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Methyl 3-amino-4-chlorobenzoate

CAS No.
40872-87-5
Chemical Name:
Methyl 3-amino-4-chlorobenzoate
Synonyms
Intedanib Impurity 5;Methyl 3-Amino-4-chlorobenzene;METHYL 3-AMINO-4-CHLOROBENZOATE;METHYL, 4-CHLORO-3-AMINOBENZOATE;Methyl3-Amino-4-chlorobenzoate>3-amino-4-chloro-2-methylbenzoate;Amino chlorobenzoic acid methyl ester;3-AMINO-4-CHLOROBENZOIC ACID METHYL ESTER;Methyl 3-AMino-4-chlorobenzoate, 98.0%(GC&T;Benzoic acid, 3-aMino-4-chloro-, Methyl ester
CBNumber:
CB3211933
Molecular Formula:
C8H8ClNO2
Molecular Weight:
185.61
MDL Number:
MFCD03470533
MOL File:
40872-87-5.mol
MSDS File:
SDS
Last updated:2023-06-08 17:06:37

Methyl 3-amino-4-chlorobenzoate Properties

Melting point 83 °C
Boiling point 292.1±20.0 °C(Predicted)
Density 1.311±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form crystalline powder
pka 1.51±0.10(Predicted)
color Pale lemon/gold
CAS DataBase Reference 40872-87-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xi
HS Code  2916399090
NFPA 704
0
1 0

Methyl 3-amino-4-chlorobenzoate price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical M1778 Methyl 3-Amino-4-chlorobenzoate >98.0%(GC)(T) 40872-87-5 5g $54 2024-03-01 Buy
TCI Chemical M1778 Methyl 3-Amino-4-chlorobenzoate >98.0%(GC)(T) 40872-87-5 25g $181 2024-03-01 Buy
TRC M328668 Methyl 3-Amino-4-chlorobenzoate 40872-87-5 500mg $65 2021-12-16 Buy
Apolloscientific OR2041 Methyl 3-Amino-4-chlorobenzoate 40872-87-5 25g $58 2021-12-16 Buy
SynQuest Laboratories 4658-5-X6 Methyl 3-amino-4-chlorobenzoate 40872-87-5 25g $64 2021-12-16 Buy
Product number Packaging Price Buy
M1778 5g $54 Buy
M1778 25g $181 Buy
M328668 500mg $65 Buy
OR2041 25g $58 Buy
4658-5-X6 25g $64 Buy

Methyl 3-amino-4-chlorobenzoate Chemical Properties,Uses,Production

Synthesis

To a solution of 3-amino-4-chlorobenzoic acid (15.0 g, 88.0 mmol) in methanol (90.0 mL), thionyl chloride (13.0 mL) was added drop-wise at 0 °C. The resulting mixture was refluxed for 12h. After completion of the reaction, the reaction mixture was concentrated under reduced pressure. The residue was diluted with water (150 mL) and extracted with ethyl acetate. The organic layer was washed with sodium bicarbonate (50 mL) and brine solution (50 mL) and dried over sodium sulfate. The organic layer was removed under a rotary evaporator to yield Methyl 3-amino-4-chlorobenzoate (15.0 g, 92.5 per cent) as an off-white solid. 1H NMR (400 MHz, CDC13) δ 3.88 (s, 3H), 4.26 (brs, 2H), 7.29 (d, J = 8.2 Hz, 1H), 7.34-7.37 (dd, J = 1.9, 8.2 Hz, 1H), 7.45 (d, J = 1.9 Hz, 1H).

Methyl 3-amino-4-chlorobenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 146)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
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View Lastest Price from Methyl 3-amino-4-chlorobenzoate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
methyl 3-amino-4-chlorobenzoate pictures 2019-07-06 methyl 3-amino-4-chlorobenzoate
40872-87-5
US $7.00 / kg 1kg 99% 100kg Career Henan Chemical Co
3-AMINO-4-CHLOROBENZOIC ACID METHYL ESTER METHYL 3-AMINO-4-CHLOROBENZOATE METHYL, 4-CHLORO-3-AMINOBENZOATE Amino chlorobenzoic acid methyl ester Methyl 3-Amino-4-chlorobenzene Benzoic acid, 3-aMino-4-chloro-, Methyl ester Methyl 3-AMino-4-chlorobenzoate, 98.0%(GC&T Intedanib Impurity 5 3-amino-4-chloro-2-methylbenzoate Methyl3-Amino-4-chlorobenzoate> Benzoic acid, 3-amino-4-chloro-, methyl ester (9CI, ACI) 3-amino-4-chloro-Benzoic acid methyl ester (9CI ACI) 40872-87-5 FINE Chemical & INTERMEDIATES Aromatic Esters