ANTI-MUNC-18-1

CAS No.
Chemical Name:
ANTI-MUNC-18-1
Synonyms
Anti-UNC18;Anti-HUNC18;ANTI-STXBP1;ANTI-RB-SEC-1;ANTI-MUNC-18-1;ANTI-MUNC-18ALPHA;ANTI-SYNTAXIN-BINDING PROTEIN 1;Anti-Munc-18-1 antibody produced in rabbit;Monoclonal Anti-STXBP1 antibody produced in mouse;Anti-MUNC18/STXBP1 (Isoform A) antibody produced in goat
CBNumber:
CB3245703
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD07370408
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

ANTI-MUNC-18-1 Properties

storage temp. −20°C
form buffered aqueous solution

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P305+P351+P338
WGK Germany  3

ANTI-MUNC-18-1 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SAB2500659 Anti-MUNC18/STXBP1 (Isoform A) antibody produced in goat affinity isolated antibody, buffered aqueous solution 100μG $568 2024-03-01 Buy
Sigma-Aldrich M2694 Anti-Munc-18-1 antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution 200μL $538 2024-03-01 Buy
Product number Packaging Price Buy
SAB2500659 100μG $568 Buy
M2694 200μL $538 Buy

ANTI-MUNC-18-1 Chemical Properties,Uses,Production

Uses

Anti-Munc-18-1 antibody produced in rabbit has been used in immunoblotting and immunofluorescence.

General Description

Munc-18-1 (67 kDa) is an abundant neuronal protein that tightly binds to the synaptic fusion protein syntaxin. It is primarily expressed in neuronal tissues. Both Munc-18-1 and 2 isoforms bind tightly to syntaxins 1A, 2, and 3.

Biochem/physiol Actions

Munc-18-1 functions in synaptic vesicle exocytosis. It modulates neurotransmission by associating with syntaxin 1. Munc-18-1 binds to both syntaxin 1A and 1B isoforms, inhibiting the binding of t-soluble N-ethylmaleimide-sensitive factor-attached protein receptor (SNARE) synaptobrevin/vesicle-associated membrane protein (VAMP) and SNAP25 to syntaxin 1 and preventing SNARE assembly. Munc-18 is required for neurotransmitter secretion from synaptic vesicles throughout development and has been implicated in axonal branching in hippocampal neurons.

ANTI-MUNC-18-1 Preparation Products And Raw materials

Raw materials

Preparation Products

ANTI-RB-SEC-1 ANTI-MUNC-18-1 ANTI-MUNC-18ALPHA ANTI-SYNTAXIN-BINDING PROTEIN 1 ANTI-STXBP1 Anti-Munc-18-1 antibody produced in rabbit Anti-Munc-18α, Anti-rb-Sec-1, Anti-STXBP1, Anti-Syntaxin-binding protein 1 Monoclonal Anti-STXBP1 antibody produced in mouse Anti-HUNC18 Anti-UNC18 Anti-MUNC18/STXBP1 (Isoform A) antibody produced in goat