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CARYOPHYLLENE OXIDE

CARYOPHYLLENE OXIDE Structure
CARYOPHYLLENE OXIDE structure
CAS No.
1139-30-6
Chemical Name:
CARYOPHYLLENE OXIDE
Synonyms
(-)-CARYOPHYLLENE OXIDE;(-)-EPOXYCARYOPHYLLENE;Caryophylene oxide;Caryophyllene epoxide;Caryophyllene oxyde;(-)-beta-Caryophyllene epoxide;caryophyleneoxide;CARYOPHYLLENEPOXID;5-oxatricyclo(8.20.0(4,6))dodecane,4,12,12-trimethyl-9-methylene-,(1r,4r,6r,1;0s)-
CBNumber:
CB3199893
Molecular Formula:
C15H24O
Molecular Weight:
220.35
MDL Number:
MFCD00134216
MOL File:
1139-30-6.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02
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CARYOPHYLLENE OXIDE Properties

Melting point 62-63 °C(lit.)
Boiling point 301.3°C (rough estimate)
Density 0.96
refractive index 1.4956
FEMA 4085 | BETA-CARYOPHYLLENE OXIDE
Flash point >230 °F
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Crystalline Powder
color White
Odor at 100.00 %. sweet fresh dry woody spicy
Odor Type woody
optical activity [α]20/D 71±1°, c = 2% in chloroform
biological source synthetic
Water Solubility insoluble in water
JECFA Number 1575
BRN 148213
LogP 4.57
Substances Added to Food (formerly EAFUS) BETA-CARYOPHYLLENE OXIDE
EWG's Food Scores 1
FDA UNII S2XU9K448U
EPA Substance Registry System 5-Oxatricyclo[8.2.0.04,6]dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)- (1139-30-6)
UNSPSC Code 85151701
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09
Signal word  Warning
Hazard statements  H315-H319-H411
Precautionary statements  P273-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/38
Safety Statements  26
WGK Germany  2
RTECS  RP5530000
F  1-10
HS Code  29109000
Hazardous Substances Data 1139-30-6(Hazardous Substances Data)
NFPA 704
0
2 0

CARYOPHYLLENE OXIDE price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 91034 (?)-Caryophyllene oxide analytical standard 1139-30-6 100mg $100 2024-03-01 Buy
Sigma-Aldrich 22076 (?)-Caryophyllene oxide ≥99.0% (sum of enantiomers, GC) 1139-30-6 1g $104 2024-03-01 Buy
Sigma-Aldrich W408588 (−)-Caryophyllene oxide natural (US), ≥95%, FG 1139-30-6 SAMPLE-K $56.2 2023-06-20 Buy
Sigma-Aldrich W408588 (−)-Caryophyllene oxide natural (US), ≥95%, FG 1139-30-6 100G $292 2023-06-20 Buy
Sigma-Aldrich W408588 (−)-Caryophyllene oxide natural (US), ≥95%, FG 1139-30-6 1KG $1010 2023-06-20 Buy
Product number Packaging Price Buy
91034 100mg $100 Buy
22076 1g $104 Buy
W408588 SAMPLE-K $56.2 Buy
W408588 100G $292 Buy
W408588 1KG $1010 Buy

CARYOPHYLLENE OXIDE Chemical Properties,Uses,Production

Chemical Properties

Colorless solid; sweet fruity aroma.

Chemical Properties

white crystalline powder

Chemical Properties

Caryophyllene oxide which has a woody, slightly ambergris-like odor, can be prepared by treatment of ??-caryophyllene with organic peracids.

Occurrence

Reported found in Nepeta betonicifolia C.A. Meyer oil Turkey (39.20%), geranium rose-scented oil (Pelargonium spp.) Cuba (14.70%), melissa oil (9.99%), guava leaf oil Cuba (8.20%), etc.

Uses

β-Caryophyllene Epoxide, and its derivatives has shown to have microbial transformation and butyrylcholinesterase inhibitory activity. It is also the main active constituent of essential oils obtained from various plants, used for flavoring and fragrances.

