HEXAMETHONIUM CHLORIDE
- CAS No.
- 60-25-3
- Chemical Name:
- HEXAMETHONIUM CHLORIDE
- Synonyms
- depressin;hexonchloride;hiohexchloride;hexonechloride;esomidchloride;methiumchloride;chloor-hexaviet;bistriumchloride;hestriumchloride;hexametonchloride
- CBNumber:
- CB3125713
- Molecular Formula:
- C12H30Cl2N2
- Molecular Weight:
- 273.29
- MDL Number:
- MFCD00031563
- MOL File:
- 60-25-3.mol
- MSDS File:
- SDS
Melting point | 292°C(dec.)(lit.) |
---|---|
Boiling point | 423.36°C (rough estimate) |
Density | 1.0558 (rough estimate) |
refractive index | 1.6400 (estimate) |
solubility | H2O: soluble |
form | solid (hygroscopic) |
color | white |
Water Solubility | almost transparency |
BRN | 3714806 |
CAS DataBase Reference | 60-25-3 |
FDA UNII | TIV4Q933FU |
EPA Substance Registry System | 1,6-Hexanediaminium, N,N,N,N',N',N'-hexamethyl-, dichloride (60-25-3) |
HEXAMETHONIUM CHLORIDE price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | H2138 | Hexamethonium chloride solid (hygroscopic) | 60-25-3 | 5g | $33.9 | 2024-03-01 | Buy |
Sigma-Aldrich | H2138 | Hexamethonium chloride solid (hygroscopic) | 60-25-3 | 25g | $84 | 2024-03-01 | Buy |
TCI Chemical | H0090 | Hexamethonium Chloride Dihydrate >99.0%(T) | 60-25-3 | 25g | $99 | 2023-01-07 | Buy |
TCI Chemical | H0090 | Hexamethonium Chloride Dihydrate >99.0%(T) | 60-25-3 | 100g | $249 | 2023-01-07 | Buy |
TCI Chemical | H0090 | Hexamethonium Chloride Dihydrate >99.0%(T) | 60-25-3 | 500g | $754 | 2023-01-07 | Buy |
HEXAMETHONIUM CHLORIDE Chemical Properties,Uses,Production
Chemical Properties
White, crystalline, hygroscopic powder; faint odor. Very soluble in water; soluble in alcohol, methanol, and n-propanol; insoluble in chloroform and ether. Available commercially as unhydrated form or as dihydrate.
Uses
Hexamethonium chloride has been used to block the responses of nicotinic receptors towards it agonists. It has also been used to study the mechanosensitivity of viscerofugal neurons.
Uses
Medicine (antihypertensive).
Uses
Hexamethonium Chloride is a ganglionic nicotinic receptor blocker.
General Description
Nicotinic acetylcholine receptor (nAChR) forms a ligand-gated ion channel made up of four different subunits. Each subunit contains an extracellular amino-terminal domain (hydrophilic) and carboxylic terminal domain and four transmembrane domains. nAChR is an allosteric and transmembrane protein localized to the neuromuscular junction.
Biochem/physiol Actions
Hexamethonium chloride preferentially blocks nicotinic receptors at autonomic ganglia, crosses blood-brain barrier only at high doses. Nicotinic acetylcholine receptor (nAChR) is responsible for cognitive functions. Blocking this receptor results in cognitive impairment. nAChR antagonist is used to study the effect of loss of receptor function. Hexamethonium has a peripheral action over blocking the nAChR.
HEXAMETHONIUM CHLORIDE Preparation Products And Raw materials
HEXAMETHONIUM CHLORIDE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
Chemsigma International Co., Ltd. | +86-18136843612 +86-19951791336 | info@chemsigma.com | China | 1342 | 58 |
Alfa Chemistry | info@alfa-chemistry.com | United States | 2344 | 58 | |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5986 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52861 | 58 |
CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20356 | 58 |
weifang runzhong fine chemical co., ltd | 536-7868377 +8618653686003 | sq@runzhongchem.com | China | 187 | 58 |
Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-17333973358 | sales06@hbduling.cn | China | 8054 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50003 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
View Lastest Price from HEXAMETHONIUM CHLORIDE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-10-14 | Hexamethonium chloride
60-25-3
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2022-10-11 | HEXAMETHONIUM CHLORIDE
60-25-3
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
- Hexamethonium chloride
60-25-3
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
- HEXAMETHONIUM CHLORIDE
60-25-3
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.