JACOZINE
- CAS No.
- 5532-23-0
- Chemical Name:
- JACOZINE
- Synonyms
- JACOZINE;Spiro[[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-3(2H),2'-oxirane]-2,7(4H)-dione, 5,6,9,11,13,14,14a,14b-octahydro-6-hydroxy-3',6-dimethyl-5-methylene-, (2'S,3'S,6R,14aR,14bR)-
- CBNumber:
- CB31414098
- Molecular Formula:
- C18H23NO6
- Molecular Weight:
- 349.38
- MDL Number:
- MOL File:
- 5532-23-0.mol
| Melting point | 228°C |
|---|---|
| FDA UNII | 73KAJ7W3HA |
JACOZINE Chemical Properties,Uses,Production
Description
A Senecio alkaloid also present in S. Jacobea, this base has [α] D - 140° (CHC13) and is hydrolyzed to retronecine and jacozinecic acid. The base contains a methylene group and the ultraviolet spectrum has a single absorption maximum at 233 mμ.
Definition
ChEBI: Jacozine is a pyrrolizine alkaloid that is seneciphylline in which the exocyclic double bond has been converted to the corresponding epoxide. It has a role as a Jacobaea metabolite. It is a macrocyclic lactone, an organic heterotricyclic compound, a pyrrolizine alkaloid, a spiro-epoxide, a tertiary alcohol and a tertiary amino compound. It is functionally related to a seneciphylline.
References
Bradbury, Culvenor., Chern. & Ind., 1021 (1954)
Bradbury, Culvenor.,Austrai. J. Chern., 7,378 (1954)
Bradbury, Willis., ibid, 9,258 (1956)
Culvenor., ibid, 17,233 (1964)
JACOZINE Preparation Products And Raw materials
JACOZINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 8670 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 |
| Supplier | Advantage |
|---|---|
| Shaanxi Didu New Materials Co. Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |