E COLI ENDONUCLEASE III
- CAS No.
- Chemical Name:
- E COLI ENDONUCLEASE III
- Synonyms
- ENDO III;NTH PROTEIN;ENDONUCLEASE III;E COLI NTH PROTEIN;E COLI ENDONUCLEASE III;THYMINE GLYCOL-DNA GLYCOSYLASE;Endonuclease III from Escherichia coli
- CBNumber:
- CB3150782
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD02265700
- MOL File:
- Mol file
Last updated:2023-04-23 13:52:06
E COLI ENDONUCLEASE III Chemical Properties,Uses,Production
Biochem/physiol Actions
Endo III, product of the nth gene, is an iron-sulfur containing DNA repair enzyme. It possesses DNA glycosylase activity with broad substrate specificity for mutated pyrimidine derivatives especially thymine glycol (Tg) but also for 5-hydroxycytosine and 5,6-dihydrothymine. In addition, it has an apurinic/apyrimidinic (AP) lyase activity which cleaves the DNA backbone by β elimination. Endo III protects E. coli cells from radiation damage caused by x-ray and UV irradiation and its activity overlaps the activity of endonuclease VIII. When overexpressed, it can also protect E.coli cells from alkylation defects caused by methylmethanesulphonate.
E COLI ENDONUCLEASE III Preparation Products And Raw materials
Raw materials
Preparation Products
E COLI ENDONUCLEASE III Suppliers
Global( 5)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
---|---|
Sigma-Aldrich | 80 |
NTH PROTEIN
THYMINE GLYCOL-DNA GLYCOSYLASE
E COLI NTH PROTEIN
E COLI ENDONUCLEASE III
ENDO III
ENDONUCLEASE III
Endonuclease III from Escherichia coli
Enzymes, Inhibitors, and Substrates
Biochemicals and Reagents
Application Index
BioChemical
Cell Stress and Refolding
Cell Signaling Enzymes