Definition

ChEBI: A natural product found in Cupania cinerea.

Aroma threshold values

Medium strength odor, woody type.

Biological Activity

β-caryophyllene oxide is a potent anti-cancer agent which also exerts antioxidant, anti-inflammatory, and antiviral properties. It is a strong inhibitor of drug-metabolizing enzyme cytochromes P4503A (CYP3A) activities both in r at and human hepatic microsomes. BCPO also exerts analgesic, antifungal, antibacterial, and genoprotective activities.

Safety Profile

Low toxicity by ingestion and skin contact. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

Purify the oxide by TLC on silica gel with EtOAc/pet ether (b 60-80o) (15:85), and recrystallise it from MeOH or *C6H6. [NMR: Warnhoff Can J Chem 42 1664 1964, Ramage & Whitehead J Chem Soc 4336 1954, Beilstein 17 IV 392.]

CARYOPHYLLENE OXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

CARYOPHYLLENE OXIDE Suppliers

Global( 165)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Weibang Biotechnology Co., Ltd 		+8615531157085 abby@weibangbio.com China 8804 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81148696 +86-15536356810 1022@dideu.com China 3882 58
Hebei Mujin Biotechnology Co.,Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12827 58
Shandong Deshang Chemical Co., Ltd. 		+86-0531-8875-2665 +8613153039501 info@deshangchem.com China 662 58
Hebei Zhuanglai Chemical Trading Co Ltd 		+86-16264648883 +86-16264648883 niki@zlchemi.com China 3712 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21632 55
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29871 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Supplier Advantage
Hebei Weibang Biotechnology Co., Ltd 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Hebei Mujin Biotechnology Co.,Ltd 		58
Shandong Deshang Chemical Co., Ltd. 		58
Hebei Zhuanglai Chemical Trading Co Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Zheyan Biotech Co., Ltd. 		58
career henan chemical co 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Chongqing Chemdad Co., Ltd 		58

View Lastest Price from CARYOPHYLLENE OXIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CARYOPHYLLENE OXIDE pictures 2025-02-18 CARYOPHYLLENE OXIDE
1139-30-6
 US $0.00 / KG 1KG 99% 100 MT Hebei Weibang Biotechnology Co., Ltd
CARYOPHYLLENE OXIDE pictures 2025-02-18 CARYOPHYLLENE OXIDE
1139-30-6
 US $0.00 / kg 1kg 99% 1000tons Hebei Mujin Biotechnology Co.,Ltd
Caryophyllene Oxide pictures 2025-02-18 Caryophyllene Oxide
1139-30-6
 US $150.00 / kg 1kg 99% 500kg Hebei Zhuanglai Chemical Trading Co Ltd

CARYOPHYLLENE OXIDE Spectrum

CARYOPHYLLENE OXIDE(1139-30-6)MSCARYOPHYLLENE OXIDE(1139-30-6)1HNMRCARYOPHYLLENE OXIDE(1139-30-6)13CNMRCARYOPHYLLENE OXIDE(1139-30-6)IR1CARYOPHYLLENE OXIDE(1139-30-6)IR2

1139-30-6(CARYOPHYLLENE OXIDE)Related Search:

