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4-THIOURIDINE

4-THIOURIDINE Structure
4-THIOURIDINE structure
CAS No.
13957-31-8
Chemical Name:
4-THIOURIDINE
Synonyms
4-SH-Ur;NSC 518132;thiouridine;4-THIOURIDINE;THIOURIDINE, 4-;Uridine, 4-thio-;1-((2R,3R,4S,5R);4-Thio-D-uridine;4-thiouridineapprox.;4-THIOURIDINE USP/EP/BP
CBNumber:
CB3202841
Molecular Formula:
C9H12N2O5S
Molecular Weight:
260.27
MDL Number:
MFCD00006538
MOL File:
13957-31-8.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02
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4-THIOURIDINE Properties

Melting point 139-140℃ (ethanol )
Density 1.72±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
form crystalline
pka 4.75±0.20(Predicted)
color light yellow
PH 8.2
biological source synthetic (organic)
Water Solubility Soluble in water (20 mg/ml), and methanol (10 mg/ml).
λmax 245，331 (pH 6.5)；316 (pH 12)
InChIKey ZLOIGESWDJYCTF-XVFCMESISA-N
CAS DataBase Reference 13957-31-8(CAS DataBase Reference)
FDA UNII U9TYQ2R33J
UNSPSC Code 41106305
NACRES NA.51

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Safety Statements  24/25
WGK Germany  3
HS Code  29349990

4-THIOURIDINE price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T4509 4-Thiouridine ≥98% 13957-31-8 25mg $225 2024-03-01 Buy
Sigma-Aldrich T4509 4-Thiouridine ≥98% 13957-31-8 100mg $592 2024-03-01 Buy
Alfa Aesar J60679 4-Thiouridine, 98+% 13957-31-8 100mg $499 2024-03-01 Buy
Alfa Aesar J60679 4-Thiouridine 98+% 13957-31-8 250mg $749 2024-03-01 Buy
Cayman Chemical 16373 4-Thiouridine ≥98% 13957-31-8 5mg $37 2024-03-01 Buy
Product number Packaging Price Buy
T4509 25mg $225 Buy
T4509 100mg $592 Buy
J60679 100mg $499 Buy
J60679 250mg $749 Buy
16373 5mg $37 Buy

4-THIOURIDINE Chemical Properties,Uses,Production

Description

4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU differs from uridine only by a single sulfur substitution. This offers the advantage of incorporating into an RNA chain with minimal structural perturbation and with similar base-pairing properties, reducing the likelihood that substitution will impair RNA interactions or activities.

Uses

Nucleotide analogue, essential for cell growth in certain bacterial species. This compound is also able to chelate with certain metal ions, and in tRNA it can act as a built-in antiphotomutagenic agent that protects Escherichia coli cells against mutagenesis.

Uses

4-Thiouridine is a constituent of several transfer RNA's. 4-Thiouridine is a thionucleobase used as an antisense agent. Widely used for RNA analysis including RNA-RNA cross coupling and RNA labelling. 4-Thiouridine is a photoreactive (crosslinking) uridine analogue that upon phosphorylation to 4-thioUTP may be incorporated into RNA structures. 4-Thiouridine may be used to study the specificity and kinetics of uridine-cytidine kinases. 4-Thio Uridine is typically used to modify oligos slated for RNA, or RNA-protein, structural studies. A 4-thio-rU modified RNA pentamer was used to study the effect of this modification on codon-anticodon interaction when it is in the wobble position of tRNA.

Definition

ChEBI: A thiouridine in which the oxygen replaced by sulfur is that at C-4.

General Description

4-Thiouridine is a photoreactive uridine analog.

Biochem/physiol Actions

4-Thiouridine plays a role in assessing nascent RNA synthesis. It also enhances site-specific crosslinking. 4-Thiouridine also acts as a photoaffinity probe due to its stability even while lacking specific photoactivation. It can also be incorporated into RNAs.

storage

Store at -20°C

4-THIOURIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

4-THIOURIDINE Suppliers

Global( 155)Suppliers
Supplier Tel Email Country ProdList Advantage
NewCan Biotech Limited 		+86-0571-86912261 +8613735419629 sales@newcanbio.com China 9983 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29871 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10311 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
Nanjing Baifuli Technology Co., Ltd. 		+86-15335185688 sales@unisyn.cn CHINA 332 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Supplier Advantage
NewCan Biotech Limited 		58
career henan chemical co 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
Nanjing Baifuli Technology Co., Ltd. 		58
Hubei xin bonus chemical co. LTD 		58
BOC Sciences 		58
Chongqing Chemdad Co., Ltd 		58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		58
TargetMol Chemicals Inc. 		58

View Lastest Price from 4-THIOURIDINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Thiouridine;4-SH-Ur pictures 2025-01-03 4-Thiouridine;4-SH-Ur
13957-31-8
 US $0.00-0.00 / g 1g 97% 100g NewCan Biotech Limited
4-Thiouridine pictures 2024-11-19 4-Thiouridine
13957-31-8
 US $40.00-129.00 / mg 99.89% 10g TargetMol Chemicals Inc.
4-Thiouridine pictures 2022-01-27 4-Thiouridine
13957-31-8
 US $0.00 / KG 1KG 97.6% 100 tons Honest Joy Holdings Limited
  • 4-Thiouridine pictures
  • 4-Thiouridine
    13957-31-8
  • US $40.00-129.00 / mg
  • 99.89%
  • TargetMol Chemicals Inc.
  • 4-Thiouridine pictures
  • 4-Thiouridine
    13957-31-8
  • US $0.00 / KG
  • 97.6%
  • Honest Joy Holdings Limited

4-THIOURIDINE Spectrum

4-THIOURIDINE(13957-31-8)1HNMR4-THIOURIDINE(13957-31-8)FT-IR

13957-31-8(4-THIOURIDINE)Related Search:

4-THIOURIDINE 2-THIOURIDINE 5-METHYL-2-THIOURIDINE 5-methylaminomethyl-2-thiouridine 5-FLUORO-2'-O-METHYL-4-THIOURIDINE
4-THIO-UMP DISODIUM SALT 5-BROMO-2'-DEOXY-4-THIOURIDINE,5-BROMO-2''-DEOXY-4-THIOURIDINE 98.0% 4-thiouridine triphosphate 2'-deoxy-4'-thiouridine 5-(2-bromovinyl)-2'-deoxy-4'-thiouridine
5-(carboxymethylaminomethyl)-2-thiouridine 2'-O-methyl-2-thiouridine 6-aza-2-thiouridine THIOURIDINE, 4-(RG) 4-THIOURIDINE-5'-TRIPHOSPHATE LITHIUM SALT
4-THIOURIDINE [2-14C] 2',3'-Didehydro-2',3'-dideoxy-4-thiouridine 5-[(E)-2-Bromoethenyl]-2'-deoxy-4'-thiouridine

1of4

1-((2R,3R,4S,5R) -4-thioxo-3,4-dihydropyrimidin-2(1H) THIOURIDINE, 4- 4-THIOURIDINE thiouridine 4-thiouridineapprox. 4-Thio-D-uridine 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-4-thioxo-3,4-dihydropyriMidin-2(1H)-one 4-SH-Ur NSC 518132 Uridine, 4-thio- 4-THIOURIDINE USP/EP/BP 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidenepyrimidin-2-one 4-thiouridine,RNA-modified nucleoside s4U 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-thioxo-pyrimidin-2-one 4-Thiouridine, RNA synthesis inhibitor 4-Thiouridine, 10 mM in DMSO 13957-31-8 Biochemicals and Reagents BioChemical Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs Biochemicals and Reagents Nucleoside Analogs Nucleosides, Nucleotides, Oligonucleotides Bases & Related Reagents Nucleotides Sulfur & Selenium Compounds