enniatin A1
- CAS No.
- 4530-21-6
- Chemical Name:
- enniatin A1
- Synonyms
- enniatin A1;2-(N-Methyl-L-valine)enniatin A;(3S,6R,9S,12R,15S,18R)-3,9-bis[(2S)-butan-2-yl]-4,10,16-trimethyl-6,12,15,18-tetra(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone;Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl]
- CBNumber:
- CB32079106
- Molecular Formula:
- C35H61N3O9
- Molecular Weight:
- 667.879
- MDL Number:
- MFCD14635385
- MOL File:
- 4530-21-6.mol
- MSDS File:
- SDS
| Melting point | 116-117 °C |
|---|---|
| Boiling point | 840.5±65.0 °C(Predicted) |
| Density | 1.027±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: soluble10mg/mL |
| form | White to off-white crystalline solid. |
| pka | -1.44±0.70(Predicted) |
| FDA UNII | 39458RI529 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301+H311+H331 |
| Precautionary statements | P280-P301+P310+P330-P302+P352+P312-P304+P340+P311 |
| Hazard Codes | T |
| Risk Statements | 23/24/25 |
| Safety Statements | 45 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| HazardClass | 6.1(a) |
| PackingGroup | I |
enniatin A1 price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | E5161 | Enniatin A1 from Gnomonia errabunda, ≥95% (HPLC) | 4530-21-6 | 1mg | $211 | 2024-03-01 | Buy |
| Cayman Chemical | 17457 | Enniatin A1 ≥99% | 4530-21-6 | 1mg | $166 | 2024-03-01 | Buy |
| Cayman Chemical | 17457 | Enniatin A1 ≥99% | 4530-21-6 | 5mg | $698 | 2024-03-01 | Buy |
| TRC | E555995 | Enniatin A1 | 4530-21-6 | 10mg | $1630 | 2021-12-16 | Buy |
| TRC | E555995 | Enniatin A1 | 4530-21-6 | 1mg | $175 | 2021-12-16 | Buy |
enniatin A1 Chemical Properties,Uses,Production
Uses
Enniatin A1 is a mycotoxin capable of creating negative CNS effects due to their ability to cross the blod-brain barrier. Secondary metabolite of microbes, it is associated with mold, moisture damage and asthma development.
Uses
Enniatins are a family of depsipeptide ionophores produced by several Fusarium species. Recently, the effects of the enniatins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus. Enniatin A1 is one of four major analogues of the enniatin complex .
Uses
Enniatins are a family of depsipeptide ionophores, produced several Fusarium species. More recently, the effects of the ennitins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumour action have received more focus. Enniatin A1 is one of four major analogues of the enniatin complex and has previously not been available for investigation.
Definition
ChEBI: An enniatin obtained from formal cyclocondensation of one N-[(2R)-2-hydroxy-3-methylbutanoyl]-N-methyl-L-valine and two N-[(2R)-2-hydroxy-3-methylbu anoyl]-N-methyl-L-isoleucine units.
Biochem/physiol Actions
Enniatins are a group of cyclohexadepsipeptide mycotoxins produced by Gnomonia errabuda and several Fusaria species, with phytotoxic, antibiotic, and insecticidal activities. Enniatins function as ionophors by their incorporation into the cellular membrane to form dimeric structures that transport monovalent ions across the membrane (especially the mitochondrial membranes) affecting oxidative phosphorylation uncoupling. It has been demonstrated that enniatins have a cytotoxic effect on human cancer cells. Furthermore, incubation of H4IIE hepatoma cells with enniatins strongly diminished phosphorylation of the ERK (p44/p42).
enniatin A1 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 3003 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19741 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 13675144456 | sean.lv@synzest.com | China | 11438 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29774 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
View Lastest Price from enniatin A1 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-28 | Enniatin A1
4530-21-6
|
US $718.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2024-08-12 | enniatin A1
4530-21-6
|
US $25.00-11.00 / KG | 1KG | 99% | 200000KG | Shaanxi Dideu Medichem Co. Ltd |
-
- Enniatin A1
4530-21-6
- US $718.00 / mg
- TargetMol Chemicals Inc.
-
- enniatin A1
4530-21-6
- US $25.00-11.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd