IODIPAMIDE
- CAS No.
- 606-17-7
- Chemical Name:
- IODIPAMIDE
- Synonyms
- bilignost;adipiodon;biligrafin;transbilix;ADIPIODONE;cholospect;IODIPAMIDE;cholografin;iodipamicacid;Iodipamide (200 mg)
- CBNumber:
- CB3125304
- Molecular Formula:
- C20H14I6N2O6
- Molecular Weight:
- 1139.76
- MDL Number:
- MFCD00058983
- MOL File:
- 606-17-7.mol
- MSDS File:
- SDS
Melting point | 306-308°C (dec.) |
---|---|
Boiling point | 908.6±65.0 °C(Predicted) |
Density | 2.5848 (estimate) |
refractive index | nD21.5 1.3294 (c = 0.445 in methanol) |
storage temp. | Room Temperature |
solubility | DMSO (Slightly), Methanol (Very Slightly) |
form | Solid |
pka | pKa 3.5(H2O) (Uncertain) |
color | White |
Water Solubility | 0.46g/L(20 ºC) |
Merck | 5022 |
FDA UNII | TKQ858A3VW |
ATC code | V08AC04 |
EPA Substance Registry System | Benzoic acid, 3,3'-[(1,6-dioxo-1,6-hexanediyl)diimino]bis[2,4,6-triiodo- (606-17-7) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H319-H315 |
Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
WGK Germany | 3 |
RTECS | DG0949500 |
HS Code | 2924296000 |
Toxicity | LD50 in mice, rats (mg/kg): 2380 ±290, 4430 ±310 i.v. (Rosenberg) |
IODIPAMIDE price More Price(13)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 1343007 | Iodipamide United States Pharmacopeia (USP) Reference Standard | 606-17-7 | 200mg | $358 | 2024-03-01 | Buy |
Sigma-Aldrich | PHR3188 | Iodipamide pharmaceutical secondary standard, certified reference material | 606-17-7 | 500MG | $162 | 2022-05-15 | Buy |
Sigma-Aldrich | I0639 | Iodipamide analytical standard, for drug analysis | 606-17-7 | 5g | $72.9 | 2022-05-15 | Buy |
TRC | I666800 | Iodipamide | 606-17-7 | 5mg | $90 | 2021-12-16 | Buy |
Biosynth Carbosynth | FI24595 | Iodipamide | 606-17-7 | 25mg | $130 | 2021-12-16 | Buy |
IODIPAMIDE Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Originator
Cholografin,Squibb,US,1954
Uses
antihypertensive, diuretic, activates K channels and AMPA receptors
Uses
Diagnostic aid (radiopaque medium-cholecystographic).
Definition
ChEBI: Adipiodone is an organoiodine compound that is 3-amino-2,4,6-triiodobenzoic acid in which one of the amino hydrogens is substituted by a 6-(3-carboxy-2,4,6-triiodoanilino)-6-oxohexanoyl group. It is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography. It has a role as a radioopaque medium. It is an organoiodine compound, a member of benzoic acids and a secondary carboxamide. It is a conjugate acid of an adipiodone(2-).
Manufacturing Process
125 g of 2,4,6-triiodo-3-amino benzoic acid are dissolved in 250 cc of chlorobenzene and 15 g of adipic acid dichloride are added at a temperature between 110° and 130°C drop by drop to the solution. After evolution of hydrochloric acid (about 2 to 3 hours) has ceased, the precipitated crude adipic acid di-(3-carboxy-2,4,6-triiodo anilide) of the above formula is filtered hot with suction, washed with chlorobenzene, extracted by boiling with methanol and, for purification, dissolved in an amount of methanolic caustic soda solution required for neutralization, filtered with charcoal, and precipitated with dilute hydrochloric acid. Yield: 82.3 g, MP 306° to 308°C (with decomposition).
brand name
Pharmaceutic necessity for Iodipamide Meglumine [Injection]. Cholografin (Bristol-Myers Squibb).
Therapeutic Function
Diagnostic aid (radiopaque medium)
Hazard
Toxic by ingestion.
IODIPAMIDE Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29825 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 8930 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20296 | 58 |
R&D Scientific Inc. | +12266000236 | sales@rdscientific.com | Canada | 1422 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3576 | 66 |
View Lastest Price from IODIPAMIDE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2020-01-10 | 3,3-Adipoyldiiminobis(2,4,6-Triiodobenzoic Acid)
606-17-7
|
US $9.80 / KG | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
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- 3,3-Adipoyldiiminobis(2,4,6-Triiodobenzoic Acid)
606-17-7
- US $9.80 / KG
- ≥98%
- Career Henan Chemical Co