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ChemicalBook >> CAS DataBase List >>2-Propen-1-one, 1-[4-[8-[[3-methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]phenyl]amino]pyrimido[5,4-d]pyrimidin-2-yl]-1-piperazinyl]-

2-Propen-1-one, 1-[4-[8-[[3-methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]phenyl]amino]pyrimido[5,4-d]pyrimidin-2-yl]-1-piperazinyl]-

2-Propen-1-one, 1-[4-[8-[[3-methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]phenyl]amino]pyrimido[5,4-d]pyrimidin-2-yl]-1-piperazinyl]- Structure
2-Propen-1-one, 1-[4-[8-[[3-methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]phenyl]amino]pyrimido[5,4-d]pyrimidin-2-yl]-1-piperazinyl]- structure
CAS No.
2682003-36-5
Chemical Name:
2-Propen-1-one, 1-[4-[8-[[3-methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]phenyl]amino]pyrimido[5,4-d]pyrimidin-2-yl]-1-piperazinyl]-
Synonyms
BI-4142;2-Propen-1-one, 1-[4-[8-[[3-methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]phenyl]amino]pyrimido[5,4-d]pyrimidin-2-yl]-1-piperazinyl]-;1-{4-[8-({3-methyl-4-[(1-methyl-1H-1,3-benzodiazol-5-yl)oxy]phenyl}amino)pyrimido[5,4-d][1,3]diazin-2-yl]piperazin-1-yl}prop-2-en-1-one
CBNumber:
CB311899337
Molecular Formula:
C28H27N9O2
Molecular Weight:
521.57
MDL Number:
MOL File:
2682003-36-5.mol
Last updated:2024-09-08 20:25:27
Request For Quotation

2-Propen-1-one, 1-[4-[8-[[3-methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]phenyl]amino]pyrimido[5,4-d]pyrimidin-2-yl]-1-piperazinyl]- Properties

Boiling point 784.9±70.0 °C(Predicted)
Density 1.39±0.1 g/cm3(Predicted)
pka 5.24±0.10(Predicted)
form Solid
color Light yellow to yellow

2-Propen-1-one, 1-[4-[8-[[3-methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]phenyl]amino]pyrimido[5,4-d]pyrimidin-2-yl]-1-piperazinyl]- Chemical Properties,Uses,Production

Description

BI-4142 is a potent, highly selective and orally active HER2 inhibitor with an IC50= 5 nM. BI-4142 showed efficacy against HER2 exon 20 insertion-driven tumors, while preserving EGFR wt signaling.

2-Propen-1-one, 1-[4-[8-[[3-methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]phenyl]amino]pyrimido[5,4-d]pyrimidin-2-yl]-1-piperazinyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Propen-1-one, 1-[4-[8-[[3-methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]phenyl]amino]pyrimido[5,4-d]pyrimidin-2-yl]-1-piperazinyl]- Suppliers

Global( 26)Suppliers
Supplier Tel Email Country ProdList Advantage
HangZhou RunYan Pharma Technology Co.,LTD. 		+86-18882027439 +86-18882027439 sales2@runyanpharma.com China 304 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32836 60
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10522 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Hubei Zhongshan Medical Technology Co., Ltd 027-61907345 13397111514 w13397111514@163.com China 1010 58
Jinan Chuanbei Biotechnology Co., Ltd 18654547380; 15269175648 qingyan7590@163.com China 21 58
Houxu Chemical (Shandong) Co., Ltd 18295613325 2026425403@qq.com China 18 58
Jinan shenlikang chemical technology co. LTD 0531-86092839 13153040268 2425815073@qq.com China 253 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3466 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4309 55
Supplier Advantage
HangZhou RunYan Pharma Technology Co.,LTD. 		58
ATK CHEMICAL COMPANY LIMITED 		60
Zhejiang J&C Biological Technology Co.,Limited 		58
Aladdin Scientific 		58
Hubei Zhongshan Medical Technology Co., Ltd 58
Jinan Chuanbei Biotechnology Co., Ltd 58
Houxu Chemical (Shandong) Co., Ltd 58
Jinan shenlikang chemical technology co. LTD 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Shanghai Lollane Biological Technology Co.,Ltd. 55

View Lastest Price from 2-Propen-1-one, 1-[4-[8-[[3-methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]phenyl]amino]pyrimido[5,4-d]pyrimidin-2-yl]-1-piperazinyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BI-4142 pictures 2024-09-18 BI-4142
2682003-36-5
 US $0.00-0.00 / MG 10MG 99% HPLC 10000 HangZhou RunYan Pharma Technology Co.,LTD.
  • BI-4142 pictures
  • BI-4142
    2682003-36-5
  • US $0.00-0.00 / MG
  • 99% HPLC
  • HangZhou RunYan Pharma Technology Co.,LTD.
2-Propen-1-one, 1-[4-[8-[[3-methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]phenyl]amino]pyrimido[5,4-d]pyrimidin-2-yl]-1-piperazinyl]- BI-4142 1-{4-[8-({3-methyl-4-[(1-methyl-1H-1,3-benzodiazol-5-yl)oxy]phenyl}amino)pyrimido[5,4-d][1,3]diazin-2-yl]piperazin-1-yl}prop-2-en-1-one 2682003-36-5 C28H27N9O2