(20S)-3β,20-Bis(dimethylamino)-4α,14-dimethyl-9,19-cyclo-5α-pregn-6-en-16α-ol

CAS No.
58672-78-9
Chemical Name:
(20S)-3β,20-Bis(dimethylamino)-4α,14-dimethyl-9,19-cyclo-5α-pregn-6-en-16α-ol
Synonyms
Cyclobullatine A;(20S)-3β,20-Bis(dimethylamino)-4α,14-dimethyl-9,19-cyclo-5α-pregn-6-en-16α-ol;9,19-Cyclopregn-6-en-16-ol, 3,20-bis(dimethylamino)-4,14-dimethyl-, (3β,4α,5α,16α,20S)- (9CI)
CBNumber:
CB32308246
Molecular Formula:
C27H46N2O
Molecular Weight:
414.67
MDL Number:
MOL File:
58672-78-9.mol

(20S)-3β,20-Bis(dimethylamino)-4α,14-dimethyl-9,19-cyclo-5α-pregn-6-en-16α-ol Properties

Melting point 275°C

(20S)-3β,20-Bis(dimethylamino)-4α,14-dimethyl-9,19-cyclo-5α-pregn-6-en-16α-ol Chemical Properties,Uses,Production

Description

Buxus sempervirens var. bullatus elaborates this alkaloid which furnishes colourless needles from Me2CO. It has a specific rotation of [α]25D - 99° (c 0.40, EtOH). Catalytic hydrogenation yields the dihydro derivative with m.p. 215-7°C and specific rotation of [α]25D+ 37° (c 0.45, EtOH).

References

Bauerova, Paulik, Collect. Czech. Chem. Commun., 40, 3055 (1975)

(20S)-3β,20-Bis(dimethylamino)-4α,14-dimethyl-9,19-cyclo-5α-pregn-6-en-16α-ol Preparation Products And Raw materials

Raw materials

Preparation Products

(20S)-3β,20-Bis(dimethylamino)-4α,14-dimethyl-9,19-cyclo-5α-pregn-6-en-16α-ol Cyclobullatine A 9,19-Cyclopregn-6-en-16-ol, 3,20-bis(dimethylamino)-4,14-dimethyl-, (3β,4α,5α,16α,20S)- (9CI) 58672-78-9