Chemical Name:
- HUMAN IGG
- Synonyms
- IGG;HUMAN IGG;IGG, HUMAN;IMMUNOGLOBULIN G;IGG, INTACT HUMAN;IGG HUMAN CONTROL;HUMAN IGG, INTACT;HUMAN IGG, PLASMA;HUMAN IGG (NORMAL);Rabbit IgG Protein
- CBNumber:
- CB3111747
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00163923
- MOL File:
- Mol file
HUMAN IGG price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 140764 | Immunoglobulin G | 200ul | $406 | 2021-12-16 | Buy | |
| Usbiological | 140769 | Immunoglobulin G | 200ul | $412 | 2021-12-16 | Buy | |
| Usbiological | 140761 | Immunoglobulin G | 200ul | $415 | 2021-12-16 | Buy | |
| Usbiological | 140759 | Immunoglobulin G | 200ul | $418 | 2021-12-16 | Buy | |
| Usbiological | 140765 | Immunoglobulin G | 200ul | $452 | 2021-12-16 | Buy |
HUMAN IGG Chemical Properties,Uses,Production
Uses
Purified human IgG may be used as a reference antigen, standard, blocking agent, or coating protein in a variety of immunoassays including ELISA, dot immunobinding, Western immunoblotting, immunodiffusion, and immunoelectrophoresis. Other applications include starting materials for the preparation of immunogens and solid phase immunoadsorbents. Technical grade human IgG may be used as an economical alternative to the reagent grade immunoglobulins, in applications where high purity is not required. IgG from human serum was used as ELISA standard in various studies. A concentration range of 200 μg/ml to 1 mg/ml of human IgG was used for blocking in flow cytometry.
General Description
IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections
Human IgG is purified from normal human serum by precipitation and gel filtration techniques.
Biochem/physiol Actions
IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Clinical Use
IgG (Fc=γ) participates in precipitation reactions,toxin neutralizations, and complement fixation. IgG isthe major (70%) human Ig. The Fab tip fixes antigen, andthe Fc fragment can fix complement to yield agglutinationor lysis. IgG is the only immunoglobulin that crosses thetransplacental barrier and the neonatal stomach, so it providesmaternal protection. IgG constitutes about 75% of thetotal Ab in the circulation. It is present at a concentration ofabout 15 mg/mL and has a half-life of 3 weeks, the longestof any of the Ab types. The light chains of IgG can possesseither κ or λ variants. These slight differences in structureare called isotypes, and the phenomenon is termed isotypicvariation.
HUMAN IGG Preparation Products And Raw materials
Raw materials
Preparation Products
HUMAN IGG Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973186 4009686088 | 3193328036@qq.com | China | 18352 | 68 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10036 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 18768175414 | gaojun@univ-bio.com | China | 24998 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 8305 | 58 |
| Wuhan Peptide Core Biotechnology Co., Ltd | 027-65317797 13667154760 | 1096814016@qq.com | China | 9753 | 58 |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | market@aladdin-e.com | China | 48467 | 58 |