ChemicalBook >> CAS DataBase List >>5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione

5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione

5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione structure

CAS No.: 764667-64-3

Chemical Name:: 5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione

Synonyms: ethylidene);Sitagliptin-9;Sitagliptin Impurity 96;5-(1-Hydroxy-2-(2,4,5-trifluorophenyl);5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)et;5-[1-hydroxy-2-92,4,5-trifluorophenyl0ethylidene]-2,2-dimethyl;5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimeth...;5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione;5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-diMethyl-1,3-dioxane-4,6-dion;1,3-Dioxane-4,6-dione,5-[1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-diMethyl-

CBNumber:: CB31120915

Molecular Formula:: C14H11F3O5

Molecular Weight:: 316.23

MDL Number:: MFCD12407134

MOL File:: 764667-64-3.mol

Last updated:2023-05-31 14:19:17

Request For Quotation

5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione Properties

Melting point	117 °C (decomp)
Boiling point	489.0±45.0 °C(Predicted)
Density	1.462±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form	Solid
pka	4.50±1.00(Predicted)
color	White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	H971700	5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione	764667-64-3	1g	$185	2021-12-16	Buy
Medical Isotopes, Inc.	59081	5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione	764667-64-3	1g	$650	2021-12-16	Buy
AK Scientific	Z1748	5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione	764667-64-3	1g	$71	2021-12-16	Buy
Chemenu	CM181663	5-(1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%	764667-64-3	25g	$153	2021-12-16	Buy
Crysdot	CD12035301	5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 97%	764667-64-3	25g	$166	2021-12-16	Buy

Product number	Packaging	Price	Buy
H971700	1g	$185	Buy
59081	1g	$650	Buy
Z1748	1g	$71	Buy
CM181663	25g	$153	Buy
CD12035301	25g	$166	Buy

5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione Chemical Properties,Uses,Production

Chemical Properties

White to Off-white Solid.

Uses

5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is an impurity of the DPP-IV inhibitor Sitagliptin (S491000).

Application

5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene] is an intermediate for the synthesis of sitagliptin. Sitagliptin is a new type of anti-type II diabetes drug approved by the FDA and the first dipeptidyl peptidase-IV inhibitor drug for the treatment of type II diabetes.

5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione Preparation Products And Raw materials

Raw materials

Preparation Products

Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate (Z)-Methyl 3-aMino-4-(2,4,5-trifluorophenyl)but-2-enoate Benzenebutanoicacid,b-aMino-2,4,5-trifluoro-,Methylester,(bR)-

5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione Suppliers

Global( 102)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-+86-371-66670886	info@dakenam.com	China	19805	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21628	55
Anqing Chico Pharmaceutical Co., Ltd.	15380796838	chloewu@chicopharm.cn	CHINA	340	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29858	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49732	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17365	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15395	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52849	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3148	58

Supplier	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Anqing Chico Pharmaceutical Co., Ltd.	58
career henan chemical co	58
Standardpharm Co. Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
AFINE CHEMICALS LIMITED	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hangzhou Huarong Pharm Co., Ltd.	58

View Lastest Price from 5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2023-05-31	5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione 764667-64-3	US $30.00-28.00 / Kg	1Kg	99.0% up	50 tons per month	Xinxiang Hongqi District Houyuan Trading Co.,Ltd
	2019-09-03	5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione 764667-64-3	US $7.00 / KG	1KG	99%	JD 714	Career Henan Chemical Co

5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione
764667-64-3
US $30.00-28.00 / Kg
99.0% up
Xinxiang Hongqi District Houyuan Trading Co.,Ltd

5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione
764667-64-3
US $7.00 / KG
99%
Career Henan Chemical Co

764667-64-3(5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione)Related Search:

Sitagliptin Impurity 28 Sitagliptin Impurity 46 Sitagliptin Impurity 77 Sitagliptin impurity 5 Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate

ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate 2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE Sitagliptin Impurity 34 2,4,5-TRIFLUOROBENZYL CHLORIDE (R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate

Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,Methylester,(bR)- Sitagliptin Sitagliptin Impurity 14 Sitagliptin Defuoro IMpurity 5 Sitagliptin DeaMino IMpurity 1

(S)-Sitagliptin Phosphate 2,2,2-TRIFLUORO-N'-(TRIFLUOROACETYL)ACETOHYDRAZIDE (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione

1of4

5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-diMethyl-1,3-dioxane-4,6-dion 5-[1-hydroxy-2-92,4,5-trifluorophenyl0ethylidene]-2,2-dimethyl 1,3-Dioxane-4,6-dione,5-[1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-diMethyl- 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)-4,6-dionethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione 5-(1-Hydroxy-2-(2,4,5-trifluorophenyl) ethylidene) Sitagliptin Impurity 96 Sitagliptin impurity 42/Sitagliptin Dioxo Impurity/5-(1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl- 1,3-dioxane-4,6-dione Sitagliptin-9 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimeth... 5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione 764667-64-3 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)et 5-(1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione (Sitagliptin Impurity) 764667-64-3 Aromatics Heterocycles Impurities Intermediates