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(-)-5-Oxatricyclo[8.2.0.0(4,6)]dodecane,4,12,12-trimethyl-9-methylene-, [1R-(1R*,4R*,6R*,10S*)]- caryophylleneepoxide (1R,4R,6R,10S)-9-METHYLENE-4,12,12-TRIMETHYL-5-OXATRICYCLO[8.2.0.0(4,6)]DODECANE CARYOPHYLLENE OXIDE caryophylleneoxide,(1R,4R,6R,10S)-4,12,12-trimethyl-9-methylene-5-oxatricyclo[8.2.0.0]4,6)]dodecane 5-Oxatricyclo8.2.0.04,6dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)- (1R-(1R*,4R*,6R*,10S*))-4,12,12-Trimethyl-9-methylen-5-oxatricyclo(8.2.0.04,6)dodecan (-)-Epoxycaryophyllene, (1R,4R,6R,10S)-9-Methylene-4,12,12-trimethyl-5-oxatricyclo[8.2.0.04,6]dodecane (1R,4R,6R,10S)-4,12,12-Trimethyl-9-methylene-5-oxatricyclo[8.2.0.04,6]dodecane (1R,5S,8R,11R)-4-Methylene-7,7,11-trimethyl-12-oxatricyclo[9.1.0.05,8]dodecane (1β,4R,5R,9α)-4,11,11-Trimethyl-8-methylene-4,5-epoxybicyclo[7.2.0]undecane (-)-Caryophyllene oxide,97% (-)-CARYOPHYLLENE OXIDE 95% CARYOPHYLLENE OXIDE TECH. 90% CARYOPHYLLENE OXIDE 95+% (-)-beta-caryophylleneepoxid (-)-beta-caryophylleneepoxide (-)-Epoxydihydrocaryophyllene (1r-(1r*,4r*,6r*,10s*))-4,12,12-trimethyl-9-methylene-5-oxatricyclo(8.2.0.04,6)dodecane (1r-(1r,4r,6r,10s))-4,12,12-trimethyl (1r-(1r,4r,6r,10s))-4,12,12-trimethyl-9-methylene-5-oxatricyclo(8.2.0.04,6)dodecane ,6r,10s)- 0s)- 4,11,11-Trimethyl-8-methylene-5-oxatricyclo(8.2.0.0(4,6))dodecane 4,12,12-trimethyl-9-methylene-5-oxatricyclo[8.2.0.]dodecane (caryophyllene oxide) 4theta,6theta,10s)]-thet 5-)xatricyclo[8.2.0.0(4,6))dodecane, 6,,11,11-trimethyl-2-methylene, [1R-(1R*,4R*,6R*,10S*)]- 5-oxatricyclo(8.2.0.0(4,6))dodecane,4,12,12-trimethyl-9-methylene-,(1r-(1r*,4 5-oxatricyclo(8.2.0.0(sup4,6))dodecane,4,12,12-trimethyl-9-methylene-,(1r,4r 5-Oxatricyclo(8.2.0.04,6)dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)- 5-Oxatricyclo[8.2.0.0(4,6)-]dodecane, 4,12,12-trimethyl-9-methylene-, [1R-(1R*,4R*,6R*,10S*)]- 5-oxatricyclo[8.2.0.04,6]dodecane,,12,12-trimethyl-3-methylene-[1r- 6]dodecane,4,12,12-trimethyl-9-methylene-,[1R-(1R*,4R*,6R*,10S*)]-5-Oxatricyclo[8.2.0.04 6]dodecane,4,12,12-trimethyl-9-methylene-5-oxatricyclo[8.2.0.0[1theta-(1 6r*,10s*))-r beta-Caryophyllene oxide beta-caryophylleneepoxide beta-caryophylleneoxide (-)-Caryophyllene oxide, 95% 10GR CARYLOPHYLLENE OXIDE (-)-CARYOPHYLLENE OXIDE, >= 99.0 % G (-)-Caryophyllene oxide@100 μg/mL in Methanol (-)-Caryophyllene oxide, 95% Caryopyllene oxide Caryophyllene oxide USP/EP/BP β-Caryophyllene Epoxide TIANFUCHEM--1139-30-6--High purity CARYOPHYLLENE OXIDE in stock (-)-Caryophyllene oxide, 95%, DXP 5648 DXP5648 DXP-5648 (-)-beta-Caryophyllene epoxide caryophyleneoxide Caryophyllene epoxide Caryophyllene oxyde (-)-EPOXYCARYOPHYLLENE (-)-CARYOPHYLLENE OXIDE CARYOPHYLLENEPOXID