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ChemicalBook >> CAS DataBase List >>Glycine, N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[4-[[[3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl]carbonyl]amino]-2-methoxyphenyl]-, (acetyloxy)methyl ester

Glycine, N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[4-[[[3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl]carbonyl]amino]-2-methoxyphenyl]-, (acetyloxy)methyl ester

Glycine, N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[4-[[[3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl]carbonyl]amino]-2-methoxyphenyl]-, (acetyloxy)methyl ester Structure
Glycine, N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[4-[[[3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl]carbonyl]amino]-2-methoxyphenyl]-, (acetyloxy)methyl ester structure
CAS No.
1802991-71-4
Chemical Name:
Glycine, N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[4-[[[3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl]carbonyl]amino]-2-methoxyphenyl]-, (acetyloxy)methyl ester
Synonyms
Thallos AM;Glycine, N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[4-[[[3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl]carbonyl]amino]-2-methoxyphenyl]-, (acetyloxy)methyl ester
CBNumber:
CB312280408
Molecular Formula:
C42H36N2O17
Molecular Weight:
840.74
MDL Number:
MOL File:
1802991-71-4.mol
Last updated:2023-07-12 16:59:46
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Glycine, N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[4-[[[3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl]carbonyl]amino]-2-methoxyphenyl]-, (acetyloxy)methyl ester Properties

Boiling point 901.3±65.0 °C(Predicted)
Density 1.50±0.1 g/cm3(Predicted)
storage temp. -20°C
form A solid
pka 12.19±0.70(Predicted)

Glycine, N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[4-[[[3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl]carbonyl]amino]-2-methoxyphenyl]-, (acetyloxy)methyl ester Chemical Properties,Uses,Production

Biological Activity

Thallos AM is a cell-permeable fluorescent thallium indicator that has been used to measure the activity of sodium or potassium channels.1,2 It can also be used for transporters and G protein-coupled receptors (GPCRs). It displays excitation/emission maxima of 490/515 nm, respectively.

References

1.Du, Y., Days, E., Romaine, I., et al.Development and validation of a thallium flux-based functional assay for the sodium channel NaV1.7 and its utility for lead discovery and compound profilingACS Chem. Neurosci.6(6)871-878(2015) 2.Dutter, B.F., Ender, A., Sulikowski, G.A., et al.Rhodol-based thallium sensors for cellular imaging of potassium channel activityOrg. Biomol. Chem.16(31)5575-5579(2018)

Glycine, N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[4-[[[3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl]carbonyl]amino]-2-methoxyphenyl]-, (acetyloxy)methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Glycine, N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[4-[[[3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl]carbonyl]amino]-2-methoxyphenyl]-, (acetyloxy)methyl ester Suppliers

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Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
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Shanghai Yifei Biotechnology Co. , Ltd. 58
Glycine, N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[4-[[[3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl]carbonyl]amino]-2-methoxyphenyl]-, (acetyloxy)methyl ester Thallos AM 1802991-71-4 C42H36N2O17